PAR-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPAR-2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36188
Quantity10 µM
Specieshuman
NCBI Full Gene NameF2R like trypsin receptor 1
NCBI Gene AliasesGPR11, PAR2
TypesiRNA/dsRNA
Gene Namecoagulation factor II (thrombin) receptor-like 1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) SerpinB3/Protease Activated Receptor-2 Axis Is Essential for SARS CoV-2 InfectionACS Infectious DiseasesSeptember 12, 2025Ilaria Frasson, Santina Quarta, Mariagrazia Ruvoletto, Alessandra Biasiolo, Monica Chinellato, Cristian Turato, Maristella Maggi, Laura Cendron, Sara N. Richter, Patrizia Pontissotransfections were carried out using Lipofectamine 3000 with 25 nM PAR2 siRNA (Santa Cruz Biotechnology, sc-36188, Dallas, Texas, USA) and negative control siRNA (Qiagen, Hilden, Germany). Forty-eight hours post-transfection,

(2) PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451BiomaterialsMarch 1, 2025Divya Bhansali, Nguyen H. Tu, Kenji Inoue, Shavonne Teng, Tianyu Li, Hung D. Tran, Dong H. Kim, Jessy Dong, Chloe J. Peach, Badr Sokrat, et al.5 % CO2 for 24 h prior to transfection with predesigned F2RL1 siRNA (Santa Cruz Biotechnology, Cat# sc-36188) and control siRNA (Santa Cruz Biotechnology, Cat# sc-37007, a non-targeting 20–25 nt siRNA). After

(3) Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoagingRedox biologyAugust 1, 2021Bang E, Kim DH, Chung HY.

(4) Signaling Pathways Potentially Responsible for Foam Cell Formation: Cholesterol Accumulation or Inflammatory Response-What is First?International journal of molecular sciencesApril 14, 2020Orekhov AN, Sukhorukov VN, Nikiforov NG, Kubekina MV, Sobenin IA, Foxx KK, Pintus S, Stegmaier P, Stelmashenko D, Kel A, et al.

(5) Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome AnalysisInternational journal of molecular sciencesJanuary 27, 2020Orekhov AN, Nikiforov NG, Sukhorukov VN, Kubekina MV, Sobenin IA, Wu WK, Foxx KK, Pintus S, Stegmaier P, Stelmashenko D, et al.

(6) Organic dust induces inflammatory gene expression in lung epithelial cells via ROS-dependent STAT-3 activationAmerican journal of physiology. Lung cellular and molecular physiologyJuly 1, 2019Natarajan K, Meganathan V, Mitchell C, Boggaram V.STAT-3 (sc-29493), EGFR (sc-29301), TYK2 (sc-36764), protease-activated receptor 1 (PAR-1; sc-36663), and PAR-2 (sc-36188) were obtained from Santa Cruz Biotechnology and dissolved in autoclaved water. Dust extract preparation.

(7) Factor VII-Induced MicroRNA-135a Inhibits Autophagy and Is Associated with Poor Prognosis in Hepatocellular CarcinomaMolecular therapy. Nucleic acidsDecember 15, 2017Huang KT, Kuo IY, Tsai MC, Wu CH, Hsu LW, Chen LY, Kung CP, Cheng YF, Goto S, Chou YW, et al.miRNAs Transient transfection of siRNAs against TF (sc-44984, Santa Cruz Biotechnology), FVII (sc-40401), PAR-2 (sc-36188), or miR-135a mimic (Thermo Fisher Scientific) was conducted in Hep3B cells in 6-well plates using GenMute siRNA transfection reagent

(8) Proteases and oxidant stress control organic dust induction of inflammatory gene expression in lung epithelial cellsRespiratory researchOctober 22, 2016Natarajan K, Gottipati KR, Berhane K, Samten B, Pendurthi U, Boggaram V.

