DR5 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDR5 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-40237
Gene Nametumor necrosis factor receptor superfamily, member 10b
Quantity10 µM
Specieshuman
NCBI Full Gene NameTNF receptor superfamily member 10b
NCBI Gene AliasesCD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Chaetocin enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑mediated apoptosis by enhancing DR5 stabilization and reactive oxygen species generation in human glioblastoma cellsInternational journal of oncologyJune 1, 2025Jung HJ, Kim JK, Suh SI, Baek WK.RNA interference DR5-targeting and scrambled siRNAs were purchased from Santa Cruz Biotechnology Co., Ltd. (cat. nos. sc-40237 and sc-37007, respectively; sequences not available). U87MG and T98G cells were seeded in 6-well plates

(2) Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †Cancer biology & therapyDecember 31, 2023Vunnam N, Young MC, Liao EE, Lo CH, Huber E, Been M, Thomas DD, Sachs JN.siRNA For DR5 knockdown experiments, DR5 siRNA Gene Silencer was purchased from Santa Cruz Biotechnology (sc-40237, Santa Cruz Biotechnology). Cells were transfected with DR5 siRNA (25 nM) using lipofectamine 3000 (Invitrogen)

(3) Death receptor 5 promotes tumor progression in gastric cancerFEBS Open BioNovember 14, 2023Junbing Chen, Lin Li, Longtao Huangfu, Hong Du, Xin Ji, Xiaofang Xing, Jiafu Jiusing imagej (NIH). RNA interference The si‐Control (sc‐37007) and siRNA of DR4 (sc‐35218) or DR5 (sc‐40237) were purchased from Santa Cruz. Multiple siRNAs were pooled to interfere with the cancer cells according

(4) NT157 inhibits cell proliferation and sensitizes glioma cells to TRAIL-induced apoptosis by up-regulating DR5 expressionBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieSeptember 1, 2022Hou YJ, Li D, Wang W, Mao L, Fu X, Sun B, Fan C.

(5) AF8c, a Multi-Kinase Inhibitor Induces Apoptosis by Activating DR5/Nrf2 via ROS in Colorectal Cancer CellsCancersJune 21, 2022Jeong S, Farag AK, Yun HK, Jeong YA, Kim DY, Jo MJ, Park SH, Kim BR, Kim JL, Kim BG, et al.

(6) Enhanced extrinsic apoptosis of therapy-induced senescent cancer cells using a death receptor 5 (DR5) selective agonistCancer lettersJanuary 28, 2022Soto-Gamez A, Wang Y, Zhou X, Seras L, Quax W, Demaria M.

(7) P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9Neoplasia (New York, N.Y.)March 1, 2021Tian X, Ahsan N, Lulla A, Lev A, Abbosh P, Dicker DT, Zhang S, El-Deiry WS.

(8) CUDC-907 enhances TRAIL-induced apoptosis through upregulation of DR5 in breast cancer cellsJournal of cell communication and signalingDecember 1, 2020Li ZJ, Hou YJ, Hao GP, Pan XX, Fei HR, Wang FZ.

(9) TRAIL receptor agonists convert the response of breast cancer cells to ONC201 from anti-proliferative to apoptoticOncotargetOctober 20, 2020Ralff MD, Jhaveri A, Ray JE, Zhou L, Lev A, Campbell KS, Dicker DT, Ross EA, El-Deiry WS.

(10) Selinexor Sensitizes TRAIL-R2-Positive TNBC Cells to the Activity of TRAIL-R2xCD3 Bispecific AntibodyCellsOctober 2, 2020Martini S, Figini M, Croce A, Frigerio B, Pennati M, Gianni AM, De Marco C, Daidone MG, Argueta C, Landesman Y, et al.

(11) Ampelopsin Induces DR5-Mediated Apoptotic Cell Death in EBV-Infected Cells through the p38 PathwayNutrition and cancerJanuary 1, 2020Yun SM, Kim YS, Kim KH, Hur DY.

(12) The miR-372-ZBTB7A Oncogenic Axis Suppresses TRAIL-R2 Associated Drug Sensitivity in Oral CarcinomaFrontiers in oncologyJanuary 1, 2020Yeh LY, Yang CC, Wu HL, Kao SY, Liu CJ, Chen YF, Lin SC, Chang KW.

(13) Caudatin potentiates the anti-tumor effects of TRAIL against human breast cancer by upregulating DR5Phytomedicine : international journal of phytotherapy and phytopharmacologySeptember 1, 2019Fei HR, Yuan C, Wang GL, Zhao Y, Li ZJ, Du X, Wang FZ.

(14) Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal CancerCancersMay 9, 2019Kim JL, Kim BR, Kim DY, Jeong YA, Jeong S, Na YJ, Park SH, Yun HK, Jo MJ, Kim BG, et al.

(15) Reversine induces cell cycle arrest and apoptosis via upregulation of the Fas and DR5 signaling pathways in human colorectal cancer cellsInternational journal of oncologyMay 1, 2019Park YL, Ha SY, Park SY, Choi JH, Jung MW, Myung DS, Kim HS, Joo YE.

(16) RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancerOncogeneMay 1, 2019Kim BR, Park SH, Jeong YA, Na YJ, Kim JL, Jo MJ, Jeong S, Yun HK, Oh SC, Lee DH.

(17) Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of sclerodermaNature communicationsMarch 8, 2019Park JS, Oh Y, Park YJ, Park O, Yang H, Slania S, Hummers LK, Shah AA, An HT, Jang J, et al.

(18) Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5Journal of cellular biochemistryJanuary 1, 2019Lee YS, Lee DH, Jeong SY, Park SH, Oh SC, Park YS, Yu J, Choudry HA, Bartlett DL, Lee YJ.synergy; 0.1–0.3, strong synergy; <0.1, very strong synergy. Small Interfering RNA (siRNA) DR5 siRNA (sc-40237) and negative control siRNA (sc-37007) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA).

(19) Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma CellsInternational journal of molecular sciencesOctober 22, 2018Shahriyar SA, Woo SM, Seo SU, Min KJ, Kwon TK.

(20) Gallic Acid Induces Apoptosis in Human Gastric Adenocarcinoma CellsAnticancer researchApril 1, 2018Tsai CL, Chiu YM, Ho TY, Hsieh CT, Shieh DC, Lee YJ, Tsay GJ, Wu YY.

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DR5 siRNA (h)

DR5 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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DR5 siRNA (h) from Santa Cruz Biotechnology, Inc.

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