IL-6 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIL-6 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-39627
Quantity10 µM
Specieshuman
NCBI Full Gene Nameinterleukin 6
NCBI Gene AliasesCDF, HSF, BSF-2, IL-6, IFNB2, HGF, BSF2, IFN-beta-2
TypesiRNA/dsRNA
Gene Nameinterleukin 6 (interferon, beta 2)

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) CORM-2 prevents human gingival fibroblasts from lipoteichoic acid-induced VCAM-1 and ICAM-1 expression by inhibiting TLR2/MyD88/TRAF6/PI3K/Akt/ROS/NF-κB signaling pathwayBiochemical pharmacologyJuly 1, 2022Cheng CY, Chen YH, Thuy Tien Vo T, Chui Hong Y, Wang CS, Canh Vo Q, Chou HC, Huang TW, Lee IT.

(2) Carbon Monoxide-Releasing Molecule-2 Ameliorates Particulate Matter-Induced Aorta Inflammation via Toll-Like Receptor/NADPH Oxidase/ROS/NF-κB/IL-6 InhibitionOxidative medicine and cellular longevityJanuary 1, 2021Vo TTT, Hsu CY, Wee Y, Chen YL, Cheng HC, Wu CZ, Lin WN, Lee IT.

(3) Tocilizumab inhibits IL-8 and the proangiogenic potential of triple negative breast cancer cellsMolecular carcinogenesisJanuary 1, 2021Alraouji NN, Aboussekhra A.

(4) Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancerMolecular carcinogenesisSeptember 1, 2020Alraouji NN, Al-Mohanna FH, Ghebeh H, Arafah M, Almeer R, Al-Tweigeri T, Aboussekhra A.

(5) ID1 confers cancer cell chemoresistance through STAT3/ATF6-mediated induction of autophagyCell death & diseaseFebruary 20, 2020Meng J, Liu K, Shao Y, Feng X, Ji Z, Chang B, Wang Y, Xu L, Yang G.knocking down of IL-6 using IL-6 siRNA in ID1 overexpression cell lines. IL-6 small interfering RNA (sc-39627) and control siRNA (sc-37007) were purchased from Santa Cruz Technology (California, USA). Transfection

(6) Interleukin 6-triggered ataxia-telangiectasia mutated kinase activation facilitates epithelial-to-mesenchymal transition in lung cancer by upregulating vimentin expressionExperimental cell researchAugust 15, 2019Jiang YN, Ni XY, Yan HQ, Shi L, Lu NN, Wang YN, Li Q, Gao FG.

(7) Matrine increases the inhibitory effects of afatinib on H1975 cells via the IL‑6/JAK1/STAT3 signaling pathwayMolecular medicine reportsSeptember 1, 2017Chen SF, Zhang ZY, Zhang JL.Massachusetts, MA, USA). Small interfering RNA (siRNA) H1975 cells were transfected with IL-6 siRNA (sc-39627; Santa Cruz Biotechnology, Inc., Paso Robles, CA, USA) or negative control siRNA (sc-37007; Santa Cruz Biotechnology, Inc

(8) Inflammatory landscape of human brain tumors reveals an NFκB dependent cytokine pathway associated with mesenchymal glioblastomaCancer lettersApril 1, 2017Zanotto-Filho A, Gonçalves RM, Klafke K, de Souza PO, Dillenburg FC, Carro L, Gelain DP, Moreira JC.

(9) IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathwayOncotargetMarch 28, 2017Wu X, Tao P, Zhou Q, Li J, Yu Z, Wang X, Li J, Li C, Yan M, Zhu Z, et al.

(10) Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cellsInternational journal of oncologyMarch 1, 2015Suh YA, Jo SY, Lee HY, Lee C.seeded in 100-mm culture dish and grown overnight and then transfected with 50 nM siRNA against IL-6 (sc-39627; Santa Cruz Biotechnology, Dallas, TX, USA), or control siRNA (sc-37007; Santa Cruz Biotechnology).

(11) Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injuryThe Journal of biological chemistryOctober 3, 2014Francis H, McDaniel K, Han Y, Liu X, Kennedy L, Yang F, McCarra J, Zhou T, Glaser S, Venter J, et al.

(12) Feedback activation of STAT3 mediates trastuzumab resistance via upregulation of MUC1 and MUC4 expressionOncotargetSeptember 30, 2014Li G, Zhao L, Li W, Fan K, Qian W, Hou S, Wang H, Dai J, Wei H, Guo Y.

(13) Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activationCancer scienceSeptember 1, 2014Yan HQ, Huang XB, Ke SZ, Jiang YN, Zhang YH, Wang YN, Li J, Gao FG.

(14) STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypesScience signalingJanuary 28, 2014Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, et al.Thermo Scientific Dharmacon, RelA siRNA (6261) was from Cell Signaling Technology, and IL-6 siRNA (sc-39627) was from Santa Cruz Biotechnology. EMSA The LightShift EMSA Kit (Pierce) was used according to the

(15) Syk/JNK/AP-1 signaling pathway mediates interleukin-6-promoted cell migration in oral squamous cell carcinomaInternational journal of molecular sciencesJanuary 6, 2014Chuang JY, Huang YL, Yen WL, Chiang IP, Tsai MH, Tang CH.

(16) IL-6 promotes ICAM-1 expression and cell motility in human osteosarcomaCancer lettersJanuary 1, 2013Lin YM, Chang ZL, Liao YY, Chou MC, Tang CH.

(17) STAT3 is necessary for proliferation and survival in colon cancer-initiating cellsCancer researchDecember 1, 2011Lin L, Liu A, Peng Z, Lin HJ, Li PK, Li C, Lin J.

(18) IL-6 increases MMP-13 expression and motility in human chondrosarcoma cellsThe Journal of biological chemistryApril 1, 2011Tang CH, Chen CF, Chen WM, Fong YC.

(19) Radiation-induced interleukin-6 expression through MAPK/p38/NF-kappaB signaling pathway and the resultant antiapoptotic effect on endothelial cells through Mcl-1 expression with sIL6-RalphaInternational journal of radiation oncology, biology, physicsDecember 1, 2009Chou CH, Chen SU, Cheng JC.

(20) ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosisRNA biologyJanuary 1, 0001Ben-Shoshan SO, Kagan P, Sultan M, Barabash Z, Dor C, Jacob-Hirsch J, Harmelin A, Pappo O, Marcu-Malina V, Ben-Ari Z, et al.

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IL-6 siRNA (h)

IL-6 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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IL-6 siRNA (h) from Santa Cruz Biotechnology, Inc.

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