Raptor siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRaptor siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-44069
Gene Nameregulatory associated protein of MTOR, complex 1
Quantity10 µM
Specieshuman
NCBI Full Gene Nameregulatory associated protein of MTOR complex 1
NCBI Gene AliasesKOG1, Mip1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Endothelial Mechanistic Target of Rapamycin Activation with Different Strains of R. rickettsii: Possible Role in Rickettsial PathogenesisMicroorganismsJanuary 30, 2024Abha Sahni, Jessica Alsing, Hema P. Narra, Michelle Montini, Yasim Zafar, Sanjeev K. Sahniwere used as a mock control. In some experiments, mTORC1-specific Raptor siRNA (25 or 50 nM, catalog #sc-44069), mTORC2-specific Rictor siRNA (25 or 50 nM, catalog #sc-61478), or control siRNA (50 nM, catalog #sc-44230)

(2) mTOR inhibition suppresses salinomycin-induced ferroptosis in breast cancer stem cells by ironing out mitochondrial dysfunctionsCell Death & DiseaseNovember 15, 2023Emma Cosialls, Emeline Pacreau, Clémence Duruel, Sara Ceccacci, Rima Elhage, Christophe Desterke, Kevin Roger, Chiara Guerrera, Romane Ducloux, Sylvie Souquere, et al.sub-confluence with 10 nM of si-CTRL (D001810-10-20, ThermoFisherScientific, ON-TARGET™plus control), si-RAPTOR (sc-44069, Santa Cruz), si-SIN1 (sc-60984, Santa Cruz) were mixed with 3 μL/well of Lipofectamine RNAiMAX (13778-150,

(3) PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysisNature communicationsApril 29, 2023Bertschi NL, Steck O, Luther F, Bazzini C, von Meyenn L, Schärli S, Vallone A, Felser A, Keller I, Friedli O, et al.Silencer™ Select Negative Control No. 1 siRNA (Thermo Fisher Scientific) or RPTOR siRNA (Santa Cruz #sc-44069). After 12 h, transfected cells were analyzed by RT-qPCR and stimulated with αCD3/CD2/CD28 for 24 h.

(4) Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolismMolecular metabolismApril 1, 2023Ferguson D, Eichler SJ, Yiew NKH, Colca JR, Cho K, Patti GJ, Shew TM, Lutkewitte AJ, Mukherjee S, McCommis KS, et al.

(5) mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncouplingCommunications biologyJuly 22, 2022Wang Y, Li Q, Zhang Z, Peng K, Zhang DM, Yang Q, Passerini AG, Simon SI, Sun C.Cell transfection Negative control siRNA (sc-37007), siRNA targeting KLF2 (sc-35818), RPTOR (encoding Raptor) (sc-44069), RICTOR (sc-61478), MTOR (sc-35409), RPS6KB1 (encoding p70S6K) (sc-36165) were purchased from Santa Cruz Biotechnology

(6) eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damageOncogeneApril 1, 2022Ma S, Dong Z, Huang Y, Liu JY, Zhang JT.

(7) Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supplyProceedings of the National Academy of Sciences of the United States of AmericaJanuary 19, 2021Shao X, Cao G, Chen D, Liu J, Yu B, Liu M, Li YX, Cao B, Sadovsky Y, Wang YL.

(8) Different Role of Raptor and Rictor in Regulating Rasfonin-Induced Autophagy and Apoptosis in Renal Carcinoma CellsChemistry & biodiversityDecember 1, 2020Hou B, Liu S, Li E, Jiang X.

(9) Differential roles and activation of mammalian target of rapamycin complexes 1 and 2 during cell migration in prostate cancer cellsThe ProstateApril 1, 2020Venugopal SV, Caggia S, Gambrell-Sanders D, Khan SA.

(10) Targeting Mechanistic Target of Rapamycin Complex 1 Restricts Proinflammatory T Cell Differentiation and Ameliorates Takayasu ArteritisArthritis & rheumatology (Hoboken, N.J.)February 1, 2020Zhang J, Zhao L, Wang J, Cheng Z, Sun M, Zhao J, Liu B, Liu X, Wen Z, Li Z.

(11) The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling PathwaysCell reportsMarch 12, 2019Xie CM, Tan M, Lin XT, Wu D, Jiang Y, Tan Y, Li H, Ma Y, Xiong X, Sun Y.ERK1: 5′-CATGAAGGCCCGAAACTAC-3′; ERK2: 5′-GCGCTTCAGACATGAGAAC-3′ (Xie et al., 2015). Raptor siRNA (SC-44069) was obtained from Santa Cruz. Briefly, cells were transfected with various siRNAs or shRNAs in MEM

(12) Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNF-α-induced VCAM-1 expression and monocytic cell adhesionAmerican journal of physiology. Heart and circulatory physiologyFebruary 1, 2019Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG, Simon SI, Sun C.

(13) Nox4 is a Target for Tuberin Deficiency SyndromeScientific reportsFebruary 28, 2018Shi Q, Viswanadhapalli S, Friedrichs WE, Velagapudi C, Szyndralewiez C, Bansal S, Bhat MA, Choudhury GG, Abboud HE.and infection Control siRNA (sc-37007) and pools of siRNAs against tuberin (sc-36762) and Raptor (sc-44069), were purchased from Santa Cruz Biotechnology (Santa Cruz, CA); siRNAs against S6K1 (#SR304164) were

(14) microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1OncotargetJanuary 5, 2018Liu G, Chen FL, Ji F, Fei HD, Xie Y, Wang SG.

(15) Mammalian Target of Rapamycin Complex 1 Activation Disrupts the Low-Density Lipoprotein Receptor Pathway: A Novel Mechanism for Extracellular Matrix Accumulation in Human Peritoneal Mesothelial CellsAmerican journal of nephrologyJanuary 1, 2018Liu J, Zhu W, Jiang CM, Feng Y, Xia YY, Zhang QY, Xu PF, Zhang M.

(16) mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human MonocytesFrontiers in immunologyJanuary 1, 2018Sohrabi Y, Lagache SMM, Schnack L, Godfrey R, Kahles F, Bruemmer D, Waltenberger J, Findeisen HM.were transfected with final concentrations of 60 nM small interfering RNA for Raptor (Santa Cruz, #sc-44069) and Rictor (Santa Cruz, #sc-61478) for 24 h using Viromer technology according to the manufacturer's

(17) The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathwayScience translational medicineJuly 19, 2017Wen Z, Shen Y, Berry G, Shahram F, Li Y, Watanabe R, Liao YJ, Goronzy JJ, Weyand CM.

(18) Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acidThe Journal of biological chemistryApril 14, 2017Menon D, Salloum D, Bernfeld E, Gorodetsky E, Akselrod A, Frias MA, Sudderth J, Chen PH, DeBerardinis R, Foster DA.

(19) A novel mechanism of mTORC1-mediated serine/glycine metabolism in osteosarcoma developmentCellular signallingJanuary 1, 2017Wang DW, Wu L, Cao Y, Yang L, Liu W, E XQ, Ji G, Bi ZG.

(20) Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertensionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJuly 1, 2016Aghamohammadzadeh R, Zhang YY, Stephens TE, Arons E, Zaman P, Polach KJ, Matar M, Yung LM, Yu PB, Bowman FP, et al.

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Raptor siRNA (h)

Raptor siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Raptor siRNA (h) from Santa Cruz Biotechnology, Inc.

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