Notch 2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNotch 2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-40135
Gene NameNotch gene homolog 2 (Drosophila)
Quantity10 µM
Specieshuman
NCBI Full Gene Namenotch receptor 2
NCBI Gene AliasesAGS2, HJCYS, hN2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Atomoxetine suppresses radioresistance in glioblastoma via circATIC/miR-520d-5p/Notch2-Hey1 axisCell Communication and SignalingNovember 5, 2024Hyun Jeong Seok, Jae Yeon Choi, Dong Hyeon Lee, Incheol Shin, In Hwa Bae+) CircRNA Mini Vector (Plasmid #60648) from addgene and created an overexpression vector. siNotch2 (sc-40135) and siHey1 (sc-37914) were purchased from Santa Cruz Biotechnology. Transfection was performed using

(2) NOTCH2 participates in Jagged1-induced osteogenic differentiation in human periodontal ligament cellsScientific reportsAugust 7, 2020Manokawinchoke J, Sumrejkanchanakij P, Boonprakong L, Pavasant P, Egusa H, Osathanon T.

(3) Constitutive activation of Notch2 signalling confers chemoresistance to neural stem cells via transactivation of fibroblast growth factor receptor-1Stem cell researchMarch 1, 2019Tomé M, Tchorz J, Gassmann M, Bettler B.

(4) DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch SignalingFrontiers in oncologyJanuary 1, 2019Feng J, Wang J, Liu Q, Li J, Zhang Q, Zhuang Z, Yao X, Liu C, Li Y, Cao L, et al.serum (Gibco, Auckland, USA) in a humidified incubator at 37°C with 5% CO2. Notch2-targeted shRNA (sc-40135) was obtained from Santa Cruz Biotech (Santa Cruz, CA, USA). Transfection was performed using lipofectamine 3000

(5) miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLCStem cell research & therapyNovember 23, 2018Wang X, Meng Q, Qiao W, Ma R, Ju W, Hu J, Lu H, Cui J, Jin Z, Zhao Y, et al.

(6) miR-93-5p suppresses cellular senescence by directly targeting Bcl-w and p21Biochemical and biophysical research communicationsNovember 10, 2018Choi JY, Shin HJ, Bae IH.

(7) Indirect immobilized Jagged1 suppresses cell cycle progression and induces odonto/osteogenic differentiation in human dental pulp cellsScientific reportsAugust 31, 2017Manokawinchoke J, Nattasit P, Thongngam T, Pavasant P, Tompkins KA, Egusa H, Osathanon T.

(8) Notch Signaling Participates in TGF-β-Induced SOST Expression Under Intermittent Compressive StressJournal of cellular physiologyAugust 1, 2017Manokawinchoke J, Sumrejkanchanakij P, Pavasant P, Osathanon T.

(9) Pathobiology of Notch2 in lung cancerPathologyAugust 1, 2017Motooka Y, Fujino K, Sato Y, Kudoh S, Suzuki M, Ito T.

(10) Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitroOncotargetMarch 28, 2017Li Y, Ye J, Chen Z, Wen J, Li F, Su P, Lin Y, Hu B, Wu D, Ning L, et al.(West Berkeley, CA, USA). The transfection of Notch2-small interfering RNA (siRNA) Notch2-siRNA (sc-40135, Santa Cruz Biotechnology, Inc) is the target-specific 19-25 nt siRNA designed to knock down human Notch2

(11) Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted TherapyClinical cancer research : an official journal of the American Association for Cancer ResearchJune 15, 2016Hayashi T, Gust KM, Wyatt AW, Goriki A, Jäger W, Awrey S, Li N, Oo HZ, Altamirano-Dimas M, Buttyan R, et al.

(12) The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanateBreast cancer research and treatmentFebruary 1, 2015Kim SH, Singh SV.

(13) Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cellsBreast cancer research and treatmentAugust 1, 2014Sehrawat A, Sakao K, Singh SV.

(14) MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expressionJournal of neuro-oncologyMarch 1, 2013Chen L, Chen XR, Zhang R, Li P, Liu Y, Yan K, Jiang XD.

(15) Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cellsBreast cancer research and treatmentNovember 1, 2012Lee J, Sehrawat A, Singh SV.

(16) Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migrationBreast cancer research and treatmentAugust 1, 2012Kim SH, Sehrawat A, Singh SV.

(17) Notch activation is dispensable for D, L-sulforaphane-mediated inhibition of human prostate cancer cell migrationPloS oneJanuary 1, 2012Hahm ER, Chandra-Kuntal K, Desai D, Amin S, Singh SV.

(18) Density of human bone marrow stromal cells regulates commitment to vascular lineagesStem cell researchMay 1, 2011Whyte JL, Ball SG, Shuttleworth CA, Brennan K, Kielty CM.were used for VEGF-A knockdown (Qiagen). For Notch knockdowns, siRNAs for Notch1 (sc-36095), Notch2 (sc-40135), and Notch3 (sc-37135) (Santa Cruz, USA) were employed, with scrambled siRNA as a control (Qiagen). Immunoprecipitation

(19) Identification and validation of Notch pathway activating compounds through a novel high-throughput screening methodCancerApril 1, 2011Pinchot SN, Jaskula-Sztul R, Ning L, Peters NR, Cook MR, Kunnimalaiyaan M, Chen H.analyzed. Notch RNAi Assays siRNA against Notch1 or Notch2 and nonspecific siRNA (Santa Cruz, sc-44226, sc-40135, sc-40986, and sc-37007) were transfected into BON GI carcinoid cells using Lipofectamine 2000 (Invitrogen). Quantitative Real-Time PCR

(20) Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migrationPloS oneJanuary 1, 2011Kim SH, Sehrawat A, Sakao K, Hahm ER, Singh SV.

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Notch 2 siRNA (h)

Notch 2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Notch 2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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