LKB1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemLKB1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35816
Gene Nameserine/threonine kinase 11
Quantity10 µM
Specieshuman
NCBI Full Gene Nameserine/threonine kinase 11
NCBI Gene AliasesLKB1, PJS, hLKB1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Downregulation of Tumor Suppressor Gene LKB1 During Severe Primary Graft Dysfunction After Human Lung Transplantation: Implication for the Development of Chronic Lung Allograft DysfunctionTransplantationMarch 1, 2025Mohammad Rahman, Davide Scozzi, Natsuki Eguchi, Rachel Klein, Narendra V. Sankpal, Angara Sureshbabu, Timothy Fleming, Ramsey Hachem, Michael Smith, Ross Bremner, et al.cells/cm2 unless otherwise mentioned. For small interfering RNA delivery (LKB1; Santa Cruz Biotechnology [sc-35816]), 2 × 105 cells were grown in a 6-well plate for 24 h in an antibiotic-free medium, and 80 Pico moles

(2) The LKB1–AMPK Signaling Axis Modulates Ferroptosis in Fibroblast-Like Synoviocytes Derived from Rheumatoid ArthritisBiomedicinesJanuary 30, 2025Ha-Reum Lee, Su-Jin Yoo, Jinhyun Kim, Seong Wook KangTransfection A specific siRNA duplex targeting LKB1 was purchased from Santa Cruz Biotechnology (Cat# sc-35816, Dallas, TX, USA). A control siRNA (Cat# sc-37007, Santa Cruz Biotechnology, Dallas, TX, USA) was used

(3) Novel role for tumor suppressor gene, liver kinase B1, in epithelial-mesenchymal transition leading to chronic lung allograft dysfunctionAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsMarch 1, 2022Rahman M, Ravichandran R, Bansal S, Sanborn K, Bowen S, Eschbacher J, Sureshbabu A, Fleming T, Bharat A, Walia R, et al.

(4) Endothelial cell-specific expression of serine/threonine kinase 11 modulates dendritic cell differentiationNature communicationsFebruary 3, 2022Zhao Q, Han YM, Song P, Liu Z, Yuan Z, Zou MH.transfection siRNAs targeting Ptbp1 (sc-38280), Sfpq (sc-38304), Hnrnpa1 (sc-270345), Hur (sc-35619), Lkb1 (sc-35816), and control siRNA (sc-37007) were obtained from Santa Cruz Biotechnology. The siRNA transfections

(5) Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancerCell death & diseaseMay 20, 2021Zhang D, Ning J, Okon I, Zheng X, Satyanarayana G, Song P, Xu S, Zou MH.overexpression transfection To knockdown endogenous gene expression, we purchased si-RNAs targeting human LKB1 (sc-35816), ALKBH5 (sc-93856), YTHDF2 (sc-78661), and CTCF (sc-35124) from Santa Cruz and transiently transfected

(6) Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytesMetabolism: clinical and experimentalApril 1, 2020Wei X, Wei X, Lu Z, Li L, Hu Y, Sun F, Jiang Y, Ma H, Zheng H, Yang G, et al.

(7) Sesamin Induces Endothelial Nitric Oxide Synthase Activation via Transient Receptor Potential Vanilloid Type 1Journal of agricultural and food chemistryMarch 18, 2020Pham TH, Jin SW, Lee GH, Park JS, Kim JY, Thai TN, Han EH, Jeong HG.

(8) Hispidulin Enhances TRAIL-Mediated Apoptosis via CaMKK/AMPK/USP51 Axis-Mediated Bim StabilizationCancersDecember 6, 2019Woo SM, Seo SU, Kim SH, Nam JO, Kim S, Park JW, Min KJ, Kwon TK.

