FAK siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemFAK siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29310
Gene NamePTK2 protein tyrosine kinase 2
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein tyrosine kinase 2
NCBI Gene AliasesFADK, FADK 1, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Myocardial Cytoskeletal Adaptations in Advanced Kidney DiseaseJournal of the American Heart AssociationMarch 1, 2022Halim A, Narayanan G, Hato T, Ho L, Wan D, Siedlecki AM, Rhee EP, Allegretti AS, Nigwekar SU, Zehnder D, et al.starved for 24 hours prior to transfection with either focal adhesion kinase (FAK) siRNA (Cat. No. sc‐29310; Santa Cruz Biotechnology, Dallas, TX) or siRNA‐B (Cat. No. sc‐44230; Santa Cruz Biotechnology, Dallas,

(2) G9a Promotes Invasion and Metastasis of Non-Small Cell Lung Cancer through Enhancing Focal Adhesion Kinase Activation via NF-κB Signaling PathwayMolecular cancer research : MCRMarch 1, 2021Sun T, Zhang K, Pangeni RP, Wu J, Li W, Du Y, Guo Y, Chaurasiya S, Arvanitis L, Raz DJ.expression by using RNAi maxi reagent (Invitrogen, USA) as describe previously (20). A FAK siRNA (Cat#: sc-29310) was purchased from Santa Cruz Company. Cells were transfected with G9a-pcDNA3.1 plasmid and pcDNA3.1

(3) Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocinPLoS pathogensOctober 1, 2020Kamarajan P, Ateia I, Shin JM, Fenno JC, Le C, Zhan L, Chang A, Darveau R, Kapila YL.

(4) Engineering blood outgrowth endothelial cells to optimize endothelial nitric oxide synthase and extracellular matrix production for coating of blood contacting surfacesActa biomaterialiaJune 1, 2020Yuan Y, Khan S, Stewart DJ, Courtman DW.

(5) β1 integrin-mediated signaling regulates MT1-MMP phosphorylation to promote tumor cell invasionJournal of cell scienceMay 14, 2020Grafinger OR, Gorshtein G, Stirling T, Brasher MI, Coppolino MG.doi:10.1242/jcs.239152 Technologies. Src, FAK and control siRNA were purchased from Santa Cruz Biotechnology (sc-29228, sc-29310, and sc-37007, respectively). Cell culture and transfection MDA-MB-231 and HT-1080 cells were obtained

(6) The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistanceOncogeneFebruary 1, 2020Asare-Werehene M, Nakka K, Reunov A, Chiu CT, Lee WT, Abedini MR, Wang PW, Shieh DB, Dilworth FJ, Carmona E, et al.

(7) Fluid flow-induced activation of subcellular AMPK and its interaction with FAK and SrcArchives of biochemistry and biophysicsJanuary 15, 2020Guo Y, Steele HE, Li BY, Na S.

(8) CRISPR/Cas9 engineering of ERK5 identifies its FAK/PYK2 dependent role in adhesion-mediated cell survivalBiochemical and biophysical research communicationsMay 21, 2019Ali M, Mutahir Z, Riaz A.

(9) Simulated microgravity inhibits the viability and migration of glioma via FAK/RhoA/Rock and FAK/Nek2 signalingIn vitro cellular & developmental biology. AnimalApril 1, 2019Deng B, Liu R, Tian X, Han Z, Chen J.

(10) The diacylglycerol kinase α (DGKα)/Akt/NF-κB feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent mannerOncogeneApril 1, 2019Chen J, Zhang W, Wang Y, Zhao D, Wu M, Fan J, Li J, Gong Y, Dan N, Yang D, et al.

(11) FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxisFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2018Lachowski D, Cortes E, Robinson B, Rice A, Rombouts K, Del Río Hernández AE.

(12) Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1Molecular cancer research : MCRJune 1, 2017Ikezono Y, Koga H, Akiba J, Abe M, Yoshida T, Wada F, Nakamura T, Iwamoto H, Masuda A, Sakaue T, et al.

(13) Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate CellsScientific reportsMay 31, 2017Lachowski D, Cortes E, Pink D, Chronopoulos A, Karim SA, P Morton J, Del Río Hernández AE.microscope using 20x objective. After cell seeding (control, with 50 µM blebbistatin and with siRNA FAK sc-29310 Santa Cruz Biotechnology transfected with Neon Transfection System, ThermoFisher) onto double rigidity

(14) MicroRNA-19b Mediates Lung Epithelial-Mesenchymal Transition via Phosphatidylinositol-3,4,5-Trisphosphate 3-Phosphatase in Response to Mechanical StretchAmerican journal of respiratory cell and molecular biologyJanuary 1, 2017Mao P, Li J, Huang Y, Wu S, Pang X, He W, Liu X, Slutsky AS, Zhang H, Li Y.

(15) Transglutaminase Interaction with α6/β4-Integrin Stimulates YAP1-Dependent ΔNp63α Stabilization and Leads to Enhanced Cancer Stem Cell Survival and Tumor FormationCancer researchDecember 15, 2016Fisher ML, Kerr C, Adhikary G, Grun D, Xu W, Keillor JW, Eckert RL.(A21424) and Alexaflour 488 (A11034) were from Invitrogen. TG2- (sc-37514), p63- (sc-36161), FAK- (sc-29310), integrin α6- (sc-43129), integrin β4- (sc-35678) and control-siRNA (sc-37007) were from Santa Cruz

(16) Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells from Apoptosis, Detachment, and DifferentiationStem cell reportsAugust 9, 2016Vitillo L, Baxter M, Iskender B, Whiting P, Kimber SJ.Amaxa Nucleofector following the manufacturer's instructions (Lonza), with target-specific FAK siRNA (sc-29310, Santa Cruz Biotechnology) at a final concentration of 200 nM, β-2-microglobulin siRNA control (Life

(17) Cucurbitacin B inhibits breast cancer metastasis and angiogenesis through VEGF-mediated suppression of FAK/MMP-9 signaling axisThe international journal of biochemistry & cell biologyAugust 1, 2016Sinha S, Khan S, Shukla S, Lakra AD, Kumar S, Das G, Maurya R, Meeran SM.

(18) Platelet-activating factor receptor-mediated PI3K/AKT activation contributes to the malignant development of esophageal squamous cell carcinomaOncogeneOctober 1, 2015Chen J, Lan T, Zhang W, Dong L, Kang N, Zhang S, Fu M, Liu B, Liu K, Zhang C, et al.

(19) Focal adhesion kinase activation is required for TNF-α-induced production of matrix metalloproteinase-2 and proinflammatory cytokines in cultured human periodontal ligament fibroblastsEuropean journal of oral sciencesAugust 1, 2015Zhang P, Li YJ, Guo LY, Wang GF, Lu K, Yue EL.

(20) PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasionProceedings of the National Academy of Sciences of the United States of AmericaJuly 14, 2015Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, et al.

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FAK siRNA (h)

FAK siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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FAK siRNA (h) from Santa Cruz Biotechnology, Inc.

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