p53 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemp53 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29435
Gene Nametumor protein p53
Quantity10 µM
Specieshuman
NCBI Full Gene Nametumor protein p53
NCBI Gene AliasesBCC7, BMFS5, LFS1, P53, TRP53
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Human respiratory syncytial virus regulates the expression of interferon-stimulated genes through modulation of fibrillarinFront Cell Infect MicrobiolApril 15, 2026José Manuel Ulloa-Aguilar, Victor Javier Cruz-Holguin, Yazmín Rocío Benítez-Zeferino, Edgar Rodrigo Guzmán-Bautista, Julio García-Cordero, Luis Adrián De Jesús-González, Julio Angel Vázquez-Martínez, Edgar Ricardo Vázquez-Martínez, Luis Herrera-Moro Huitron, Alfredo Mosqueda-Gracida, et al.(siRNA) targeting FBL (Thermo Fisher Scientific #s4820), siRNA targeting p53 (Santa Cruz Biotechnology, #sc-29435), or a scrambled siRNA control (Thermo Fisher Scientific #4390843) using Lipofectamine™ 2000 reagent,

(2) Rewiring melanoma cell fate: TRPM8 modulators trigger apoptosis and boost NK cell cytotoxicityCell Death & DiseaseFebruary 14, 2026Carmela Sorrentino, Carmine Lauretta, Rosa D’Angiolo, Simona Musella, Pia Giovannelli, Alessia Bertamino, Carmine Ostacolo, Isabel Gomez Monterrey, Antimo Migliaccio, Gabriella Castoria, et al.silencing and transfection Small interfering RNAs (siRNAs) targeting human TRPM8 (sc-95009) and TP53 (sc-29435) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA) and transfected into melanoma cells

(3) FGF 13 functions as a regulator of the ERK/aerobic glycolysis axis in the inflammatory state during septic lung injuryNature CommunicationsFebruary 5, 2026Junjie Zhu, Jiaqi Wang, Chunhui Jiang, Jie Wang, Jie Zhou, Gaozan Tong, Yuecheng Wu, Zhuoyao Ou, Junbo Ye, Enzhao Shen, et al.qRT-PCR. RNA Interference in HPMECs and THP-1 cells The Si-Scramble or Si-p53 (Santa Cruz Biotechnology, sc-29435) was mixed with Lipofectamine 2000 in Opti-MEM (Gibco, 51985034) and incubated for 20 min at 37 °C.

(4) Analysis of human endogenous retrovirus in hepatocellular carcinomas using HERV-FcountBMC MicrobiolOctober 2, 2025Ya-Sian Chang, Ming-Hon Hsu, Chin-Chun Chung, I-Lu Lai, Ya-Ting Lee, Ju-Chen Yen, Chieh-Min Chang, Ta-Chih Liu, Jan-Gowth Changcells. The processes were as our previous study [37]. To perform TP53 knockdown, the siRNA for p53 (sc-29435) and control was from Santa Cruz Biotechnology (Santa Cruz, CA, USA). HepG2 cells were grown in 6-wells

(5) Cellular adaptations impact the biological activity of naphthalene diimide G-quadruplex ligands in ALT-positive osteosarcoma cellsCell Death DisAugust 1, 2025Joanna Bidzinska, Lorenzo Di Pietro, Eisa Naghshineh, Cecilia Pandini, Filippo Doria, Nadia Zaffaroni, Paolo Gandellini, Stephen Neidle, Marco FoliniMerck Life Science S.r.l.). Target-specific siRNAs designed to silence the expression of TP53 (sip53; sc-29435); CDKN1A (sip21; sc-44214), BLM (siBLM; sc-29808) and NFE2L2 (siNrf2; sc-44332) as well as a control

(6) DRG2 levels in prostate cancer cell lines predict response to PARP inhibitor during docetaxel treatmentInvestig Clin UrolDecember 31, 2024Jeong Min Lee, Won Hyeok Lee, Seung Hyeon Cho, Jeong Woo Park, Hyuk Nam Kwon, Ji Hye Kim, Sang Hun Lee, Ji Hyung Yoon, Sungchan Park, Seong Cheol Kiminstructions. Small interfering RNAs (siRNAs) targeting human DRG2 (siDRG2; sc-93839), human p53 (sip53; sc-29435), and control siRNA (scRNA; sc-37007) were purchased from Santa Cruz Biotechnology. AMC-HN3 cells (1.5

