p300 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemp300 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29431
Quantity10 µM
Gene NameE1A binding protein p300
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene NameE1A binding protein p300
NCBI Gene AliasesKAT3B, MKHK2, RSTS2, p300

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The harmonized activities of HER2–HER3 heterodimer and deacetylated FOXA1 evade hormone response by regulating FOXA1 chromatin bindingNucleic Acids ResearchNovember 11, 2025Shixiong Wang, Gemma Santacana-Font, Darek Kedra, Siv Gilfillan, David Tena-Chaves, Helga Bergholtz, Olav Engebraaten, Ole Christian Lingjaerde, Javier Gutiérrez-Fernández, Jens Henrik Norum, et al.MCF-7 FOXA1 inducible expression stable cells were reverse transfected with siRNA targeting EP300 (sc-29431, Santa Cruz) and siControl with the same method as siFOXA1 at a final concentration of 10 nM. For the

(2) Matrix stiffness induced gallbladder fibroblasts activation and paracrine SEMA7A promotes gallbladder cancer cell epithelial-mesenchymal transition and cancer stem cell-like properties by modulating AKT/p300 signallingBiol DirectAugust 19, 2025Liankang Sun, Huanhuan Wang, Hanqi Li, Ruida Yang, Xuyuan Dong, Danfeng Dong, Yangwei Fan, Enxiao Li, Hao Wang, Yinying Wu, et al.constructs, NM_001429.1-2773s1c1, were sourced from the MISSION shRNA Library (Sigma-Aldrich), P300 shRNA#2 (#sc-29431) was purchased from Santa Cruz Biotechnology. Scrambled siRNA (si-Control: sense 5′-UUCUCCGAACGUGUCACGUTT-3′;

(3) Design, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs)Journal of Medicinal ChemistryAugust 22, 2024Xiaoping Hu, Md Kabir, Yindan Lin, Yan Xiong, Ramon E. Parsons, Wei Gu, Jian Jinhumidified incubator containing 5% CO2 and 95% O2. For siRNA transfection, control and p300 siRNA (sc-29431) were purchased from Santa Cruz Biotechnology. Briefly, NCI-H1299 cells were seeded on 6-well plates

(4) Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53Journal of the American Chemical SocietyJuly 12, 2023Kabir M, Sun N, Hu X, Martin TC, Yi J, Zhong Y, Xiong Y, Kaniskan HÜ, Gu W, Parsons R, et al.humidified incubator containing 5% CO2 and 95% O2. For siRNA transfection, control and p300 siRNA (sc-29431) were purchased from Santa Cruz Biotechnology. Briefly, NCI-H1299 cells were seeded on 6-well plates

(5) Acetylation of Abelson interactor 1 at K416 regulates actin cytoskeleton and smooth muscle contractionFASEB journal : official publication of the Federation of American Societies for Experimental BiologySeptember 1, 2021Wang Y, Liao G, Wang R, Tang DD.with ACh. 2.6 Transfection For p300 knockdown, control siRNA (SC‐37007/Lot# K2320) and p300 siRNA (SC‐29431/Lot # L1918) were purchased from Santa Cruz Biotechnology. HASM cells were transfected with siRNA according

(6) EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathwayOncogeneJanuary 1, 2020Zhang H, Zhu D, Zhang Z, Kaluz S, Yu B, Devi NS, Olson JJ, Van Meir EG.Control-siRNAs were from Santa Cruz (sc-37007) and OriGene (SR30004). EP300-siRNAs were from Santa Cruz (sc-29431) and OriGene (SR320041). CEBPB-siRNAs were from Santa Cruz (sc-29229) and OriGene (SR300760). SMARCA4-siRNAs

(7) Quercetin enhances the antitumor activity of trichostatin A through up-regulation of p300 protein expression in p53 null cancer cellsChemico-biological interactionsJune 1, 2019Chuang CH, Chan ST, Chen CH, Yeh SL.

(8) HSF1 mediated TNF-α production during proteotoxic stress response pioneers proinflammatory signal in human cellsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2019Ali A, Biswas A, Pal M.

