p53 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemp53 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29436
Gene Nametransformation related protein 53
Quantity10 µM
Speciesmouse
NCBI Full Gene Nametransformation related protein 53
NCBI Gene AliasesTp53, bbl, bfy, bhy, p44, p53
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) CREB2 Functions as a Central Mediator of Oxidative Neuronal Death Triggered by Microglial Glutamate Release Under Neuroinflammatory ConditionsCellular and Molecular NeurobiologyFebruary 13, 2026Uk Yeol Moon, Young Eun Kim, Huu Dat Nguyen, Hye Joung Choiexamined using mouse-specific siRNAs targeting GADD45α (sc-35439), CREB2/ATF4 (sc-35113), and p53 (sc-29436), along with a control siRNA (sc-37007) (Santa Cruz Biotechnology). HT22 cells were seeded to achieve

(2) Chronic Viral Mimicry Induction following p53 Loss Promotes Immune EvasionCancer DiscoveryApril 2, 2025Charles A. Ishak, Sajid A. Marhon, Naïri Tchrakian, Anjelica Hodgson, Helen Loo Loo Yau, Isabela M. Gonzaga, Melanie Peralta, Ilinca M. Lungu, Stephanie Gomez, Sheng-Ben Liang, et al.prior to harvesting for RNA or protein. siRNAs used in this study include p53 siRNA (m) (Santa Cruz sc-29436) and control siRNA-A (Santa Cruz sc-37007). CRISPR Knockout CRISPR gene editing was performed using

(3) SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicityCell Death DisMarch 31, 2025Xu Yang, Yingjie Guan, George Bayliss, Ting C. Zhao, Shougang ZhuangCell Signaling Technology (Danvers, MA, USA). con siRNA (sc-37007), SET8 siRNA (sc-155946), and p53 siRNA (sc-29436) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). The primary antibodies utilized for Western blotting

(4) SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicityResearch SquareAugust 28, 2024Xu Yang, Yingjie Guan, George Bayliss, Ting C. Zhao, Shougang ZhuangCell Signaling Technology (Danvers, MA, USA). con siRNA (sc-37007), SET8 siRNA (sc-155946), and p53 siRNA (sc-29436) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). The primary antibodies utilized for Western blotting

(5) Heat stress suppresses MnSOD expression via p53-Sp1 interaction and induces oxidative stress damage in endothelial cells: Protective effects of MitoQ10 and Pifithrin-αHeliyonDecember 1, 2023Jian Gong, Peipei Sun, Li Li, Zhimin Zou, Qihua Wu, Liyun Sun, Hui Li, Zhengtao Gu, Lei Sugene silencing and transfection Scrambled RNA controls (SC-36869, Santa Cruz), Tp53-targeted siRNAs (SC-29436, Santa Cruz), and Sp1 targeted siRNA (sc-29488, Santa Cruz Biotechnology) were transfected into MAECs

(6) p53 Regulates Mitochondrial Dynamics in Vascular Smooth Muscle Cell CalcificationInternational journal of molecular sciencesJanuary 13, 2023Phadwal K, Tang QY, Luijten I, Zhao JF, Corcoran B, Semple RK, Ganley IG, MacRae VE.assessed by HCl leaching [18]. 4.3. Transfection Assays Cells were transfected with 80 pmol murine p53 (SC-29436; Santa Cruz Biotechnology, Dallas, TX, USA) or scrambled control siRNA (SC-37007; Santa Cruz Biotechnology)

(7) A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effectsPharmacological researchJanuary 1, 2023Aguilar-Recarte D, Barroso E, Zhang M, Rada P, Pizarro-Delgado J, Peña L, Palomer X, Valverde ÁM, Wahli W, Vázquez-Carrera M.

(8) LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axisBiology directNovember 16, 2022Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, et al.GenePharma (Shanghai, China), and the specific siRNA for p53 was purchased from Santa Cruz (Catalog number: sc-29436). For upregulating of target genes, overexpression plasmids from GenePharma Company (Shanghai, China)

(9) Histone methyltransferase MLL1 drives renal tubular cell apoptosis by p53-dependent repression of E-cadherin during cisplatin-induced acute kidney injuryCell death & diseaseSeptember 6, 2022Zhang C, Guan Y, Zou J, Yang X, Bayliss G, Zhuang S.(MO, USA). Klotho antibody (sc-515942), WDR5 siRNA (sc-61799), E-cadherin siRNA (sc-35243), p53 siRNA (sc-29436), and negative siRNA (sc-37007) were purchased from Santa Cruz Biotechnology (CA, USA). Animals models

(10) p53 missense mutant G242A subverts natural killer cells in sheltering mouse breast cancer cells against immune rejectionExperimental cell researchAugust 1, 2022Uddin MB, Roy KR, Hill RA, Roy SC, Gu X, Li L, Zhang QJ, You Z, Liu YY.

