SREBP-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSREBP-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36557
Gene Namesterol regulatory element binding transcription factor 1
Quantity10 µM
Specieshuman
NCBI Full Gene Namesterol regulatory element binding transcription factor 1
NCBI Gene AliasesHMD, IFAP2, SREBP1, bHLHd1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolismJournal of translational medicineMarch 16, 2023Lou B, Wu H, Ott H, Bennewitz K, Wang C, Poschet G, Liu H, Yuan Z, Kroll J, She J.

(2) Suppression of SREBP-1 Expression by Simvastatin Decreases Visfatin-Induced Chemoresistance to Sunitinib in Human Renal Carcinoma 786-O CellsLife (Basel, Switzerland)November 15, 2022Chen TC, Huang CW, Lo CY, Chen CN, Chang SF, Chen YY.SREBP-1 (sc-13551, 1:1000 dilution), the non-targeting siRNA (sc-37007) and siRNA for SREBP-1 mRNA (sc-36557) were purchased from Santa Cruz (Dallas, TX, USA). Protein kinase inhibitors (LY294002 for Akt and rapamycin

(3) Apelin-mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesisCancer scienceNovember 1, 2022Zhu Y, Yang Y, Bu H, Huang H, Chen H, Ran J, Qin L, Ni Y, Yao M, Song T, et al.construction and RNAi transfection All plasmids were constructed by Genecopoeia. siRNAs targeting SREBP1 (sc‐36557) and HMGA1 (sc‐37115) were purchased from Santa Cruz. The siRNA against CAD and APJ were designed and

(4) GDNF regulates lipid metabolism and glioma growth through RET/ERK/HIF‑1/SREBP‑1International journal of oncologySeptember 1, 2022Yu Z, Li H, Wang M, Luo W, Xue Y.factor 1 (HIF-1) siRNA (cat. no. sc-35561; Santa Cruz Biotechnology, Inc.), SREBP-1 siRNA (cat. no. sc-36557; Santa Cruz Biotechnology, Inc.) and control siRNA (cat. no. sc-37007; Santa Cruz Biotechnology, Inc.)

(5) LXRα Regulates oxLDL-Induced Trained Immunity in MacrophagesInternational journal of molecular sciencesMay 31, 2022Findeisen HM, Voges VC, Braun LC, Sonnenberg J, Schwarz D, Körner H, Reinecke H, Sohrabi Y.Cruz, Dallas, TX, USA, #sc- 38828), LXRβ (Santa Cruz, #sc-45316), SREBP1 (Santa Cruz, Dallas, TX, USA, #sc-36557), SREBP2 (Santa Cruz, Dallas, TX, USA, #sc-36559) or Scramble RNA (Santa Cruz, Dallas, TX, USA, #sc-37007)

(6) Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular functionNature communicationsApril 4, 2022Hinden L, Ahmad M, Hamad S, Nemirovski A, Szanda G, Glasmacher S, Kogot-Levin A, Abramovitch R, Thorens B, Gertsch J, et al.USA). Small interfering RNA treatment Small interfering RNA (siRNA) transfection against SREBP1 (sc-36557, Santa Cruz) was performed in hRPTCs using the siRNA reagent system (sc-45064, Santa Cruz) according

(7) Cell suspension culture extract of Eriobotrya japonica attenuates growth and induces apoptosis in prostate cancer cells via targeting SREBP-1/FASN-driven metabolism and ARPhytomedicine : international journal of phytotherapy and phytopharmacologyDecember 1, 2021Hsieh PF, Jiang WP, Basavaraj P, Huang SY, Ruangsai P, Wu JB, Huang GJ, Huang WC.

(8) Induction of SREBP1 degradation coupled with suppression of SREBP1-mediated lipogenesis impacts the response of EGFR mutant NSCLC cells to osimertinibOncogeneDecember 1, 2021Chen Z, Yu D, Owonikoko TK, Ramalingam SS, Sun SY.intensities were quantified by NIH ImageJ software. Gene knockdown with siRNA or shRNA. SREBP1 siRNA (sc-36557) was purchased from Santa Cruz Biotechnology. The procedures used for transfection, as well as the details

(9) LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human MonocytesFrontiers in immunologyJanuary 1, 2020Sohrabi Y, Sonntag GVH, Braun LC, Lagache SMM, Liebmann M, Klotz L, Godfrey R, Kahles F, Waltenberger J, Findeisen HM.were transfected with final concentrations of 60 nM small interfering RNA for SREBP1 (Santa Cruz, # sc-36557) for 24 h using Viromer technology according to the manufacturer’s protocol (Viromer Green, Lipocalyx).

