PINK1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPINK1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-44598
Quantity10 µM
Gene NamePTEN induced putative kinase 1
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene NamePTEN induced kinase 1
NCBI Gene AliasesBRPK, PARK6

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Parkin Deficiency Impairs ER-Mitochondria Associations and calcium homeostasis via IP3R-Grp75-VDAC1 ComplexInternational Journal of Biological SciencesJanuary 1, 2026Nai-Jia Xue, Yi Liu, Zhi-Hao Lin, Wen-Hao Huang, Feng Zhang, Ran Zheng, Xiao-Li Si, Lu-Yan Gu, Yi Fan, Jia-Li Pu, et al.(Invitrogen). PINK1 knockdown was achieved by using siRNAs against PINK1 obtained from Santa Cruz (sc-44598). Briefly, siRNA and Lipofectamine RNAiMAX were each diluted in Opti-MEM, then combined and incubated

(2) DNA damage response regulator ATR licenses PINK1-mediated mitophagyNucleic Acids ResMarch 19, 2025Christian Marx, Xiaobing Qing, Yamin Gong, Joanna Kirkpatrick, Kanstantsin Siniuk, Galina V Beznoussenko, Gururaj Rao Kidiyoor, Murat Kirtay, Katrin Buder, Philipp Koch, et al.sc-37007, sc-44230, and sc-44231) and targeted siRNAs against ATR (siATR#1: sc-29763), PINK1 (siPINK1#1: sc-44598), TIM23 (sc-44155), TOM7 (sc-89537), and HSP90 (sc-35608) were purchased from Santa Cruz Biotechnologies,

(3) cRGD-Conjugated Bilirubin Nanoparticles Alleviate Dry Eye Disease Via Activating the PINK1-Mediated MitophagyInvestigative Ophthalmology & Visual ScienceNovember 26, 2024Yang Huang, Lijun Wang, Haiying Jin(14347-1-AP) were purchased from Proteintech Group, Inc. (Hubei, China). Pink1 small interfering RNA (siRNA; sc-44598) and scramble siRNA (sc-37007) were purchased from Santa Cruz Biotechnology, Inc. (Dallas, TX, USA). Preparation

(4) Elevated PINK1/Parkin-Dependent Mitophagy and Boosted Mitochondrial Function Mediate Protection of HepG2 Cells from Excess Palmitic Acid by HesperetinJournal of Agricultural and Food ChemistryJune 12, 2024Wan Li, Zhengnan Cai, Florian Schindler, Leila Afjehi-Sadat, Bianca Montsch, Petra Heffeter, Elke H. Heiss, Wolfram WeckwerthAfter 48 h of transfection, the cells were treated and processed, as described above. Pink1 siRNA (sc-44598) and control-siRNA (sc-37007) were obtained from Santa Cruz (Heidelberg, Germany). 2.13 Metabolomic

(5) PTEN-induced kinase 1 is associated with renal aging, via the cGAS-STING pathwayAging cellJuly 1, 2023Ha MH, Kim MS, An HJ, Sung MJ, Lee YH, Yang DH, Jung SH, Baek J, Choi Y, Taylor DM, et al.was performed according to the protocol described by Lipofectamine® RNAiMAX Reagent. The PINK1 siRNA (sc‐44598; Santa Cruz Biotechnology) and STING siRNA (sc‐92042; Santa Cruz Biotechnology) were dissolved in siRNA

(6) Sesamin Alleviates Asthma Airway Inflammation by Regulating Mitophagy and Mitochondrial ApoptosisJournal of agricultural and food chemistryApril 27, 2022Bai Q, Wang Z, Piao Y, Zhou X, Piao Q, Jiang J, Liu H, Piao H, Li L, Song Y, et al.

(7) Ultrafine black carbon caused mitochondrial oxidative stress, mitochondrial dysfunction and mitophagy in SH-SY5Y cellsThe Science of the total environmentMarch 20, 2022Shang Y, Xue W, Kong J, Chen Y, Qiu X, An X, Li Y, Wang H, An J.

(8) Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagyActa pharmaceutica Sinica. BFebruary 1, 2022Sun X, Shu Y, Ye G, Wu C, Xu M, Gao R, Huang D, Zhang J.(siRNA) and plasmids transient transfection The siRNAs targeting PINK1 (Santa Cruz Biotechnology, sc-44598), ULK1 (GenePharma, Shanghai), ACAT1 (Santa Cruz Biotechnology, sc-96390), HDAC1 (GenePharma, Shanghai),

(9) Activation of UQCRC2-dependent mitophagy by tetramethylpyrazine inhibits MLKL-mediated hepatocyte necroptosis in alcoholic liver diseaseFree radical biology & medicineFebruary 1, 2022Zhou Y, Wu R, Wang X, Jiang Y, Xu W, Shao Y, Yue C, Shi W, Jin H, Ge T, et al.