(11) Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitroFrontiers in PhysiologyJanuary 21, 2022Ling Ruan, Bharati Mendhe, Emily Parker, Andrew Kent, Carlos M. Isales, William D. Hill, Meghan McGee-Lawrence, Sadanand Fulzele, Mark W. Hamrick(siRNA ID # n253517, Ambion) used for MALAT1 transfection. siRNA for P53 was from Santa Cruz (Cat. #SC-29436). In brief, cells were monitored after 48 h in culture and transfection performed on 75–80% confluent

(12) GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPKCell reportsAugust 10, 2021Aguilar-Recarte D, Barroso E, Gumà A, Pizarro-Delgado J, Peña L, Ruart M, Palomer X, Wahli W, Vázquez-Carrera M.

(13) Luteolin inhibits H(2)O(2)-induced cellular senescence via modulation of SIRT1 and p53The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of PharmacologyJuly 1, 2021Zhu RZ, Li BS, Gao SS, Seo JH, Choi BM.Cell Signaling Technology, 9101), and phospho-p38 (p-p38, Cell Signaling Technology, 9211). The specific siRNA for p53 (sc-29436) and SIRT1 (sc-40987) was purchased from Santa Cruz Biotechonology (Santa Cruz, CA, USA). Unless indicated

(14) Ethylmalonic encephalopathy 1 initiates overactive autophagy in depleted uranium-induced cytotoxicity in the human embryonic kidney 293 cellsJournal of biochemical and molecular toxicologyMarch 1, 2021Hao Y, Huang J, Ran Y, Wang S, Li J, Zhao Y, Ran X, Lu B, Liu J, Li R.

(15) Role of ferroptosis in the process of diabetes-induced endothelial dysfunctionWorld journal of diabetesFebruary 15, 2021Luo EF, Li HX, Qin YH, Qiao Y, Yan GL, Yao YY, Li LQ, Hou JT, Tang CC, Wang D.according to the manufacturer’s instructions. siRNA specic for p53 was purchased from Santa Cruz (sc-29436, United States). Control siRNA of p53 was purchased from Santa Cruz (sc-37007, United States). Real-time

(16) Metformin: a novel promising option for fertility preservation during cyclophosphamide-based chemotherapyMolecular human reproductionJanuary 22, 2021Huang CC, Chou CH, Yang YS, Ho HN, Shun CT, Wen WF, Chen SU, Chen MJ.experiments. The targeted siRNAs for p21, p53 and control were from Santa Cruz Biotechnology; sc-29428, sc-29436 and sc-36869, respectively. The request for siRNA sequences was declined by Santa Cruz. Statistical

(17) Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerinCell death and differentiationJanuary 1, 2021Velletri T, Huang Y, Wang Y, Li Q, Hu M, Xie N, Yang Q, Chen X, Chen Q, Shou P, et al.

(18) p53 Hinders CRISPR/Cas9-Mediated Targeted Gene Disruption in Memory CD8 T Cells In VivoJournal of immunology (Baltimore, Md. : 1950)October 15, 2020Kurup SP, Moioffer SJ, Pewe LL, Harty JT.of Nucleofector buffer (Lonza) along with the RNP complex, with or without the p53siRNA (Santa Cruz, sc-29436) in a glass cuvette (Lonza). Nucleofector 2b device (Lonza) with Nucleofector program X001 was used.

(19) 4-Hydroxyestrone, an Endogenous Estrogen Metabolite, Can Strongly Protect Neuronal Cells Against Oxidative DamageScientific reportsApril 29, 2020Choi HJ, Lee AJ, Kang KS, Song JH, Zhu BT.GADD45α and p53, respectively. The siGADD45α (catalog no. sc-35439, Santa Cruz, CA), sip53 (catalog no. sc-29436, Santa Cruz), and siRNA negative control (catalog no. sc-37007, Santa Cruz) are purchased from Santa

(20) RNA helicase p68 inhibits the transcription and post-transcription of Pkd1 in ADPKDTheranosticsJanuary 1, 2020Zhang L, Li LX, Zhou JX, Harris PC, Calvet JP, Li X.

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p53 siRNA (m)

p53 siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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p53 siRNA (m) from Santa Cruz Biotechnology, Inc.

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