(9) Trefoil factor 3 (TFF3) from human breast milk activates PAR-2 receptors, of the intestinal epithelial cells HT-29, regulating cytokines and defensinsBratislava Medical JournalAugust 23, 2016G. J. Barrera, G. Sanchez Tortoleronm. NA-interference Assay siRNAs targeting PAR-2 and PAR-1 were from Santa Cruz Biotechnology (cat. No. sc-36188, and cat. No. sc-36663). HT29 cells were cultured at 250,000 cells/ml in DMEM with 10 % FBS in 25 cm2

(10) A protease-activated receptor 2 agonist (AC-264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages: Role of p53Cell biology internationalJune 1, 2016Yamaguchi R, Yamamoto T, Sakamoto A, Ishimaru Y, Narahara S, Sugiuchi H, Yamaguchi Y.

(11) Silencing of protease-activated receptors attenuates synovitis and cartilage damage following a joint bleed in haemophilic miceHaemophilia : the official journal of the World Federation of HemophiliaJanuary 1, 2016Nieuwenhuizen L, Schutgens RE, Coeleveld K, Mastbergen SC, Schiffelers RM, Roosendaal G, Biesma DH, Lafeber FP.

(12) Cytokine responses induced by diesel exhaust particles are suppressed by PAR-2 silencing and antioxidant treatment, and driven by polar and non-polar soluble constituentsToxicology lettersOctober 14, 2015Bach N, Bølling AK, Brinchmann BC, Totlandsdal AI, Skuland T, Holme JA, Låg M, Schwarze PE, Øvrevik J.

(13) Proteases in agricultural dust induce lung inflammation through PAR-1 and PAR-2 activationAmerican journal of physiology. Lung cellular and molecular physiologyAugust 15, 2015Romberger DJ, Heires AJ, Nordgren TM, Souder CP, West W, Liu XD, Poole JA, Toews ML, Wyatt TA.

(14) MDA-9/syntenin is essential for factor VIIa-induced signaling, migration, and metastasis in melanoma cellsThe Journal of biological chemistryFebruary 6, 2015Aissaoui H, Prévost C, Boucharaba A, Sanhadji K, Bordet JC, Négrier C, Boukerche H.

(15) Thromboxane A2 receptor-mediated release of matrix metalloproteinase-1 (MMP-1) induces expression of monocyte chemoattractant protein-1 (MCP-1) by activation of protease-activated receptor 2 (PAR2) in A549 human lung adenocarcinoma cellsMolecular carcinogenesisAugust 1, 2014Li X, Tai HH.

(16) Interconnections between autophagy and the coagulation cascade in hepatocellular carcinomaCell death & diseaseMay 22, 2014Chen KD, Wang CC, Tsai MC, Wu CH, Yang HJ, Chen LY, Nakano T, Goto S, Huang KT, Hu TH, et al.experimental condition. siRNA transfection siRNAs directed against TF (sc-44984), FVII (sc-40401), PAR-2 (sc-36188) and mTOR (sc-35409) mRNAs were obtained from Santa Cruz Biotechnology Inc. Transient transfection of

(17) Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cellsRespiratory researchFebruary 18, 2014Nomura K, Obata K, Keira T, Miyata R, Hirakawa S, Takano K, Kohno T, Sawada N, Himi T, Kojima T.[28,29]. Transfection with small interfering RNA (siRNA) siRNA duplex oligonucleotides against human PAR 2 (sc-36188) were synthesized by Santa Cruz Biotechnology, inc. (Santa Cruz, CA). The hTERT-transfected HNECs at

(18) Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activationCellular microbiologyJanuary 1, 2014Inaba H, Sugita H, Kuboniwa M, Iwai S, Hamada M, Noda T, Morisaki I, Lamont RJ, Amano A.

(19) Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane SCF and the PAR-2/PKC-α/Raf-1/p44/42 signaling pathwayThe American journal of pathologyJune 1, 2013Wygrecka M, Dahal BK, Kosanovic D, Petersen F, Taborski B, von Gerlach S, Didiasova M, Zakrzewicz D, Preissner KT, Schermuly RT, et al.

(20) Chymase-mediated intestinal epithelial permeability is regulated by a protease-activating receptor/matrix metalloproteinase-2-dependent mechanismAmerican journal of physiology. Gastrointestinal and liver physiologyMarch 1, 2013Groschwitz KR, Wu D, Osterfeld H, Ahrens R, Hogan SP.

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PAR-2 siRNA (h)

PAR-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PAR-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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