(10) SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy ImpairmentFrontiers in microbiologyJanuary 1, 2021Shang C, Liu Z, Zhu Y, Lu J, Ge C, Zhang C, Li N, Jin N, Li Y, Tian M, et al.Transfection The control siRNA (sc-37007), siRNA against Tom20 (sc-36691) and siRNA against Pink1 (sc-44598) were purchased from Santa Cruz Biotechnology (California, United States). Twenty-four hours after seeding,

(11) Exosomes Regulate Interclonal Communication on Osteogenic Differentiation Among Heterogeneous Osteogenic Single-Cell Clones Through PINK1/Parkin-Mediated MitophagyFrontiers in cell and developmental biologyJanuary 1, 2021Fei D, Xia Y, Zhai Q, Wang Y, Zhou F, Zhao W, He X, Wang Q, Jin Y, Li B.SCCs using Lipo2000 (Invitrogen). For siRNA experiments, SCCs were transfected with 50 nM PINK1 siRNA (sc-44598) or scrambled siRNA (sc-37007) (both from Santa Cruz Biotechnology, Santa Cruz, CA, United States). After

(12) Cyanidin-3-O-glucoside improves non-alcoholic fatty liver disease by promoting PINK1-mediated mitophagy in miceBritish journal of pharmacologyAugust 1, 2020Li X, Shi Z, Zhu Y, Shen T, Wang H, Shui G, Loor JJ, Fang Z, Chen M, Wang X, et al.

(13) Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion InjuryFrontiers in pharmacologyJanuary 1, 2020Xiang Q, Wu M, Zhang L, Fu W, Yang J, Zhang B, Zheng Z, Zhang H, Lao Y, Xu H.the manufacturer’s speciﬁcations. Cells were then treated with GeX1 and McX. PINK1 siRNA (Santa Cruz Biotechnology, sc44598), Parkin siRNA (rat) and negative control siRNA were purchased from GenePharma. The sequences of PINK1

(14) Involvement of phosphatase and tensin homolog-induced putative kinase 1-Parkin-mediated mitophagy in septic acute kidney injuryChinese medical journalOctober 5, 2019Dai XG, Xu W, Li T, Lu JY, Yang Y, Li Q, Zeng ZH, Ai YH.

(15) PINK1 protects against oxidative stress induced senescence of human nucleus pulposus cells via regulating mitophagyBiochemical and biophysical research communicationsOctober 2, 2018Wang Y, Shen J, Chen Y, Liu H, Zhou H, Bai Z, Hu Z, Guo X.

(16) Artesunate-induced mitophagy alters cellular redox statusRedox biologyOctober 1, 2018Zhang J, Sun X, Wang L, Wong YK, Lee YM, Zhou C, Wu G, Zhao T, Yang L, Lu L, et al.(siRNA) and transient transfection The scrambled RNAi oligonucleotides and siRNAs targeting PINK1 (sc-44598, Santa Cruz Biotechnology) were transfected into HeLa cells using the DharmaFECT 4 Transfection Reagent

(17) High Expression of the Mitophagy-Related Protein Pink1 is Associated with a Poor Response to Chemotherapy and a Poor Prognosis for Patients Treated with Neoadjuvant Chemotherapy for Esophageal Squamous Cell CarcinomaAnnals of surgical oncologyDecember 1, 2017Yamashita K, Miyata H, Makino T, Masuike Y, Furukawa H, Tanaka K, Miyazaki Y, Takahashi T, Kurokawa Y, Yamasaki M, et al.

(18) Pink1/Parkin-mediated mitophagy play a protective role in cisplatin induced renal tubular epithelial cells injuryExperimental cell researchJanuary 15, 2017Zhao C, Chen Z, Xu X, An X, Duan S, Huang Z, Zhang C, Wu L, Zhang B, Zhang A, et al.

(19) Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1-Parkin PathwayAntioxidants & redox signalingMarch 20, 2016Ma S, Zhang X, Zheng L, Li Z, Zhao X, Lai W, Shen H, Lv J, Yang G, Wang Q, et al.

(20) BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal SurvivalThe Journal of biological chemistryDecember 18, 2015Qu D, Hage A, Don-Carolis K, Huang E, Joselin A, Safarpour F, Marcogliese PC, Rousseaux MW, Hewitt SJ, Huang T, et al.

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PINK1 siRNA (h)

PINK1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PINK1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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