(10) Free Fatty Acids Rewire Cancer Metabolism in Obesity-Associated Breast Cancer via Estrogen Receptor and mTOR SignalingCancer researchMay 15, 2019Madak-Erdogan Z, Band S, Zhao YC, Smith BP, Kulkoyluoglu-Cotul E, Zuo Q, Santaliz Casiano A, Wrobel K, Rossi G, Smith RL, et al.

(11) Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acidLipids in health and diseaseApril 6, 2019Bai XP, Dong F, Yang GH, Zhang L.

(12) CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK PathwayJournal of virologyDecember 15, 2018Wang L, Xie W, Zhang L, Li D, Yu H, Xiong J, Peng J, Qiu J, Sheng H, He X, et al.(sc-29487), MEK1/2 siRNA (sc-29396 and sc-35905), ERK1/2 siRNA (sc-29307 and sc-35335), and SREBP1 siRNA (sc-36557). Quantitative RT-PCR. Total cellular RNA was extracted from cells with RNAiso Plus (TaKaRa) and reverse

(13) Expression of fatty acid synthase is regulated by PGC‑1α and contributes to increased cell proliferationOncology reportsDecember 1, 2017Yun SH, Shin SW, Park JI.PGC-1α was designed by Qiagen (GS10891; Valencia, CA, USA). The Sp1 siRNA (SC-29487) and SREBP-1c siRNA (SC-36557) were purchased from Santa Cruz Biotechnology. The cells were resuspended in PBS at a density of 1.3x107

(14) Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver diseaseBiochimica et biophysica acta. Molecular and cell biology of lipidsSeptember 1, 2017Lin Y, Ding D, Huang Q, Liu Q, Lu H, Lu Y, Chi Y, Sun X, Ye G, Zhu H, et al.

(15) Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney diseaseThe international journal of biochemistry & cell biologyOctober 1, 2016Du C, Wu M, Liu H, Ren Y, Du Y, Wu H, Wei J, Liu C, Yao F, Wang H, et al.

(16) p53 regulates the mevalonate pathway in human glioblastoma multiformeCell death & diseaseOctober 15, 2015Laezza C, D'Alessandro A, Di Croce L, Picardi P, Ciaglia E, Pisanti S, Malfitano AM, Comegna M, Faraonio R, Gazzerro P, et al.Institute (Kenilworth, NJ, USA), was used at 10 μM for 24 h of treatment. siRNA targeting SREBP1 (h) (sc36557) was purchased from Santa Cruz Biotechnology (Dallas, TX, USA). siRNA p53 (106141), SREBP2 (s27) and

(17) HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN PathwayJournal of cellular biochemistryOctober 1, 2015Gao LL, Li M, Wang Q, Liu SA, Zhang JQ, Cheng J.

(18) Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding ProteinsPloS oneJanuary 1, 2015Ochiai A, Miyata S, Shimizu M, Inoue J, Sato R.5′-GGAGGGGTAGGGCCAACGGCCT–3′ and 5′-CATGTCTTCGAAAGTGCAATCC–3′, respectively. siRNA experiments SREBP–1 (sc–36557) and SREBP–2 (sc–36559) siRNAs were obtained from Santa Cruz, and control siRNA (pGL2 luciferase) was

(19) Endothelial cellular senescence is inhibited by liver X receptor activation with an additional mechanism for its atheroprotection in diabetesProceedings of the National Academy of Sciences of the United States of AmericaJanuary 21, 2014Hayashi T, Kotani H, Yamaguchi T, Taguchi K, Iida M, Ina K, Maeda M, Kuzuya M, Hattori Y, Ignarro LJ.

(20) Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemiaDiabetesFebruary 1, 2013Chu X, Liu L, Na L, Lu H, Li S, Li Y, Sun C.

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SREBP-1 siRNA (h)

SREBP-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SREBP-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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