PGC-1α siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPGC-1α siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38885
Gene Nameperoxisome proliferator-activated receptor gamma, coactivator 1 alpha
Quantity10 µM
Speciesmouse
NCBI Full Gene Nameperoxisome proliferative activated receptor, gamma, coactivator 1 alpha
NCBI Gene AliasesA830037N07Rik, Gm11133, PGC-1, PPARGC-1-alpha, Pgc-1alpha, Pgc1, Pgco1, Ppargc1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Placental Mesenchymal Stem Cells Alleviate Podocyte Injury in Diabetic Kidney Disease by Modulating Mitophagy via the SIRT1-PGC-1alpha-TFAM PathwayInternational journal of molecular sciencesFebruary 28, 2023Han X, Wang J, Li R, Huang M, Yue G, Guan L, Deng Y, Cai W, Xu J.

(2) Ecklonia cava extracts decrease hypertension-related vascular calcification by modulating PGC-1α and SOD2Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieSeptember 1, 2022Byun KA, Oh S, Yang JY, Lee SY, Son KH, Byun K.

(3) PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor LesionsClinical cancer research : an official journal of the American Association for Cancer ResearchOctober 1, 2021Nimmakayala RK, Rauth S, Chirravuri Venkata R, Marimuthu S, Nallasamy P, Vengoji R, Lele SM, Rachagani S, Mallya K, Malafa MP, et al.

(4) Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose TissueDiabetesFebruary 1, 2020Gao P, Jiang Y, Wu H, Sun F, Li Y, He H, Wang B, Lu Z, Hu Y, Wei X, et al.Lipofectamine 3000 was 3.75 mL. Mouse siRNAs against Sirt3 (sc-61556), Mcu (sc-142052), AMPKa1/2 (sc45313), Pgc-1a (sc-38885), and negative control siRNA were purchased from Santa Cruz Biotechnology. The fulllength p300 expression

(5) Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathyTheranosticsJanuary 1, 2019Hu L, Ding M, Tang D, Gao E, Li C, Wang K, Qi B, Qiu J, Zhao H, Chang P, et al.Hamilton, 705RN, USA) into the left ventricle free wall (10 µl at each of four sites). PPARα siRNA (#sc-38885) was purchased from Santa Cruz Biotechnology (USA). For siRNA transfection, Lipofectamine™ RNAiMAX Transfection Reagent

(6) Glutathione Stimulates Vitamin D Regulatory and Glucose-Metabolism Genes, Lowers Oxidative Stress and Inflammation, and Increases 25-Hydroxy-Vitamin D Levels in Blood: A Novel Approach to Treat 25-Hydroxyvitamin D DeficiencyAntioxidants & redox signalingDecember 10, 2018Jain SK, Parsanathan R, Achari AE, Kanikarla-Marie P, Bocchini JA Jr.from Santa Cruz Biotechnology, Inc. (Dallas, TX), catalog numbers sc-41979 (GCLC), sc-36811 (VDR), and sc-38885 (PGC-1α). The control siRNA, a scrambled nonspecific RNA duplex that shares no sequence homology with

(7) Mild Hyperthermia-Induced Myogenic Differentiation in Skeletal Muscle Cells: Implications for Local Hyperthermic Therapy for Skeletal Muscle InjuryOxidative medicine and cellular longevityJanuary 1, 2018Lee H, Choi SJ.

(8) NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene programNature cell biologySeptember 1, 2017Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, Nakaki R, Suzuki K, Kobayashi H, Yamamoto S, et al.control siRNA and a siRNA for PGC1α or Adrb3 was purchased from Santa Cruz Biotechnology (sc-37007, sc-38885 and sc-39869). The siRNA were transfected using lipofectamine RNAiMAX (Invitrogen) 2 days before confluence,

(9) Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancyNature communicationsMay 5, 2017Wang F, Xu C, Reece EA, Li X, Wu Y, Harman C, Yu J, Dong D, Wang C, Yang P, et al.with the scramble control siRNA, the PKCα-siRNA (sc-35960, Santa Cruz Biotechnology), the PGC1α-siRNA (sc-38885) or the control siRNA using Lipofectamine RNAiMAX (Invitrogen) according to the manufacture's protocol.

(10) Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cellsJournal of pineal researchOctober 1, 2016Li M, Pi H, Yang Z, Reiter RJ, Xu S, Chen X, Chen C, Zhang L, Yang M, Li Y, et al.

(11) PGC-1α Promotes Ureagenesis in Mouse Periportal Hepatocytes through SIRT3 and SIRT5 in Response to GlucagonScientific reportsApril 7, 2016Li L, Zhang P, Bao Z, Wang T, Liu S, Huang F.sc-61556, Santa Cruz); SIRT5 siRNA (Production no. sc-63027, Santa Cruz); PGC-1α siRNA (Production no. sc-38885, Santa Cruz) and scrambled (SCR, as control, Sigma-Aldrich) according to the manufacturer’s instructions.

(12) PGC-1α/ERRα-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase βAntioxidants & redox signalingFebruary 20, 2016Zhang X, Ren X, Zhang Q, Li Z, Ma S, Bao J, Li Z, Bai X, Zheng L, Zhang Z, et al.

(13) Decreased Gluconeogenesis in the Absence of Cystathionine Gamma-Lyase and the Underlying MechanismsAntioxidants & redox signalingJanuary 20, 2016Untereiner AA, Wang R, Ju Y, Wu L.

(14) Dietary iron controls circadian hepatic glucose metabolism through heme synthesisDiabetesApril 1, 2015Simcox JA, Mitchell TC, Gao Y, Just SF, Cooksey R, Cox J, Ajioka R, Jones D, Lee SH, King D, et al.Knockdown of PGC-1α was accomplished by PGC-1α small interfering RNA (siRNA) from Santa Cruz Biotechnology (sc-38885), following the company’s general protocol with control siRNA (sc-37007) and transfection reagent (sc-29528). RT-PCR RNA

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PGC-1α siRNA (m)

PGC-1α siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PGC-1α siRNA (m) from Santa Cruz Biotechnology, Inc.

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