SH-PTP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSH-PTP1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29478
Gene Nameprotein tyrosine phosphatase, non-receptor type 6
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein tyrosine phosphatase non-receptor type 6
NCBI Gene AliasesHCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) ADAM17, induced by Augmenter of Liver Regeneration via G protein-coupled receptor activation, transactivates epidermal growth factor-receptor and reduces classical IL-6 signalingCell Communication and SignalingMarch 7, 2026Christoph Voigt, Sophie Menzel, Rania Dayoub, Marion Kubitza, Florian Schmutzler, Christa Buechler, Elke Eggenhofer, Michael Melter, Thomas S. WeissGNAQ siRNA (s5887; Thermo Fisher Scientific, Darmstadt, Germany), ADAM17 siRNA (sc-36604), SHP1 siRNA (sc-29478) or a scrambled control siRNA (sc-37007; all from Santa Cruz Biotechnology, Heidelberg, Germany) for

(2) Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cellsBMC cancerFebruary 6, 2018Kim SH, Yoo HS, Joo MK, Kim T, Park JJ, Lee BJ, Chun HJ, Lee SW, Bak YT.

(3) Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducerCell & bioscienceJanuary 1, 2018Koh JS, Joo MK, Park JJ, Yoo HS, Choi BI, Lee BJ, Chun HJ, Lee SW.images were captured by using a high-resolution digital camera (Carl Zeiss). Transfection SHP-1 (sc-29478) and control (sc-37007) siRNA were purchased from Santa Cruz Biotechnology. For transient small interfering

(4) The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3OncotargetApril 11, 2017Sakurai T, Higashitsuji H, Kashida H, Watanabe T, Komeda Y, Nagai T, Hagiwara S, Kitano M, Nishida N, Abe T, et al.

(5) Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse modelMolecular carcinogenesisOctober 1, 2015Shanmugam MK, Rajendran P, Li F, Kim C, Sikka S, Siveen KS, Kumar AP, Ahn KS, Sethi G.

(6) Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatasesCancer lettersApril 1, 2014Lee JH, Chiang SY, Nam D, Chung WS, Lee J, Na YS, Sethi G, Ahn KS.

(7) Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3British journal of pharmacologyOctober 1, 2013Subramaniam A, Shanmugam MK, Ong TH, Li F, Perumal E, Chen L, Vali S, Abbasi T, Kapoor S, Ahn KS, et al.purchased from Cell Signalling Technology (Beverly, MA, USA). The small interfering RNA (siRNA) for SHP-1 (sc29478) and scrambled control (sc-37007) was obtained from Santa Cruz Biotechnology. SHP-1 siRNA is a pool

(8) Thrombospondin-1 modulates VEGF signaling via CD36 by recruiting SHP-1 to VEGFR2 complex in microvascular endothelial cellsBloodSeptember 5, 2013Ling-Yun Chu, Devi Prasadh Ramakrishnan, Roy L. Silverstein6-well plates. Cells were incubated with 60nmol/L siRNAs (Santa Cruz) targeting CD36 (sc-29995), SHP-1 (sc-29478), SHP-2 (sc-36488), Fyn (sc-29321), or Syk (sc-29501), or control “scrambled” siRNA (sc-37007) and 6µL

(9) Antagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathwayBloodDecember 6, 2012Kim SH, Cho YR, Kim HJ, Oh JS, Ahn EK, Ko HJ, Hwang BJ, Lee SJ, Cho Y, Kim YK, et al.gelatin-coated 100-mm dishes were transfected with siRNA (integrin ␣3 siRNA (sc-35684), 50nM; Shp-1 siRNA (sc29478), 50nM; Shp-2 siRNA (sc-36488), 50nM; control siRNA (sc-37007), 50nM) using Lipofectamine RNAiMAX (Invitrogen)

(10) Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1Journal of cellular physiologyMay 1, 2012Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.

(11) Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu micePloS oneJanuary 1, 2012Liu SH, Wang KB, Lan KH, Lee WJ, Pan HC, Wu SM, Peng YC, Chen YC, Shen CC, Cheng HC, et al.calpain II, and scrambled control were used and purchased from Santa Cruz Biotechnology (SHP-1 siRNA, sc-29478; Calpain II siRNA, sc-41459; Control siRNA, sc-37007). Immunohistochemistry The expressions of SHP-1

(12) Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cellsLeukemiaNovember 1, 2011Tibaldi E, Brunati AM, Zonta F, Frezzato F, Gattazzo C, Zambello R, Gringeri E, Semenzato G, Pagano MA, Trentin L.interfering RNA (siRNA) and negative control siRNA were from Santa Cruz Biotechnology (catalog number sc-29478). Anti-phospho-SykTyr525/526 antibody was from (Cell Signaling Technology, Danvers, MA, USA). Goat F(ab0

(13) γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agentBritish journal of pharmacologyMay 1, 2011Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.procaspase-3 and PARP were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). The siRNA for SHP-1 (sc-29478) and scrambled control (sc-37007) was obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

(14) The tyrosine phosphatase, SHP-1, is involved in bronchial mucin production during oxidative stressBiochemical and biophysical research communicationsFebruary 26, 2010Jang MK, Kim SH, Lee KY, Kim TB, Moon KA, Park CS, Bae YJ, Zhu Z, Moon HB, Cho YS.

(15) Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activityBloodNovember 26, 2009Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV.

(16) Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*Journal of molecular signalingMarch 31, 2008Bhattacharya R, Kwon J, Wang E, Mukherjee P, Mukhopadhyay D.reduced serum medium and transfected with 50 nM SHP-1 siRNA obtained from Santa Cruz Biotechnology (sc29478) using oligofectamine (Invitrogen). This siRNA is a pool of 3 sequences. Sense Strand (A):CUGGUGGAGCAUUUCAAGATT,

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SH-PTP1 siRNA (h)

SH-PTP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SH-PTP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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