p21 Waf1/Cip1 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemp21 Waf1/Cip1 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29428
Gene Namecyclin-dependent kinase inhibitor 1A (p21, Cip1)
Quantity10 µM
Speciesmouse
NCBI Full Gene Namecyclin dependent kinase inhibitor 1A (P21)
NCBI Gene AliasesCAP20, CDKI, CIP1, Cdkn1, P21, SDI1, Waf1, mda6, p21Cip1, p21WAF
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signalingbioRxivMay 25, 2025Kanako Iwasaki, Priscila Carapeto, Cristian Abarca, Francesko Hela, Stephanie Sanjines, Sebastian Pena, Sandra Le, Hui Pan, Christopher Cahill, Ayush Midha, et al.reagent (Invitrogen Waltham, MA; Lot:2538674) and p21Cip1 (Santa Cruz Biotechnology Inc., Dallas, TX; sc:29428) at 50 nM according to the manufacturer’s instructions and incubated for 5 minutes at room temperature.

(2) p21 Improving Osteoarthritis by Regulating the Pyroptosis of Cartilage CellsIranian Journal of Public HealthMarch 13, 2024Xiao Ouyang, Xingran Chen, Feng Xin, Peng Sha, Songming Tong, Meng Liu, Shimin Li, Xinxin Liits negative control (Negative control, NC) were purchased from Santa cruz biotechnology (Cargo No.: sc-29428, USA), with NC sequences CUACAACAGCCACAACGUCdTdT. The transfection operation was conducted according

(3) LncRNA TUG regulates osteogenic differentiation of bone marrow mesenchymal stem cells via miRNA-204/SIRT 1J Musculoskelet Neuronal InteractSeptember 1, 2022Xiao Ouyang, Yunzhi Ding, Li Yu, Feng Xin, Xiaowei Yangsh-NC, sh-TUG1, miR-204-NC, miR204, AMO-204, AMO-NC (Santa Cruz technology, TX, USA; Cargo Number: sc-29428, USA), the transfection was operated according to the product instruction. After 6 h of transfection,

(4) Metformin: a novel promising option for fertility preservation during cyclophosphamide-based chemotherapyMolecular human reproductionJanuary 22, 2021Huang CC, Chou CH, Yang YS, Ho HN, Shun CT, Wen WF, Chen SU, Chen MJ.other experiments. The targeted siRNAs for p21, p53 and control were from Santa Cruz Biotechnology; sc-29428, sc-29436 and sc-36869, respectively. The request for siRNA sequences was declined by Santa Cruz. Statistical

(5) Prophylaxis of Diallyl Disulfide on Skin Carcinogenic Model via p21-dependent Nrf2 stabilizationScientific reportsOctober 19, 2016Shan Y, Wei Z, Tao L, Wang S, Zhang F, Shen C, Wu H, Liu Z, Zhu P, Wang A, et al.

(6) NGF promotes mouse granulosa cell proliferation by inhibiting ESR2 mediated down-regulation of CDKN1AMolecular and cellular endocrinologyMay 5, 2015Wang Y, Liu W, Du J, Yu Y, Liang N, Liang M, Yao G, Cui S, Huang H, Sun F.

(7) MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G₁/S transition and apoptosis by targeting p21(WAF1/CIP1)British Journal of CancerJuly 15, 2014H Wang, L-J Zhu, Y-C Yang, Z-X Wang, R Wangoligonucleotides (anti-miR-NC or miR-NC mimics) were obtained from Ambion Inc. (Austin, TX, USA). siRNA/p21 (sc-29428) (Santa Cruz Biotechnology, Santa Clara, CA, USA) or siRNA/control was purchased from Santa Cruz Inc.