(7) FGF12 Positively Regulates Keratinocyte Proliferation by Stabilizing MDM2 and Inhibiting p53 Activity in PsoriasisAdvanced ScienceOctober 1, 2024Nan Wang, Xiejun Xu, Fangqian Guan, Yifan Lin, Yizhou Ye, Jie Zhou, Jianjun Feng, Sihang Li, Junbo Ye, Zhouhao Tang, et al.Additionally, Fgf12 siRNA (Santa Cruz Biotechnology, sc‐39466), p53 siRNA (Santa Cruz Biotechnology, sc‐29435), MDM2 siRNA (Santa Cruz Biotechnology, sc‐29394), and β‐Trcp siRNA (Santa Cruz Biotechnology, sc‐37178)

(8) Hepatitis B Virus X Protein Induces Reactive Oxygen Species Generation via Activation of p53 in Human Hepatoma CellsBiomoleculesSeptember 24, 2024Seungyeon Kim, Jimin Park, Jiwoo Han, Kyung Lib JangCat No. 003049). Scrambled (SC) short hairpin RNA (shRNA) (Cat No. sc-37007) and p53 shRNA (Cat No. sc-29435) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). The pCMV p53-WT, encoding WT p53,

(9) P53 Status Influences the Anti-proliferative Effect Induced by IFITM1 Inhibition in Estrogen Receptor-positive Breast Cancer CellsCancer Genomics - ProteomicsSeptember 1, 2024DER SHENG SUN, JUNG-SOOK YOON, YONG-SEOK KIM, HYE SUNG WONinterfering RNA (siRNA) transfection. MCF-7 and TamR were transiently transfected with p53 siRNA (#sc-29435, Santa Cruz), IFITM1 siRNA (#sc-44549, Santa Cruz), and negative control siRNA (#sc-37007, Santa Cruz)

(10) Reactive Oxygen Species Induction by Hepatitis B Virus: Implications for Viral Replication in p53-Positive Human Hepatoma CellsInternational Journal of Molecular SciencesJune 15, 2024Yuna Jeong, Jiwoo Han, Kyung Lib JangRNA (shRNA) were acquired from Santa Cruz Biotechnology (Santa Cruz, CA, USA, Cat No. sc-37007 and sc-29435, respectively). The pCMV p53-WT plasmid was a gift from Chang-Woo Lee (Sungkyunkwan University, Suwon,

(11) Trans-amplifying RNA expressing functional miRNA mediates target gene suppression and simultaneous transgene expressionMolecular therapy. Nucleic acidsJune 11, 2024Yıldız A, Hasani A, Hempel T, Köhl N, Beicht A, Becker R, Hubich-Rau S, Suchan M, Poleganov MA, Sahin U, et al.electroporated at 500 V/cm with 1 pulse of 24 ms. Lipofection of cells with p53 siRNA (Santa Cruz, sc29435) or control siRNA (Santa Cruz, sc-37000) were performed using Lipofectamine RNAiMax (Thermo Fisher Scientific)

(12) p53 activation enhances the sensitivity of non-small cell lung cancer to the combination of SH003 and docetaxel by inhibiting de novo pyrimidine synthesisCancer Cell InternationalMay 4, 2024Yu-Jeong Choi, Kangwook Lee, Seo Yeon Lee, Youngbin Kwon, Jaehyuk Woo, Chan-Yong Jeon, Seong-Gyu KoRNAiMAX reagent or Lipofectamine 3000 (Thermo Scientific, USA). p53 siRNA was obtained from Santa Cruz (sc-29435, USA) and p53 plasmid was purchased from Addgene (#69003). The UMPS siRNA (5′-GAGAACCACTTCACTGGTT-3′)

