PERK siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPERK siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36213
Gene Nameeukaryotic translation initiation factor 2-alpha kinase 3
Quantity10 µM
Specieshuman
NCBI Full Gene Nameeukaryotic translation initiation factor 2 alpha kinase 3
NCBI Gene AliasesPEK, PERK, WRS
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axisJournal of Advanced ResearchSeptember 1, 2025Xige Zhang, Yazheng Wang, Jinjin Wang, Yang Zhang, Rui Li, Xiaoyu Wang, Xiaotong Ge, Qingyuan Ye, Jiyun Ji, Dongdong Fei, et al.h. The OPDLSCs in the experimental group were transfected with 50 nM PERK (Santa Cruz Biotechnology, sc-36213, CA, USA), IRE1α (Santa Cruz Biotechnology, sc-40705), and ATF6 small interfering RNA (siRNA) (Genechem,

(2) Inhibition of the Integrated stress response by Epstein-Barr virus oncoprotein LMP1 attenuates epithelial cell differentiation and lytic viral reactivationPLoS PathogFebruary 14, 2025Deo R. Singh, Yitao Zhang, Sophia J. White, Scott E. Nelson, Stuart A. Fogarty, Abigail S. Pawelski, Alisha S. Kansra, Shannon C. Kenneyharvesting for western blot analysis. siRNAs siRNAs against KLF4 (sc-35437), BLIMP1 (sc-37714), PERK (sc-36213), GCN2 (sc-45644), ATF4 (sc-35112), and control siRNAs A and C (sc-37007, sc-44230) were purchased from

(3) Fragility of ER homeostatic regulation underlies haploid instability in human somatic cellsJournal of Biological ChemistryNovember 1, 2024Sumire Ishida-Ishihara, Kan Yaguchi, Sena Miura, Ryoto Nomura, QiJiao Wang, Koya Yoshizawa, Kimino Sato, Guang Yang, Krisztina Veszelyi, Gabor Banhegyi, et al.lowercase). siRNAs targeting ATF6α or PERK were purchased from Santa Cruz Biotechnology (sc-37699 or sc-36213, respectively). siRNA transfection was performed using Lipofectamine RNAiMAX (Thermo Fisher Scientific). Flow cytometry

(4) Paeoniflorin Induces ER Stress-Mediated Apoptotic Cell Death by Generating Nox4-Derived ROS under Radiation in Gastric CancerNutrientsDecember 13, 2023Tae Woo Kim(double-stranded siRNAs; 30 nmol/mL, Santa Cruz) to target PERK (Bioneer; 1649-1), CHOP (Santa Cruz; sc-36213), Nox4 (Santacruz), and GRP78 (Santa Cruz; sc-29338) using Lipofectamine 2000 (Invitrogen, Carlsbad,

(5) Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver CancerInternational journal of molecular sciencesMay 22, 2023Kim TW.Cruz, Dallas, TX, USA) targeting CHOP (Bioneer; 1649-1, Daejeon, Republic of Korea), PERK (Santa Cruz; sc-36213), and GRP78 (Santa Cruz; sc-29338) for 24 h using Lipofectamine 2000 reagent (Invitrogen, Carlsbad,

(6) Targeting ER Stress with Saikosaponin A to Overcome Resistance under Radiation in Gastric Cancer CellsInternational journal of molecular sciencesMarch 16, 2023Kim TW.double-stranded siRNAs (30 nmol/mL, Santa Cruz) against GRP78 (Santa Cruz; sc-29338), PERK (Santa Cruz; sc-36213), Nox4 (Santa Cruz; sc-41586), and CHOP (Bioneer; 1649-1) and shRNAs against PERK (Santa Cruz; sc-36213-SH)

(7) Nodakenin Induces ROS-Dependent Apoptotic Cell Death and ER Stress in Radioresistant Breast CancerAntioxidants (Basel, Switzerland)February 15, 2023Kim TW.

