GRP 78 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemGRP 78 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29338
Gene Nameheat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Quantity10 µM
Specieshuman
NCBI Full Gene Nameheat shock protein family A (Hsp70) member 5
NCBI Gene AliasesBIP, GRP78, HEL-S-89n
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Combined downregulation of TGF-β1 and GRP78 is responsible for overcoming acquired sorafenib resistance, which is initiated by rewiring the cell surface CD44-GRP78-IGF-1R signaling circuitCancer Gene TherapyJuly 9, 2025Shengji Li, Geun-Hyeok Oh, Jeong A. Hong, Soojin Choi, Minseo Kim, Hyeji Kwon, Seung-Kyun Ko, Sun Jun Park, Hee Kyung Kim, Hye Jin Choi, et al.Sorafenib (Cat# SML2653) and MG132 (Cat#474787) were purchased from Sigma‒Aldrich, and GRP78 siRNA (Cat#sc-29338) was purchased from Santa Cruz Biotechnology. AEBSF (Cat#A-540) was purchased from Gold Biotechnology

(2) Clusterin can mediate apoptosis-induced molecular mechanisms in immune thrombocytopeniaBlood Vessels, Thrombosis & HemostasisSeptember 1, 2024Tea Stein, Christina Bitsina, Michelle Seiler, Markus Schmugge, Francesca D. Franzosoin a 24-well plate. MEG-01 cells were incubated with siRNAs gene against CLU (sc-43688) and GRP78 (sc-29338), or negative control siRNA (sc-44230, using siRNA transfection reagent [sc-29528], siRNA transfection medium

(3) Paeoniflorin Induces ER Stress-Mediated Apoptotic Cell Death by Generating Nox4-Derived ROS under Radiation in Gastric CancerNutrientsDecember 13, 2023Tae Woo Kimtarget PERK (Bioneer; 1649-1), CHOP (Santa Cruz; sc-36213), Nox4 (Santacruz), and GRP78 (Santa Cruz; sc-29338) using Lipofectamine 2000 (Invitrogen, Carlsbad, CA, USA) following the manufacturer’s manual. 2.11.

(4) Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver CancerInternational journal of molecular sciencesMay 22, 2023Kim TW.(Bioneer; 1649-1, Daejeon, Republic of Korea), PERK (Santa Cruz; sc-36213), and GRP78 (Santa Cruz; sc-29338) for 24 h using Lipofectamine 2000 reagent (Invitrogen, Carlsbad, CA, USA) according to the manufacturer’s

(5) Targeting ER Stress with Saikosaponin A to Overcome Resistance under Radiation in Gastric Cancer CellsInternational journal of molecular sciencesMarch 16, 2023Kim TW.plate were transfected with double-stranded siRNAs (30 nmol/mL, Santa Cruz) against GRP78 (Santa Cruz; sc-29338), PERK (Santa Cruz; sc-36213), Nox4 (Santa Cruz; sc-41586), and CHOP (Bioneer; 1649-1) and shRNAs against

(6) BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1iScienceDecember 22, 2022Hromas R, Srinivasan G, Yang M, Jaiswal A, Totterdale TA, Phillips L, Kirby A, Khodayari N, Brantley M, Williamson EA, et al.

(7) Hepatocyte steatosis inhibits hepatitis B virus secretion via induction of endoplasmic reticulum stressMolecular and cellular biochemistryNovember 1, 2022Liu Q, Mu M, Chen H, Zhang G, Yang Y, Chu J, Li Y, Yang F, Lin S.

(8) Siah2-GRP78 interaction regulates ROS and provides a proliferative advantage to Helicobacter pylori-infected gastric epithelial cancer cellsCellular and molecular life sciences : CMLSJuly 11, 2022Dixit P, Suratkal SS, Kokate SB, Chakraborty D, Poirah I, Samal S, Rout N, Singh SP, Sarkar A, Bhattacharyya A.

(9) GRP78/BiP determines senescence evasion cell fate after cisplatin-based chemotherapyScientific reportsNovember 17, 2021Ei ZZ, Choochuay K, Tubsuwan A, Pinkaew D, Suksomtip M, Vinayanuwattikun C, Chanvorachote P, Chunhacha P.

