MDM2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMDM2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29394
Gene NameMdm2 p53 binding protein homolog (mouse)
Quantity10 µM
Specieshuman
NCBI Full Gene NameMDM2 proto-oncogene
NCBI Gene AliasesACTFS, HDMX, LSKB, hdm2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Tailorable bimetallic nanozyme mitigates intervertebral disc degeneration by inhibiting oxidative stress and inflammageingTheranosticsJune 9, 2025Anran Zhang, Haiyang Gao, Xianglong Chen, Pengzhi Shi, Zhangrong Cheng, Yuhang Chen, Wang Wu, Wenbo Wu, Cao Yang, Yukun Zhangcontrol siRNA (Santa Cruz Biotechnology, sc-37007); MDM2-targeting siRNA (Santa Cruz Biotechnology, sc-29394). Cells were seeded 12 hours prior to transfection, achieving 30-50% confluence by Day 0. Reverse transfection

(2) FGF12 Positively Regulates Keratinocyte Proliferation by Stabilizing MDM2 and Inhibiting p53 Activity in PsoriasisAdvanced ScienceOctober 1, 2024Nan Wang, Xiejun Xu, Fangqian Guan, Yifan Lin, Yizhou Ye, Jie Zhou, Jianjun Feng, Sihang Li, Junbo Ye, Zhouhao Tang, et al.(Santa Cruz Biotechnology, sc‐39466), p53 siRNA (Santa Cruz Biotechnology, sc‐29435), MDM2 siRNA (Santa Cruz Biotechnology, sc‐29394), and β‐Trcp siRNA (Santa Cruz Biotechnology, sc‐37178) were utilized. The cells were seeded 12 h prior

(3) Gentian violet induces apoptosis and ferroptosis via modulating p53 and MDM2 in hepatocellular carcinomaAmerican journal of cancer researchJanuary 1, 2022Chen J, Zhao F, Yang H, Wen J, Tang Y, Wan F, Zhang X, Wu J.

(4) p21(WAF1/CIP1) promotes p53 protein degradation by facilitating p53-Wip1 and p53-Mdm2 interactionBiochemical and biophysical research communicationsMarch 5, 2021Lee J, Kim J, Kim EM, Kim U, Kang AR, Park JK, Um HD.

(5) Neddylation of PTEN regulates its nuclear import and promotes tumor developmentCell researchMarch 1, 2021Xie P, Peng Z, Chen Y, Li H, Du M, Tan Y, Zhang X, Lu Z, Cui CP, Liu CH, et al.

(6) Small Proline-Rich Protein 2B Facilitates Gastric Adenocarcinoma Proliferation via MDM2-p53/p21 Signaling PathwayOncoTargets and therapyJanuary 1, 2021Yao L, Yan J, Cheng F, Gan L, Huang Y, Zheng L, Fang N.

(7) TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2American journal of respiratory and critical care medicineNovember 1, 2020Fan Y, Gu X, Zhang J, Sinn K, Klepetko W, Wu N, Foris V, Solymosi P, Kwapiszewska G, Kuebler WM.

(8) Carcinogenic role of K-Ras-ERK1/2 signaling in bladder cancer via inhibition of H1.2 phosphorylation at T146Journal of cellular physiologyNovember 1, 2019Fan L, Wang Y, Wang W, Wei X.

(9) CP‑31398 attenuates endometrial cancer cell invasion, metastasis and resistance to apoptosis by downregulating MDM2 expressionInternational journal of oncologyMarch 1, 2019Liu L, Yang L, Chang H, Chen YN, Zhang F, Feng S, Peng J, Ren CC, Zhang XA.(Thermo Fisher Scientific, Waltham, MA, USA). The 100 pmol siRNA-MDM2 or oe-MDM2 and MDM2 NC sequences (sc-29394, purchased from Santa Cruz Biotechnology Co., Ltd., Shanghai, China) were diluted using 250 µl serum-free

(10) MALAT1 Activates the P53 Signaling Pathway by Regulating MDM2 to Promote Ischemic StrokeCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Zhang T, Wang H, Li Q, Fu J, Huang J, Zhao Y.

(11) miR-5003-3p promotes epithelial-mesenchymal transition in breast cancer cells through Snail stabilization and direct targeting of E-cadherinJournal of molecular cell biologyOctober 1, 2016Kwak SY, Yoo JO, An HJ, Bae IH, Park MJ, Kim J, Han YH.

(12) Enhancing radiosensitivity of TE1, TE8, and TE 11 esophageal squamous carcinoma cell lines by Hdm2-siRNA targeted gene therapy in vitroBioImpactsJune 28, 2016Jalil Pirayesh Islamian, Mohsen Mohammadi, Behzad Baradaran, Alireza Farajollahi, Seyed Mahmoud Reza Aghamiri, Mohammad Asghari Jafarabadi, Haadi Karami, Amir Monfaredan, Dariuosh Shanehbandimembrane and probed with hdm-2 polyclonal antibody (Santa Cruz Biotechnology, Santa Cruz, CA, Code No. sc-29394). Membranes were processed by enhanced chemiluminescence method (Roche, Germany). Protein bands were

(13) Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3OncotargetMay 31, 2016Yang P, Chen W, Li X, Eilers G, He Q, Liu L, Wu Y, Wu Y, Yu W, Fletcher JA, et al.reagents Monoclonal antibodies to p53, cyclin A, cyclin D1, cyclin E, ubiquitin, preimmune serum, and MDM2 siRNA (sc-29394) were from Santa Cruz Biotechnology (Santa Cruz, CA). Monoclonal antibody to RB and polyclonal antibody

(14) Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cellsOncotargetNovember 3, 2015Slabáková E, Kharaishvili G, Smějová M, Pernicová Z, Suchánková T, Remšík J, Lerch S, Straková N, Bouchal J, Král M, et al.

(15) A MDM2-dependent positive-feedback loop is involved in inhibition of miR-375 and miR-106b induced by Helicobacter pylori lipopolysaccharideInternational journal of cancerMay 1, 2015Ye F, Tang C, Shi W, Qian J, Xiao S, Gu M, Dang Y, Liu J, Chen Y, Shi R, et al.

(16) XI-011 enhances cisplatin-induced apoptosis by functional restoration of p53 in head and neck cancerApoptosis : an international journal on programmed cell deathNovember 1, 2014Roh JL, Park JY, Kim EH.

(17) Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in miceGastroenterologyOctober 1, 2014Wang W, Qin JJ, Voruganti S, Wang MH, Sharma H, Patil S, Zhou J, Wang H, Mukhopadhyay D, Buolamwini JK, et al.

(18) Inhibition of epithelial to mesenchymal transition by E-cadherin up-regulation via repression of slug transcription and inhibition of E-cadherin degradation: dual role of scaffold/matrix attachment region-binding protein 1 (SMAR1) in breast cancer cellsThe Journal of biological chemistrySeptember 12, 2014Adhikary A, Chakraborty S, Mazumdar M, Ghosh S, Mukherjee S, Manna A, Mohanty S, Nakka KK, Joshi S, De A, et al.

(19) HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulatorThe FEBS journalJuly 1, 2014Bhattacharya S, Ghosh MK.

(20) TRIAD1 is negatively regulated by the MDM2 E3 ligaseOncology reportsNovember 1, 2012Bae S, Jung JH, An IS, Kim OY, Lee MJ, Lee JH, Park IC, Lee SJ, An S.

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MDM2 siRNA (h)

MDM2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MDM2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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