NQO1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNQO1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37139
Quantity10 µM
Gene NameNAD(P)H dehydrogenase, quinone 1
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene NameNAD(P)H quinone dehydrogenase 1
NCBI Gene AliasesDHQU, DIA4, DTD, NMOR1, NMORI, QR1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Effect of NQO1 Downregulation on the Migration and Invasion of HPV16-Positive Cervical Cancer CellsAsian Pacific Journal of Cancer PreventionDecember 1, 2024Warattaya Wattanathavorn, Supranee Buranapraditkun, Nakarin Kitkumthorn, Parvapan Bhattarakosol, Arkom ChaiwongkotTransfection SiRNA transfection was performed using Lipofectamine RNAi MAX reagent (Invitrogen, USA). NQO1 siRNA (sc-37139, Santa Cruz Biotechnology) and non-targeting control (NTC) siRNA (D-001810-01-20, Horizon) were used.

(2) Effect of NQO1 Downregulation on the Migration and Invasion of HPV16-Positive Cervical Cancer CellsAsian Pac J Cancer PrevJanuary 1, 2024Warattaya Wattanathavorn, Supranee Buranapraditkun, Nakarin Kitkumthorn, Parvapan Bhattarakosol, Arkom ChaiwongkotTransfection SiRNA transfection was performed using Lipofectamine RNAi MAX reagent (Invitrogen, USA). NQO1 siRNA (sc-37139, Santa Cruz Biotechnology) and non-targeting control (NTC) siRNA (D-001810-01-20, Horizon) were used.

(3) NAD(P)H Quinone Oxidoreductase-1 Expression Promotes Self-Renewal and Therapeutic Resistance in Non-Small Cell Lung CancerGenesFebruary 28, 2023Madajewski B, Boatman MA, Martinez I, Carter JH, Bey EA.retroviral vector (Open Biosystems, RHS1764-9691437), and lentiviral particles (Santa Cruz Biotechnology, sc-37139) were used to generate stable knockdown cell lines (shNQO1, shNQO1 (lenti)) and empty vector controls

(4) The Potential Key Role of the NRF2/NQO1 Pathway in the Health Effects of Arsenic Pollution on SCCInternational journal of environmental research and public healthJuly 1, 2022Yang Q, Yan R, Mo Y, Xia H, Deng H, Wang X, Li C, Kato K, Zhang H, Jin T, et al.

(5) Sustained high expression of NRF2 and its target genes induces dysregulation of cellular proliferation and apoptosis is associated with arsenite-induced malignant transformation of human bronchial epithelial cellsThe Science of the total environmentFebruary 20, 2021Kong Q, Deng H, Li C, Wang X, Shimoda Y, Tao S, Kato K, Zhang J, Yamanaka K, An Y.

(6) DNA damage induced by KP372-1 hyperactivates PARP1 and enhances lethality of pancreatic cancer cells with PARP inhibitionScientific reportsNovember 19, 2020Viera T, Patidar PL.

(7) Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastomaJournal of hematology & oncologyOctober 21, 2020Lei K, Gu X, Alvarado AG, Du Y, Luo S, Ahn EH, Kang SS, Ji B, Liu X, Mao H, et al.a fluorescence microscope (Nikon, Japan). Transfection and infection of the cells The NQO1-siRNA(#sc-37139), GSTP1-siRNA (#sc-72091) and nontargeting siRNA (#sc-37007) as control were purchased from Santa Cruz Biotechnology

(8) NADPH-quinone oxidoreductase-1 mediates Benzo-[a]-pyrene-1,6-quinone-induced cytotoxicity and reactive oxygen species production in human EA.hy926 endothelial cellsToxicology and applied pharmacologyOctober 1, 2020Shukla H, Gaje G, Koucheki A, Lee HY, Sun X, Trush MA, Zhu H, Li YR, Jia Z.

(9) Petatewalide B alleviates oxygen‑glucose deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathwayMolecular medicine reportsJuly 1, 2020Park SY, Cho MH, Li M, Li K, Park G, Choi YW.

(10) Characterization of a highly specific NQO1-activated near-infrared fluorescent probe and its application for in vivo tumor imagingScientific reportsJune 12, 2019Punganuru SR, Madala HR, Arutla V, Zhang R, Srivenugopal KS.and used without further purification. NQO1 was purchased from Sigma-Aldrich (D1515). NQO1 siRNA (h) (sc-37139) and NQO1 (A180) (sc-32793) antibodies were purchased from Santa Cruz. All cell lines were obtained

(11) Cancer-Specific Biomarker hNQO1-Activatable Fluorescent Probe for Imaging Cancer Cells In Vitro and In VivoCancersNovember 28, 2018Punganuru SR, Madala HR, Arutla V, Srivenugopal KS.USA) or Fisher Scientific (Hampton, NH, USA) and used without further purification. NQO1 siRNA (h) (sc-37139) and NQO1 (A180) (sc-32793) antibodies were purchased from Santa Cruz (Santa Cruz Biotechnology Inc,

(12) NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activityFree radical biology & medicineOctober 1, 2018Kang HJ, Song HY, Ahmed MA, Guo Y, Zhang M, Chen C, Cristofanilli M, Horiuchi D, Vassilopoulos A.SIRT2 and cell cycle related proteins constructs have been described previously [14]. siNQO1 human (sc-37139, Santa Cruz), siNQO1 mouse (sc-37140, Santa Cruz) and siRNA control (sc-37007, Santa Cruz) were used

(13) Nrf2-mediated neuroprotection against oxygen-glucose deprivation/reperfusion injury by emodin via AMPK-dependent inhibition of GSK-3βThe Journal of pharmacy and pharmacologyApril 1, 2018Park SY, Choi YW, Park G.

(14) A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1OncoTargets and therapyJanuary 1, 2018Zhao XZ, Wu XH.

(15) NQO1 Is Regulated by PTEN in Glioblastoma, Mediating Cell Proliferation and Oxidative StressOxidative medicine and cellular longevityJanuary 1, 2018Luo S, Lei K, Xiang D, Ye K.intensity was monitored at EX/EM of 490/520 nm. 2.6. Transfection of siRNA and Plasmids. The NQO1-siRNA (#sc-37139), PTEN-siRNA (#sc-29459), and nontargeting siRNA (#sc-37007) as a control were purchased from Santa Cruz Biotechnology

(16) Overexpression of NAD(P)H: Quinone Oxidoreductase 1 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induced Apoptosis by Activating AMPK/PGC-1α PathwayDNA and cell biologyApril 1, 2017Zhang X, Han K, Yuan DH, Meng CY.

(17) Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLCMolecular cancer research : MCRJanuary 1, 2016Madajewski B, Boatman MA, Chakrabarti G, Boothman DA, Bey EA.or non-silencing control vector as described previously (7). Human shRNA-NQO1 lentiviral particles (sc-37139) and controls were purchased from Santa Cruz Biotechnology. Stable shNQO1 lentiviral knockdown (A549-shNQO1-B)

(18) Cucurbitacins attenuate microglial activation and protect from neuroinflammatory injury through Nrf2/ARE activation and STAT/NF-κB inhibitionNeuroscience lettersNovember 16, 2015Park SY, Kim YH, Park G.

(19) miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivoOncotargetMarch 20, 2015Yeh LY, Liu CJ, Wong YK, Chang C, Lin SC, Chang KW.

(20) β-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cellsCell death & diseaseMay 15, 2014Park EJ, Min KJ, Lee TJ, Yoo YH, Kim YS, Kwon TK.