Nox4 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNox4 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-41586
Quantity10 µM
Gene NameNADPH oxidase 4
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene NameNADPH oxidase 4
NCBI Gene AliasesKOX, KOX-1, RENOX

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Diosgenin Reduces Acute Kidney Injury and Ameliorates the Progression to Chronic Kidney Disease by Modifying the NOX4/p65 Signaling PathwaysJournal of agricultural and food chemistryAugust 7, 2024Chiang CH, Lan TY, Hsieh JH, Lin SC, Chen JW, Chang TT.proteins. Transfection of NOX4 siRNA HK2 cells were transfected with the siRNA of NOX4 (Santa Cruz, sc-41586, Dallas, TX, USA) by using an oligofectamine (Thermo Fisher Scientific, 12252011, Waltham, USA) reagent

(2) The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin IIAntioxidants (Basel)April 22, 2024Michael Adu-Gyamfi, Claudia Goettsch, Julian Kamhieh-Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunssen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, et al.vectors. Transient transfections of HMECs with siRNAs targeting NOX1 (sc-43939), NOX2 (sc-35503), NOX4 (sc-41586), OCT1 (sc-42552), or a scrambled siRNA control (sc-37007) (all from Santa Cruz Biotechnology, Heidelberg,

(3) Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidationCell reportsNovember 28, 2023Kang DH, Kim Y, Min S, Lee SY, Chung KY, Baek IJ, Kwon K, Jo H, Kang SW.NOX2,Santa Cruz,Cat# sc-35503 5′- GAA CAG GCU AAG GAU ACU A −3′,, siRNA sequence for NOX4,Santa Cruz,Cat# sc-41586 5′- AAC GAA GGG GUU AAA CAC CUC −3′,, siRNA sequence for eNOS,Dharmacon,https://doi.org/10.1074/jbc.M112.436022. 5′-GGU

(4) Effects of SIDT2 on the miR-25/NOX4/HuR axis and SIRT3 mRNA stability lead to ROS-mediated TNF-α expression in hydroquinone-treated leukemia cellsCell biology and toxicologyOctober 1, 2023Wang LJ, Lee YC, Chiou JT, Chen YJ, Chang LS.

(5) Targeting ER Stress with Saikosaponin A to Overcome Resistance under Radiation in Gastric Cancer CellsInternational journal of molecular sciencesMarch 16, 2023Kim TW.nmol/mL, Santa Cruz) against GRP78 (Santa Cruz; sc-29338), PERK (Santa Cruz; sc-36213), Nox4 (Santa Cruz; sc-41586), and CHOP (Bioneer; 1649-1) and shRNAs against PERK (Santa Cruz; sc-36213-SH) for 24 h using Lipofectamine

(6) Nodakenin Induces ROS-Dependent Apoptotic Cell Death and ER Stress in Radioresistant Breast CancerAntioxidants (Basel, Switzerland)February 15, 2023Kim TW.

(7) BCL2 inhibitor ABT-199 and BCL2L1 inhibitor WEHI-539 coordinately promote NOXA-mediated degradation of MCL1 in human leukemia cellsChemico-biological interactionsJuly 1, 2022Chiou JT, Lee YC, Wang LJ, Chang LS.

(8) The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent mannerRedox biologyJune 1, 2022Tarafdar A, Wolska N, Krisp C, Schlüter H, Pula G.gene silencing with siRNA, HUVECs were transfected with NOX1 (#sc-43939), NOX2 (#sc-35503), NOX4 (#sc-41586), NOX5 (#sc-45486) or scrambled control (#sc-37007) siRNAs (Santa Cruz Biotechnology) as per manufacturer's

(9) CREB/Sp1-mediated MCL1 expression and NFκB-mediated ABCB1 expression modulate the cytotoxicity of daunorubicin in chronic myeloid leukemia cellsToxicology and applied pharmacologyJanuary 15, 2022Chiou JT, Huang CH, Wu TH, Wang LJ, Lee YC, Huang PW, Chang LS.