(8) BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1iScienceDecember 22, 2022Hromas R, Srinivasan G, Yang M, Jaiswal A, Totterdale TA, Phillips L, Kirby A, Khodayari N, Brantley M, Williamson EA, et al.

(9) Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 moduleiScienceMay 20, 2022Patel S, Kumar S, Baldan S, Hesin A, Yaglom J, Sherman MY.siRNA no. 5, BAG3 (D-011957-01), GCN2 (D-016634-02), DDIT3 (M-017609-01), HRI (M-006968-00) , siPERK (sc-36213) and siPKR (sc-36263) from Santa Cruz, see also Table S3. Real time PCR analysis Total RNA was isolated

(10) PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathwayRedox biologyApril 1, 2022Lee DH, Park JS, Lee YS, Bae SH.transfection GFP-LC3B HeLa cells were transfected with siRNAs targeting PERK (20 nM, Santa Cruz Biotechnology; sc-36213) or control siRNA (20 nM, Bioneer; SP-1011). Hepa1c1c7 cells were transfected with siRNAs targeting

(11) Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cellsActa pharmacologica SinicaMarch 1, 2022Kim TW.

(12) Endoplasmic Reticulum Stress Contributed to Dipyridamole-Induced Impaired Autophagic Flux and Glioma ApoptosisInternational journal of molecular sciencesJanuary 6, 2022Chang CY, Wu CC, Wang JD, Liao SL, Chen WY, Kuan YH, Wang WY, Chen CJ.

(13) TXNIP Links Anticipatory Unfolded Protein Response to Estrogen Reprogramming Glucose Metabolism in Breast Cancer CellsEndocrinologyJanuary 1, 2022Wang Y, Chen S.

(14) Schweinfurthin induces ICD without ER stress and caspase activationOncoimmunologyJanuary 1, 2022Zhang R, Neighbors JD, Schell TD, Hohl RJ.

(15) PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cellsCell death & diseaseNovember 1, 2021Sheshadri N, Poria DK, Sharan S, Hu Y, Yan C, Koparde VN, Balamurugan K, Sterneck E.5′-rCrUrGrUrUrGrArArGrArGrGrUrCrGrGrCrGrATT-3′ siRNA pools for ATF6A/ATF6α (sc-37699), ERN1/IRE1α (sc-40705), EIF2AK3/PERK (sc-36213), NRF2 (sc-37030) and STAT3 (sc-29493) were purchased from Santa Cruz Biotechnology. RNA isolation

(16) PB01 suppresses radio-resistance by regulating ATR signaling in human non-small-cell lung cancer cellsScientific reportsJune 8, 2021Kim TW, Hong DW, Hong SH.

(17) DIM-C-pPhtBu induces lysosomal dysfunction and unfolded protein response - mediated cell death via excessive mitophagyCancer lettersApril 28, 2021Kang SU, Kim DH, Lee YS, Huang M, Byeon HK, Lee SH, Baek SJ, Kim CH.

(18) Nuclear factor-kappa B signaling in endometriotic stromal cells is not inhibited by progesterone owing to an aberrant endoplasmic reticulum stress response: a possible role for an altered inflammatory process in endometriosisMolecular human reproductionFebruary 5, 2021Choi J, Jo M, Lee E, Lee DY, Choi D.

(19) Protease Inhibitor Anti-HIV, Lopinavir, Impairs Placental Endocrine FunctionInternational journal of molecular sciencesJanuary 12, 2021Fraichard C, Bonnet-Serrano F, Laguillier-Morizot C, Hebert-Schuster M, Lai-Kuen R, Sibiude J, Fournier T, Cohen M, Guibourdenche J.

(20) CB13, a novel PPARγ ligand, overcomes radio-resistance via ROS generation and ER stress in human non-small cell lung cancerCell death & diseaseOctober 13, 2020Kim TW, Hong DW, Hong SH.

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PERK siRNA (h)

PERK siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PERK siRNA (h) from Santa Cruz Biotechnology, Inc.

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