(9) AZD1208, a Pan-Pim Kinase Inhibitor, Has Anti-Growth Effect on 93T449 Human Liposarcoma Cells via Control of the Expression and Phosphorylation of Pim-3, mTOR, 4EBP-1, S6, STAT-3 and AMPKInternational journal of molecular sciencesJanuary 16, 2019Yadav AK, Kumar V, Bailey DB, Jang BC.anti-Rabbit and goat anti-Mouse IgG antibodies, control siRNA (sc-37007), AMPK siRNA (sc-45312), LKB-1 siRNA (sc-35816) and Pim-3 siRNA (sc-61353) were purchased from Santa Cruz Biotechnology (Delaware, CA, USA). z-VAD-fmk

(10) LKB1 deficiency promotes proliferation and invasion of glioblastoma through activation of mTOR and focal adhesion kinase signaling pathwaysAmerican journal of cancer researchJanuary 1, 2019Zhang K, Wang J, Wang J, Luh F, Liu X, Yang L, Liu YR, Su L, Yang YS, Chu P, et al.

(11) Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1α/ERRα circuitPloS oneJanuary 1, 2018Choi YK, Park JH, Yun JA, Cha JH, Kim Y, Won MH, Kim KW, Ha KS, Kwon YG, Kim YM.

(12) LKB1 pro-oncogenic activity triggers cell survival in circulating tumor cellsMolecular oncologyNovember 1, 2017Trapp EK, Majunke L, Zill B, Sommer H, Andergassen U, Koch J, Harbeck N, Mahner S, Friedl TWP, Janni W, et al.Reagent (ThermoFisher Scientific) according to manufacturer's recommendations. The LKB1‐specific siRNA (sc‐35816) and the control nonspecific (NS)‐siRNA (sc‐36869) were purchased from Santa Cruz Biotechnologies (Santa

(13) 20S-Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1-AMP-activated protein kinase activationJournal of ginseng researchJuly 1, 2017Park SM, Jung EH, Kim JK, Jegal KH, Park CA, Cho IJ, Kim SC.

(14) HPV16 E6/E7 upregulates HIF-2α and VEGF by inhibiting LKB1 in lung cancer cellsTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineJuly 1, 2017Shao JS, Sun J, Wang S, Chung K, Du JT, Wang J, Qiu XS, Wang EH, Wu GP.(qRT-PCR). Small-interfering RNA HPV16 E6 small-interfering RNA (SiRNA; sc-156008), HPV16 E7 SiRNA (sc-270423), LKB1 SiRNA (sc-35816), and Control SiRNA (sc-37007) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). EPAS1

(15) EGFR probes matrix stiffnessNature cell biologyMay 31, 2017Rosenthal CK.

(16) WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagyNature communicationsMay 31, 2017Bakula D, Müller AJ, Zuleger T, Takacs Z, Franz-Wachtel M, Thost AK, Brigger D, Tschan MP, Frickey T, Robenek H, et al.

(17) 13-Ethylberberine reduces HMGB1 release through AMPK activation in LPS-activated RAW264.7 cells and protects endotoxemic mice from organ damageBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieFebruary 1, 2017Lee DU, Ko YS, Kim HJ, Chang KC.

(18) Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathwayBiochemical and biophysical research communicationsJanuary 22, 2017Li T, Liu D, Lei X, Jiang Q.

(19) Moutan Cortex Protects Hepatocytes against Oxidative Injury through AMP-Activated Protein Kinase PathwayBiological & pharmaceutical bulletinJanuary 1, 2017Jang MH, Kim KY, Song PH, Baek SY, Seo HL, Lee EH, Lee SG, Park KI, Ahn SC, Kim SC, et al.acids into cells. To knock down LKB1, cells were transfected with either a siRNA directed against LKB1 (SC-35816, Santa Cruz Biotechnology, Santa Cruz, CA, U.S.A.) or a non-targeting control siRNA (100 pmol/mL) using

(20) Activation of AMP-activated Protein Kinase by Metformin Induces Protein Acetylation in Prostate and Ovarian Cancer CellsThe Journal of biological chemistryNovember 25, 2016Galdieri L, Gatla H, Vancurova I, Vancura A.

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LKB1 siRNA (h)

LKB1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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LKB1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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