SREBP-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSREBP-2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36559
Gene Namesterol regulatory element binding transcription factor 2
Quantity10 µM
Specieshuman
NCBI Full Gene Namesterol regulatory element binding transcription factor 2
NCBI Gene AliasesSREBP-2, SREBP2, bHLHd2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Toxoplasma gondii sustains survival by regulating cholesterol biosynthesis and uptake via SREBP2 activationJournal of lipid researchDecember 1, 2024Fan YM, Zhang QQ, Pan M, Hou ZF, Fu L, Xu X, Huang SY.line HeLa cells were maintained in DMEM with 10% FBS in 24-well plates. The shRNA targeting human SREBP-2 (sc-36559) and shRNA control (sc-37007) were purchased from Santa Cruz Biotechnology. The cells were transfected

(2) Lipophagy-mediated cholesterol synthesis inhibition is required for the survival of hepatocellular carcinoma under glutamine deprivationRedox biologyJuly 1, 2023Kong Y, Wu M, Wan X, Sun M, Zhang Y, Wu Z, Li C, Liang X, Gao L, Ma C, et al.previous paper [13]. Scrambled siRNAs were synthesized in Sangon Biotech. siRNAs that target on SREBF2 (sc-36559), Insig 1 (sc-44432), NPC1 (sc-41588), ATG7 (sc-41447), TSC2 (sc-36762) and NPRL2 (sc-62699) are the

(3) LXRα Regulates oxLDL-Induced Trained Immunity in MacrophagesInternational journal of molecular sciencesMay 31, 2022Findeisen HM, Voges VC, Braun LC, Sonnenberg J, Schwarz D, Körner H, Reinecke H, Sohrabi Y.#sc-45316), SREBP1 (Santa Cruz, Dallas, TX, USA, #sc-36557), SREBP2 (Santa Cruz, Dallas, TX, USA, #sc-36559) or Scramble RNA (Santa Cruz, Dallas, TX, USA, #sc-37007) using the Lipofectamine RNAiMAX Transfection Reagent

(4) Characterization of the promoter region of the bovine IRX3 gene: roles of SREBF2 and PPARGPhysiological genomicsMarch 1, 2020Wei D, Raza SHA, Zhang J, Wang X, Khan R, Ma Y, Zhang G, Luoreng Z, Zan L.

(5) RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtypeNature communicationsOctober 11, 2019Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, et al.RORC were published previously27. siRNA against SREBP2 was purchased from Santa Cruz Biotechnology (sc-36559). Transfections were performed with OptiMEM (Invitrogen) and Dharmafectin#1 (Dharmacon) following the

(6) Bisphenol A induces cholesterol biosynthesis in HepG2 cells via SREBP-2/HMGCR signaling pathwayThe Journal of toxicological sciencesJanuary 1, 2019Li Q, Zhang H, Zou J, Feng X, Feng D.

(7) Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated LipogenesisClinical cancer research : an official journal of the American Association for Cancer ResearchNovember 1, 2016Geng F, Cheng X, Wu X, Yoo JY, Cheng C, Guo JY, Mo X, Ru P, Hurwitz B, Kim SH, et al.

(8) SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expression in Vivo and in Vitro through a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoterThe Journal of biological chemistryMarch 4, 2016Singh AB, Kan CF, Dong B, Liu J.

(9) Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding ProteinsPloS oneJanuary 1, 2015Ochiai A, Miyata S, Shimizu M, Inoue J, Sato R.and 5′-CATGTCTTCGAAAGTGCAATCC–3′, respectively. siRNA experiments SREBP–1 (sc–36557) and SREBP–2 (sc–36559) siRNAs were obtained from Santa Cruz, and control siRNA (pGL2 luciferase) was obtained from Bonac.

(10) Up-regulation of hepatic low-density lipoprotein receptor-related protein 1: a possible novel mechanism of antiatherogenic activity of hydroxymethylglutaryl-coenzyme A reductase inhibitor Atorvastatin and hepatic LRP1 expressionMetabolism: clinical and experimentalJuly 1, 2011Moon JH, Kang SB, Park JS, Lee BW, Kang ES, Ahn CW, Lee HC, Cha BS.

(11) Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagyCell metabolismApril 6, 2011Seo YK, Jeon TI, Chong HK, Biesinger J, Xie X, Osborne TF.serum (FCS) and antibiotics in an atmosphere of 5% CO2 at 37°C. The siRNA targeting human SREBP-2 (sc-36559) and siRNA control (sc-37007) were purchased from Santa Cruz Biotechnology. The cells were transfected

(12) Digoxin and ouabain increase the synthesis of cholesterol in human liver cellsCellular and molecular life sciences : CMLSMay 1, 2009Campia I, Gazzano E, Pescarmona G, Ghigo D, Bosia A, Riganti C.

(13) SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cellsNature cell biologyFebruary 1, 2009Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, et al.vector. SREBP2 knockdown in cultured human VSMCs Control siRNA (siCNTRL, Santa Cruz, sc-37007) or SREBP2 siRNA (sc-36559) were transfected into cultured VSMCs using Metafectene (Biontex) according to the manufacturer’s instruction. Western blotting

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SREBP-2 siRNA (h)

SREBP-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SREBP-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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