(9) Epigenetic regulation of interleukin-8 expression by class I HDAC and CBP in ovarian cancer cellsOncotargetSeptember 19, 2017Gatla HR, Zou Y, Uddin MM, Vancurova I.and reverse, 5’-GCTTGTGTGCTCT-GCTGTCTC-3’. Transfection with siRNA Human HDAC1 (sc-29343), HDAC2 (sc-29345), HDAC3 (sc-35538), p300 (sc-29431), CBP (sc-29244), and non-silencing (sc-37007) small interfering RNAs (siRNAs) were obtained from Santa Cruz Biotechnology

(10) Acetylation of Mastermind-like 1 by p300 Drives the Recruitment of NACK to Initiate Notch-Dependent TranscriptionCancer researchAugust 15, 2017Jin K, Zhou W, Han X, Wang Z, Li B, Jeffries S, Tao W, Robbins DJ, Capobianco AJ.

(11) p300 and C/EBPβ-regulated IKKβ expression are involved in thrombin-induced IL-8/CXCL8 expression in human lung epithelial cellsPharmacological researchJuly 1, 2017Huang ZW, Lien GS, Lin CH, Jiang CP, Chen BC.

(12) Preimplantation factor is an anti-apoptotic effector in human trophoblasts involving p53 signaling pathwayCell death & diseaseDecember 1, 2016Moindjie H, Santos ED, Gouesse RJ, Swierkowski-Blanchard N, Serazin V, Barnea ER, Vialard F, Dieudonné MN.SuperSignal™ West Pico Chemiluminescent Substrate (Thermo Fisher Scientific Inc.). TP53 siRNA knockdown The siRNA for TP53 (p53 siRNA (h): sc29431) was purchased from Santa Cruz Biotechnologies Inc. A fluorescently labeled, non-silencing control siRNA

(13) An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cellsOncology reportsNovember 1, 2016Gu ML, Wang YM, Zhou XX, Yao HP, Zheng S, Xiang Z, Ji F.

(14) Decreased MORF leads to prolonged endoplasmic reticulum stress in periodontitis-associated chronic inflammationCell death and differentiationNovember 1, 2016Xue P, Li B, An Y, Sun J, He X, Hou R, Dong G, Fei D, Jin F, Wang Q, et al.

(15) The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferaseToxicology and applied pharmacologyFebruary 1, 2016Wu TC, Lin YC, Chen HL, Huang PR, Liu SY, Yeh SL.

(16) Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional ComplexPloS oneJanuary 1, 2016Guo Z, Zheng L, Liao X, Geller D.examined by AutoLumat LB 953 luminometer (Berthold). Control siRNA (sc-37007) and siRNA against p300 (sc-29431) were obtained from Santa Cruz Biotechnology, and cells were transfected according to the manufacturer's

(17) Leptin Promotes cPLA₂ Gene Expression through Activation of the MAPK/NF-κB/p300 CascadeInternational journal of molecular sciencesNovember 18, 2015Hsu PS, Wu CS, Chang JF, Lin WN.

(18) Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β ResponsesPLoS pathogensJuly 1, 2015Ansari MA, Dutta S, Veettil MV, Dutta D, Iqbal J, Kumar B, Roy A, Chikoti L, Singh VV, Chandran B.

(19) CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancerCellular signallingJuly 1, 2015Wang G, Cheng Z, Liu F, Zhang H, Li J, Li F.

(20) IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon CancerCancer immunology researchJuly 1, 2015Bardhan K, Paschall AV, Yang D, Chen MR, Simon PS, Bhutia YD, Martin PM, Thangaraju M, Browning DD, Ganapathy V, et al.transiently transfected with scrambled siRNA (Dharmacon, Lafayette, CO), p300-specific siRNA (Cat# sc-29431, Santa Cruz), and STAT1-specific siRNA (Qiagen, cat# SI02662324, SI02662884) respectively, using lipofectamine

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p300 siRNA (h)

p300 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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p300 siRNA (h) from Santa Cruz Biotechnology, Inc.

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