Notch 3 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNotch 3 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37135
Gene Namenotch 3
Quantity10 µM
Specieshuman
NCBI Full Gene Namenotch receptor 3
NCBI Gene AliasesCADASIL, CADASIL1, CASIL, IMF2, LMNS
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Prolyl-isomerase Pin1 drives platinum resistance by regulating Notch3 stability and function in ovarian cancerJournal of Experimental & Clinical Cancer ResearchFebruary 11, 2026Maria Valeria Giuli, Angelica Mancusi, Bianca Natiello, Samuele Di Cristofano, Rebecca Reali, Maria Gemma Pignataro, Daniel D’Andrea, Laura Di Magno, Carmine Nicoletti, Alessandra Giorgi, et al.protocols. For RNA interference, the cells were transfected with siRNA-Ctrl (#sc-37007), siRNA-Notch3 (#sc-37135), or siRNA-Pin1 (#sc-36230) (Santa Cruz Biotechnology, Dallas, TX, USA) for 72 h. Unless otherwise specified,

(2) Endothelial cell senescence exacerbates pulmonary hypertension by inducing juxtacrine Notch signaling in smooth muscle cellsiScienceMay 19, 2023Ramadhiani R, Ikeda K, Miyagawa K, Ryanto GRT, Tamada N, Suzuki Y, Kirita Y, Matoba S, Hirata KI, Emoto N.

(3) NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathwayOncogeneMarch 1, 2021Kang W, Zhang J, Huang T, Zhou Y, Wong CC, Chan RCK, Dong Y, Wu F, Zhang B, Wu WKK, et al.

(4) Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein responseOncogenesisOctober 18, 2020Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, et al.and #2) for each human gene: from Santa Cruz Biotechnology (Santa Cruz, Dallas, TX, USA), siN3 #1 (sc-37135), siN1 #1 (sc-36095), and corresponding control scrambled siRNAs #1 (sc-37007); from ThermoFisher Scientific

(5) Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagationOncogeneDecember 1, 2018Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese AF, Noce C, Ciuffetta A, Vacca A, Besharat ZM, Bellavia D, et al.#42196). siRNA silencing experiments TALL-1 cells were transfected with 200 nM siRNAs anti-Notch3 (Santa-Cruz, sc-37135) or (Dharmacon, s1623) and their corresponding control scrambled siRNAs (Santa-Cruz, sc-37007 and Dharmacon,

(6) NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrestOncogenesisMay 25, 2018Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, et al.silencing Cell were transfected as previously described61 with siRNAs anti-Notch3 (Catalog number sc-37135), Notch1 (Catalog number sc-36095), and corresponding control scrambled siRNAs (Catalog number sc-37007),

(7) Notch3 expression correlates with thyroid cancer differentiation, induces apoptosis, and predicts disease prognosisCancerMarch 1, 2017Somnay YR, Yu XM, Lloyd RV, Leverson G, Aburjania Z, Jang S, Jaskula-Sztul R, Chen H.using 150 nM of either a gene-specific small interfering RNA (siRNA) against NOTCH3(h) (catalog no. sc-37135, Santa Cruz Biotechnology, Dallas, TX, USA) or nonspecific-siRNA (catalog no. sc-37007, Santa Cruz Biotechnology)

(8) Association between high levels of Notch3 expression and high invasion and poor overall survival rates in pancreatic ductal adenocarcinomaOncology reportsNovember 1, 2016Zhou JX, Zhou L, Li QJ, Feng W, Wang PM, Li EF, Gong WJ, Kou MW, Gou WT, Yang YL.

(9) Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progressionOncogeneSeptember 8, 2016Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, et al.mRNA. siRNA silencing Cells were transfected with 20 nM siRNAs anti-Notch3 (Santa Cruz Biotechnology; Cat#sc-37135) or Pin1 (Santa Cruz Biotechnology; Cat#sc-36230) and the corresponding control scrambled siRNAs (Santa Cruz Biotechnology

(10) Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological inductionMolecular cancer therapeuticsFebruary 1, 2015Jaskula-Sztul R, Eide J, Tesfazghi S, Dammalapati A, Harrison AD, Yu XM, Scheinebeck C, Winston-McPherson G, Kupcho KR, Robers MB, et al.

(11) Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemiaLeukemiaDecember 1, 2014Kumar V, Palermo R, Talora C, Campese AF, Checquolo S, Bellavia D, Tottone L, Testa G, Miele E, Indraccolo S, et al.N1IC,32 RBPjk and MAM,33 p6534 and C/EBPa.35 Transient transfection of Jurkat cells, with siNotch3 (sc-37135; SCBT, Santa Cruz B., Santa Cruz, CA, USA) and its control (AM4611; Ambion), was carried out with Amaxa-Nucleofection

(12) The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinomaPloS oneJanuary 1, 2013Zhou L, Zhang N, Song W, You N, Li Q, Sun W, Zhang Y, Wang D, Dou K.

(13) Density of human bone marrow stromal cells regulates commitment to vascular lineagesStem cell researchMay 1, 2011Whyte JL, Ball SG, Shuttleworth CA, Brennan K, Kielty CM.knockdown (Qiagen). For Notch knockdowns, siRNAs for Notch1 (sc-36095), Notch2 (sc-40135), and Notch3 (sc-37135) (Santa Cruz, USA) were employed, with scrambled siRNA as a control (Qiagen). Immunoprecipitation analysis Cell

(14) Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancerBreast cancer research and treatmentAugust 1, 2010Cohen B, Shimizu M, Izrailit J, Ng NF, Buchman Y, Pan JG, Dering J, Reedijk M.

(15) Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinomaOncotargetJanuary 1, 0001"Capaccione KM, Hong X, Morgan KM, Liu W, Bishop JM, Liu L, Markert E, Deen M, Minerowicz C, Bertino JR, et al."post-transfection. siRNA oligos were obtained from Santa Cruz (siNotch1- sc-36095; siNotch2- sc-40137; siNotch3- sc-37135; siNotch4- sc-40135; siSox9- sc-36533; scr- sc-37007; FITC-A- sc-36869). Plasmid transfections were

(16) Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancerInternational journal of cancerJanuary 1, 0001"Danza G, Di Serio C, Ambrosio MR, Sturli N, Lonetto G, Rosati F, Rocca BJ, Ventimiglia G, del Vecchio MT, Prudovsky I, et al."

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Notch 3 siRNA (h)

Notch 3 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Notch 3 siRNA (h) from Santa Cruz Biotechnology, Inc.

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