(10) Chlamydia trachomatis Requires Functional Host-Cell Mitochondria and NADPH Oxidase 4/p38MAPK Signaling for Growth in NormoxiaFrontiers in cellular and infection microbiologyJanuary 1, 2022Thapa J, Yoshiiri G, Ito K, Okubo T, Nakamura S, Furuta Y, Higashi H, Yamaguchi H.Cells Transient NOX4-knockdown HEp-2 cells were established by 24-h transfection of cells with NOX4 siRNA (sc-41586; Santa Cruz Bio). Non-targeting scramble RNA (sc-37007; Santa Cruz Bio) was used as a control. Transfection

(11) NOXA-mediated degradation of MCL1 and BCL2L1 causes apoptosis of daunorubicin-treated human acute myeloid leukemia cellsJournal of cellular physiologyNovember 1, 2021Chiou JT, Huang NC, Huang CH, Wang LJ, Lee YC, Shi YJ, Chang LS.

(12) Histone deacetylase 3 inhibition alleviates type 2 diabetes mellitus-induced endothelial dysfunction via Nrf2Cell communication and signaling : CCSMarch 18, 2021Huang S, Chen G, Sun J, Chen Y, Wang N, Dong Y, Shen E, Hu Z, Gong W, Jin L, et al.(si-Nrf2) (Santa Cruz Biotechnology, sc-37030), human Nox4 siRNA (si-Nox4) (Santa Cruz Biotechnology, sc-41586) or control scramble siRNA by Lipofectamine 3000 for 12 h in Opti-MEM. After the transfection, cells

(13) Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient MiceInternational journal of molecular sciencesFebruary 10, 2021Yabuuchi N, Hou H, Gunda N, Narita Y, Jono H, Saito H.Santa Cruz Biotechnology, Dallas, Texas, USA), XO (sc-41691, Santa Cruz Biotechnology, Dallas, Texas, USA), and NOX4 (sc-41586, Santa Cruz Biotechnology, Dallas, Texas, USA) siRNA (50 nM) using Lipofectamine RNAi MAX (Thermo Fisher

(14) Hyperglycemia Induces Myocardial Dysfunction via Epigenetic Regulation of JunDCirculation researchOctober 23, 2020Hussain S, Khan AW, Akhmedov A, Suades R, Costantino S, Paneni F, Caidahl K, Mohammed SA, Hage C, Gkolfos C, et al.

(15) Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunctionRedox biologySeptember 1, 2020Jiang J, Huang K, Xu S, Garcia JGN, Wang C, Cai H.seeded into six-well plates, grown to 95% confluence, and transfected with human NOX4 siRNA (Cat#: SC-41586, Santa Cruz) or negative control siRNA (Cat#: SC-37007, Santa Cruz) using the transfection reagent Lipofectamine

(16) The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritisArthritis research & therapyMay 15, 2020Lee HR, Yoo SJ, Kim J, Yoo IS, Park CK, Kang SW.Scientific). siRNA transfection Specific siRNA targeting NOX4 was purchased from Santa Cruz Biotechnology (sc-41586). Cells were transfected with lipofectamine transfection reagent (Invitrogen) and the indicated siRNA

(17) NOX4 overexpression is a poor prognostic factor in patients undergoing curative esophagectomy for esophageal squamous cell carcinomaSurgeryMarch 1, 2020Chen YH, Lu HI, Lo CM, Hsiao CC, Li SH.

(18) Inhibition of vascular adventitial remodeling by netrin-1 in diabetic ratsThe Journal of endocrinologyMarch 1, 2020Wang HF, Yu QQ, Zheng RF, Xu M.netrin-1, UNC5b, and Nox4 were purchased from Santa Cruz (sc-270422), Sangon Biotech, and Santa Cruz (sc-41586), respectively. The targeting sequence was as follows: Netrin-1 (5′-AAGCUGGACGCAGCAUGAUGC-3′), Nox4

(19) SIRT3, PP2A and TTP protein stability in the presence of TNF-α on vincristine-induced apoptosis of leukaemia cellsJournal of cellular and molecular medicineFebruary 1, 2020Wang LJ, Chiou JT, Lee YC, Huang CH, Shi YJ, Chang LS.

(20) Silver Nanoparticle-Induced Apoptosis in ARPE-19 Cells Is Inhibited by Toxoplasma gondii Pre-Infection Through Suppression of NOX4-Dependent ROS GenerationInternational journal of nanomedicineJanuary 1, 2020Quan JH, Gao FF, Ismail HAHA, Yuk JM, Cha GH, Chu JQ, Lee YH.

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Nox4 siRNA (h)

Nox4 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Nox4 siRNA (h) from Santa Cruz Biotechnology, Inc.

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