LXRα siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemLXRα siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-38828
Gene Namenuclear receptor subfamily 1, group H, member 3
Quantity10 µM
Specieshuman
NCBI Full Gene Namenuclear receptor subfamily 1 group H member 3
NCBI Gene AliasesLXR-a, LXRA, RLD-1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Oridonin restores hepatic lipid homeostasis in an LXRα-ATGL/EPT1 axis-dependent mannerJournal of Pharmaceutical AnalysisNovember 1, 2023Yulian Chen, Huanguo Jiang, Zhikun Zhan, Jindi Lu, Tanwei Gu, Ping Yu, Weimin Liang, Xi Zhang, Shilong Zhong, Lan TangXi'an Qiyue Biotechnology Co., Ltd (Xi'an, China). The small interfering RNA (siRNA) specific for LXRα (sc-38828), ATGL (sc-60223) and EPT1 (sc-61516), and negative control siRNA (sc-37007) were obtained from Santa Cruz Biotechnology

(2) Restoration of lipid homeostasis between TG and PE by the LXRα-ATGL/EPT1 axis ameliorates hepatosteatosisCell death & diseaseFebruary 6, 2023Chen Y, Jiang H, Zhan Z, Lu J, Gu T, Yu P, Liang W, Zhang X, Liu S, Bi H, et al.cy7-labeled cholesterol were purchased from Xi’an Qiyue Biotechnology Co., Ltd. The siRNA specific for LXRα (sc-38828), and negative control siRNA (sc-37007) were obtained from Santa Cruz Biotechnology (Dallas, TX, USA).

(3) Adiponectin Stimulates Apolipoprotein A-1 Gene Expression in HepG2 Cells via AMPK, PPARα, and LXRs Signaling MechanismsBiochemistry. BiokhimiiaNovember 1, 2022Tanyanskiy DA, Shavva VS, Dizhe EB, Oleinikova GN, Lizunov AV, Nekrasova EV, Mogilenko DA, Larionova EE, Orlov SV, Denisenko AD.

(4) Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate CancerCancersJune 24, 2022Yang N, Yang Y, Huang Z, Chen HW.NR1H3 siRNA, s14685; NR1H2 siRNA, s19568) or Santa Cruz Biotechnology (Dallas, TX, USA; LXRα siRNA, sc-38828; LXRβ siRNA, sc-45316). Transfections were performed with DharmaFECT#1 (Dharmacon, Lafayette, CO, USA)

(5) LXRα Regulates oxLDL-Induced Trained Immunity in MacrophagesInternational journal of molecular sciencesMay 31, 2022Findeisen HM, Voges VC, Braun LC, Sonnenberg J, Schwarz D, Körner H, Reinecke H, Sohrabi Y.THP-1 cells were transfected with 30 nM small interfering RNA (siRNA) for LXRα (Santa Cruz, Dallas, TX, USA, #sc- 38828), LXRβ (Santa Cruz, #sc-45316), SREBP1 (Santa Cruz, Dallas, TX, USA, #sc-36557), SREBP2 (Santa Cruz,

(6) Oridonin alleviates hyperbilirubinemia through activating LXRα-UGT1A1 axisPharmacological researchApril 1, 2022Zhan Z, Dai F, Zhang T, Chen Y, She J, Jiang H, Liu S, Gu T, Tang L.

(7) LXR-Mediated Regulation of Marine-Derived Piericidins Aggravates High-Cholesterol Diet-Induced Cholesterol Metabolism Disorder in MiceJournal of medicinal chemistryJuly 22, 2021Liang Z, Chen Y, Gu T, She J, Dai F, Jiang H, Zhan Z, Li K, Liu Y, Zhou X, et al.

(8) Regulation of cytochrome P450 4F11 expression by liver X receptor alphaInternational immunopharmacologyJanuary 1, 2021Zhang T, Zhan Z, Chen Y, Chen J, Han W, Liang Z, Liu Q, Liu S, Tang L.