(8) The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expressionPLoS ONEOctober 14, 2013Zhili Liu, Ming Sun, Kaihua Lu, Jing Liu, Meiling Zhang, Weiqin Wu, Wei De, Zhaoxia Wang, Rui Wang5’-UUUUCUACCAGGUCGGUAC-3’; siRNA/HOTAIR2: 5’- AAUUCUUA- AAUUGGGCUGG-3’) (GenePharma, Shanghai, China) or siRNA/p21 (sc-29428) (Santa cruz biotechnology, USA) or siRNA/control (5’-CUACAACAGCCACAACGUCdTdT-3’) using Lipofectamine

(9) Inactivation of p27kip1 promotes chemical hepatocarcinogenesis through enhancing inflammatory cytokine secretion and STAT3 signaling activationJournal of cellular physiologyOctober 1, 2013Guo J, Ma Q, Zhou X, Fan P, Shan T, Miao D.

(10) Disruption of the p53-p21 pathway inhibits efficiency of the lytic-replication cycle of herpes simplex virus type 2 (HSV-2)Virus researchOctober 1, 2012Zhou Q, Zhu M, Zhang H, Yi T, Klena JD, Peng Y.

(11) Microphthalmia-associated transcription factor is required for mature myotube formationBiochimica et biophysica actaFebruary 1, 2012Ooishi R, Shirai M, Funaba M, Murakami M.-3' for Mitf-A, 5'-CCUUAGUGCUCUUCCGAAAGA-3' 5'-UUUCGGAAGAGCACUAAGGUU-3' 5’-GGUUACGUCCAGGAGCGCATT-3’ for Itga9, and and and 5'-UGCGCUCCUGGACGUAGCCTT-3' for GFP. The siRNA for p21 was purchased (sc-29428; Santa Cruz Biotechnology). An equal amount of the oligonucleotide was mixed for each gene to prepare

(12) T lymphocyte proliferation is suppressed by the opioid growth factor ([Met(5)]-enkephalin)-opioid growth factor receptor axis: implication for the treatment of autoimmune diseasesImmunobiologyMay 1, 2011Zagon IS, Donahue RN, Bonneau RH, McLaughlin PJ.

(13) Endothelial FGF receptor signaling accelerates atherosclerosisAmerican journal of physiology. Heart and circulatory physiologyJanuary 1, 2011Che J, Okigaki M, Takahashi T, Katsume A, Adachi Y, Yamaguchi S, Matsunaga S, Takeda M, Matsui A, Kishita E, et al.

(14) Revelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathwayThe Journal of biological chemistryMarch 26, 2010Li DQ, Pakala SB, Reddy SDN, Ohshiro K, Peng SH, Lian Y, Fu SW, Kumar R.

(15) p21 is required for atRA-mediated growth inhibition of MEPM cells, which involves RARJournal of cellular biochemistryAugust 15, 2008Yu Z, Li W, Lu Q, Wang L, Zhang X, Han P, Chen P, Pei Y.

(16) The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanomaJournal of cellular biochemistryNovember 1, 2007Hahm E, Jin DH, Kang JS, Kim YI, Hong SW, Lee SK, Kim HN, Jung DJ, Kim JE, Shin DH, et al.

(17) Basic helix-loop-helix protein E47-mediated p21Waf1/Cip1 gene expression regulates apoptosis of intestinal epithelial cellsThe Biochemical journalOctober 15, 2007Bhattacharya S, Guo H, Ray RM, Johnson LR.antibody, Protein A–agarose and Protein G–agarose conjugates, p21Cip1 siRNA (small interfering RNA) (sc-29428) and E47-specific siRNA (sc-35252) were all obtained from Santa Cruz Biotechnology. TRIzol RNA extraction

(18) HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cellsThe Journal of cell biologySeptember 25, 2006Zeng L, Xiao Q, Margariti A, Zhang Z, Zampetaki A, Patel S, Capogrossi MC, Hu Y, Xu Q.viruses were used as controls, respectively. siRNA knockdown The siRNAs for p53(sc-29436) and p21(sc-29428) were purchased from Santa Cruz Biotechnology, Inc. The control siRNA and the siRNA for HDAC3 (5′-ccucaucgccuggcauugatt-3′

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