(10) Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the UPR in models of neurodegenerationMolecular therapy : the journal of the American Society of Gene TherapyMay 5, 2021Vidal RL, Sepulveda D, Troncoso-Escudero P, Garcia-Huerta P, Gonzalez C, Plate L, Jerez C, Canovas J, Rivera CA, Castillo V, et al.

(11) Miconazole induces autophagic death in glioblastoma cells via reactive oxygen species-mediated endoplasmic reticulum stressOncology lettersApril 1, 2021Jung HJ, Seo I, Jha BK, Suh SI, Baek WK.Biosciences). Small interfering RNA (siRNA) transfection siRNAs against ATG5 (cat. no. sc-41445) and BiP (cat. no. sc-29338), and a scrambled siRNA (cat. no. sc-37007) were obtained from Santa Cruz Biotechnology, Inc. The sequence

(12) Cryptotanshinone-Induced p53-Dependent Sensitization of Colon Cancer Cells to Apoptotic Drive by Regulation of Calpain and Calcium HomeostasisThe American journal of Chinese medicineJanuary 1, 2020Wang Y, Zhang Z, Auyeung KK, Cho CH, Yung KK, Ko JK.

(13) Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapyTheranosticsJanuary 1, 2020Liao Y, Liu Y, Xia X, Shao Z, Huang C, He J, Jiang L, Tang D, Liu J, Huang H.siRNA-lipofectamine mixtures were then added in each group for 48 h for further analysis. The GRP78 siRNAs (#sc-29338) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA). The siRNA sequences are listed below

(14) Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthmaBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieOctober 1, 2019Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, Wang Z, Tan N.

(15) Downregulation of glucose-regulated protein 78 enhances the cytotoxic effects of curcumin on human nasopharyngeal carcinoma cellsInternational journal of molecular medicineNovember 1, 2018Yu X, Shi L, Yan L, Wang H, Wen Y, Zhang X.a light microscope (Olympus Corporation, Tokyo, Japan). RNA interference. GRP78‑specific (cat. no. sc‑29338) and non‑silencing scrambled siRNA (cat. no. sc‑37007) were obtained from Santa Cruz Biotechnology, Inc

(16) Crosstalk Between Apoptosis and Autophagy Is Regulated by the Arginylated BiP/Beclin-1/p62 ComplexMolecular cancer research : MCRJuly 1, 2018Song X, Lee DH, Dilly AK, Lee YS, Choudry HA, Kwon YT, Bartlett DL, Lee YJ.

(17) O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistanceCell death & diseaseMay 1, 2018Liu Y, Cao Y, Pan X, Shi M, Wu Q, Huang T, Jiang H, Li W, Zhang J.manufacturer’s instructions. OGT siRNA (sc-40780), GFAT siRNA (sc-6068), XBP1 siRNA (sc-38627), GRP78 siRNA (sc-29338) and scrambled siRNA (sc-37007) were obtained from Santa Cruz Biotechnology (CA, USA). Transfection

(18) Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epitheliumInternational journal of chronic obstructive pulmonary diseaseJanuary 1, 2018Wang Y, Zhou JS, Xu XC, Li ZY, Chen HP, Ying SM, Li W, Shen HH, Chen ZH.

(19) Protodioscin Induces Apoptosis Through ROS-Mediated Endoplasmic Reticulum Stress via the JNK/p38 Activation Pathways in Human Cervical Cancer CellsCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Lin CL, Lee CH, Chen CM, Cheng CW, Chen PN, Ying TH, Hsieh YH.

(20) GRP78 protects a disintegrin and metalloprotease 17 against protein-disulfide isomerase A6 catalyzed inactivationFEBS lettersNovember 1, 2017Schäfer M, Granato DC, Krossa S, Bartels AK, Yokoo S, Düsterhöft S, Koudelka T, Scheidig AJ, Tholey A, Paes Leme AF, et al.

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GRP 78 siRNA (h)

GRP 78 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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GRP 78 siRNA (h) from Santa Cruz Biotechnology, Inc.

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