(13) Knockdown of TFAP2E results in rapid G2/M transition in oral squamous cell carcinoma cellsOncology LettersJanuary 29, 2024Ryo Sakai, Kyoko Fujiwara, Eri Nagasaki‑Maeoka, Yoshinori Inagaki, Bin Yamaoka, Eri Muto‑Fujita, Yusuke Kamidaki, Tsugumichi Koshinaga, Shuichiro Uehara, Tadateru Takayama, et al.control siRNA (si-N/C; cat. no. 4390843; Thermo Fisher Scientific, Inc.) and anti-TP53 siRNA (cat. no. sc-29435; Santa Cruz Biotechnology, Inc.) were used in the present study. Analysis of cell proliferation To

(14) All-trans retinoic acid downregulates HBx levels via E6-associated protein-mediated proteasomal degradation to suppress hepatitis B virus replicationPloS oneJanuary 1, 2024Han J, Jang KL.purchased from OriGene (Rockville, MD, USA). Scrambled (SC) shRNA (Cat No. sc-7007), p53 shRNA (Cat No. sc-29435), and E6AP shRNA plasmids were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). pHA-ubiquitin

(15) Hydrogen Peroxide Inhibits Hepatitis B Virus Replication by Downregulating HBx Levels via Siah-1-Mediated Proteasomal Degradation in Human Hepatoma CellsInternational journal of molecular sciencesAugust 28, 2023Yoon H, Lee HK, Jang KL.described [45]. Scrambled (SC) short hairpin RNA (shRNA) (Cat No. sc-37007) and p53 shRNA (Cat No. sc-29435) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Siah-1 shRNA (Cat No. SHCLND-NM003031)

(16) Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via Phosphorylation of p53 Regulated by ER Stress in Hepatocellular CarcinomaCancersAugust 5, 2023Jeon Y, Kim T, Kwon H, Kim JK, Park YT, Ham J, Kim YJ.mRNA expression was analyzed using RT-PCR. 2.12. siRNA-Mediated Knockdown Experiments p53 (siRNAs; sc-29435, Santa Cruz, CA, USA), c-Jun (siRNAs; sc-29223, Santa Cruz), and MISSION® siRNA Universal Negative Control

(17) Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in ConfinementAdvanced science (Weinheim, Baden-Wurttemberg, Germany)August 1, 2023Hemmati F, Akinpelu A, Song J, Amiri F, McDaniel A, McMurray C, Afthinos A, Andreadis ST, Aitken AV, Biancardi VC, et al.experiments, cells were transfected with YAP1 siRNA (sc‐38637; Santa Cruz Biotechnology), P53 siRNA (sc‐29435; Santa Cruz Biotechnology), LATS2 siRNA (sc‐37444; Santa Cruz Biotechnology), CHMP2A siRNA (sc‐60369;

(18) 2-(4-Benzyloxy-3-methoxyphenyl)-5-(carbethoxyethylene)-7-methoxy-benzofuran, a Benzofuran Derivative, Suppresses Metastasis Effects in P53-Mutant Hepatocellular Carcinoma CellsBiomedicinesJuly 19, 2023Tseng TH, Shao YC, Lee YJ, Lee HJ.

(19) All-trans Retinoic Acid Inhibits Hepatitis B Virus Replication by Downregulating HBx Levels via Siah-1-Mediated Proteasomal DegradationVirusesJune 27, 2023Han J, Jang KL.(Rockville, MD, USA). Scrambled (SC) short hairpin RNA (shRNA) (Cat No. sc-37007) and p53 shRNA (Cat. sc-29435) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Siah-1 shRNA (Cat No. SHCLND-NM003031)

(20) Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complexNature communicationsJune 23, 2023Sun Y, Baechler SA, Zhang X, Kumar S, Factor VM, Arakawa Y, Chau CH, Okamoto K, Parikh A, Walker B, et al.M-019999-01-0005), DCAF13 siRNA (Dharmacon, Cat# M-017898-01-0005), p53 siRNA (Santa Cruz Biotechnology, sc-29435). Site-directed mutagenesis (SDM) in mammalian expression vectors Myc-CUL4A K705R was generated by

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p53 siRNA (h)

p53 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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p53 siRNA (h) from Santa Cruz Biotechnology, Inc.

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