(9) Liver X receptor inhibits the growth of hepatocellular carcinoma cells via regulating HULC/miR-134-5p/FOXM1 axisCellular signallingOctober 1, 2020He J, Yang T, He W, Jiang S, Zhong D, Xu Z, Wei Q, Zhang Y, Shi C.

(10) Reduced Sirtuin1 signalling exacerbates diabetic mice hindlimb ischaemia injury and inhibits the protective effect of a liver X receptor agonistJournal of cellular and molecular medicineMay 1, 2020Fan W, Zhang R, Han D, Jiang Z, Li S, Zhang J, Li Y, Wang Y, Cao F.

(11) Activation of LXRɑ/β by cholesterol in malignant ascites promotes chemoresistance in ovarian cancerBMC cancerDecember 10, 2018Kim S, Lee M, Dhanasekaran DN, Song YS.

(12) Tumor necrosis factor α stimulates endogenous apolipoprotein A-I expression and secretion by human monocytes and macrophages: role of MAP-kinases, NF-κB, and nuclear receptors PPARα and LXRsMolecular and cellular biochemistryNovember 1, 2018Shavva VS, Mogilenko DA, Nekrasova EV, Trulioff AS, Kudriavtsev IV, Larionova EE, Babina AV, Dizhe EB, Missyul BV, Orlov SV.

(13) Dihydromyricetin ameliorates foam cell formation via LXRα-ABCA1/ABCG1-dependent cholesterol efflux in macrophagesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieMay 1, 2018Zeng Y, Peng Y, Tang K, Wang YQ, Zhao ZY, Wei XY, Xu XL.

(14) Tribbles homolog 1 enhances cholesterol efflux from oxidized low-density lipoprotein-loaded THP-1 macrophagesExperimental and therapeutic medicineJuly 1, 2017Fu Y, Zhao Y, Huang B.

(15) Liver X receptor activation inhibits PC-3 prostate cancer cells via the beta-catenin pathwayPathology, research and practiceMarch 1, 2017Youlin K, Li Z, Weiyang H, Jian K, Siming L, Xin G.

(16) Insulin-Mediated Downregulation of Apolipoprotein A-I Gene in Human Hepatoma Cell Line HepG2: The Role of Interaction Between FOXO1 and LXRβ Transcription FactorsJournal of cellular biochemistryFebruary 1, 2017Shavva VS, Bogomolova AM, Nikitin AA, Dizhe EB, Tanyanskiy DA, Efremov AM, Oleinikova GN, Perevozchikov AP, Orlov SV.

(17) Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent MannerCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2017Jiang T, Ren K, Chen Q, Li H, Yao R, Hu H, Lv YC, Zhao GJ.

(18) Allicin Decreases Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Umbilical Vein Endothelial Cells through Suppression of Mitochondrial Dysfunction and Activation of Nrf2Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2017Zhang M, Pan H, Xu Y, Wang X, Qiu Z, Jiang L.transfected with LXRα siRNA (5 nM) or control siRNA (5 nM) (Santa Cruz Biotechnology Inc., CA, USA, Cat: sc-38828) using the DharmaFECT transfection reagent (Thermo Scientific Dharmacon, USA) for 36 h. Then, the cells

(19) Anti-atherosclerotic potential of baicalin mediated by promoting cholesterol efflux from macrophages via the PPARγ-LXRα-ABCA1/ABCG1 pathwayBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieOctober 1, 2016He XW, Yu D, Li WL, Zheng Z, Lv CL, Li C, Liu P, Xu CQ, Hu XF, Jin XP.

(20) IRAK regulates macrophage foam cell formation by modulating genes involved in cholesterol uptake and effluxBioEssays : news and reviews in molecular, cellular and developmental biologyJuly 1, 2016Rana M, Kumar A, Tiwari RL, Singh V, Chandra T, Dikshit M, Barthwal MK.

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LXRα siRNA (h)

LXRα siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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LXRα siRNA (h) from Santa Cruz Biotechnology, Inc.

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