GCN5 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemGCN5 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-37946
Gene NameK(lysine) acetyltransferase 2A
Quantity10 µM
Specieshuman
NCBI Full Gene Namelysine acetyltransferase 2A
NCBI Gene AliasesGCN5, GCN5L2, PCAF-b, hGCN5
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Epigenetic control of SOX9 gene by the histone acetyltransferase P300 in human Sertoli cellsHeliyonJune 30, 2024Daniel González, María José Peña, Camila Bernal, Mary García-Acero, Maria Carolina Manotas, Fernando Suarez-Obando, Adriana Rojastransfected with 50 μM siRNA oligonucleotides targeting P300 (sc-2943, Santa Cruz Biotechnology), GCN5 (sc-37946, Santa Cruz Biotechnology), and WDR5 (sc-61798, Santa Cruz Biotechnology). A non-targeting 20–25 nt

(2) α-Synuclein upregulates bim-mediated apoptosis by negatively regulating endogenous GCN5AgingOctober 27, 2022Azam S, Kim IS, Choi DK.NIS-Elements BR-2.01.00 software (which came with the instrument). RNA interference siRNA of GCN5 (#sc-37946; Santa Cruz Biotechnology) was used. The interference efficiency was detected by comparing siRNAs with

(3) Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylationAutophagyOctober 1, 2020Ouyang C, Mu J, Lu Q, Li J, Zhu H, Wang Q, Zou MH, Xie Z.

(4) Decreased MORF leads to prolonged endoplasmic reticulum stress in periodontitis-associated chronic inflammationCell death and differentiationNovember 1, 2016Xue P, Li B, An Y, Sun J, He X, Hou R, Dong G, Fei D, Jin F, Wang Q, et al.

(5) Nicotinamide adenine dinucleotide (NAD) may affect DNA methyltransferase 1 through regulation of BRCA1 in ovarian cancerAmerican journal of cancer researchJanuary 1, 2015Fang YY, Bi FF, Zhou YM, Sun WP, Li CY, Liu Q, Zhao Y, Li D.

(6) Stress-induced cleavage of Myc promotes cancer cell survivalGenes & developmentApril 1, 2014Conacci-Sorrell M, Ngouenet C, Anderson S, Brabletz T, Eisenman RN.

(7) Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: a novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylationMolecular cancerFebruary 6, 2014Li D, Bi FF, Cao JM, Cao C, Liu B, Yang Q.

(8) Poly (ADP-ribose) polymerase 1 transcriptional regulation: a novel crosstalk between histone modification H3K9ac and ETS1 motif hypomethylation in BRCA1-mutated ovarian cancerOncotargetJanuary 15, 2014Li D, Bi FF, Cao JM, Cao C, Li CY, Liu B, Yang Q.

(9) Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongationNucleic acids researchJuly 1, 2013Bertucci PY, Nacht AS, Alló M, Rocha-Viegas L, Ballaré C, Soronellas D, Castellano G, Zaurin R, Kornblihtt AR, Beato M, et al.over time zero. Primers sequences are available on request. RNA interference experiments siRNA GCN5 (sc-37946) and siRNA CBP (sc-29244) from Santa Cruz Biotechnology were transfected into the T47D cells using Lipofectamine

(10) USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathwayCell biochemistry and biophysicsJanuary 1, 2012Liu YL, Jiang SX, Yang YM, Xu H, Liu JL, Wang XS.

(11) GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damageNucleic acids researchMarch 1, 2011Guo R, Chen J, Mitchell DL, Johnson DG.5170 CCUGAUGAAUAUCUGUACU; strand 5171 GAGUCUGUGUGGUGUGUAU) and human GCN5-coding region (GCN5 siRNA sc37946: duplex 1 strand CCAAGCAGGUCUAUUUCUA; duplex 2 strand GGAAAUGCAUCCUGCAGAU; duplex 3 strand GAGGCCUCAUUGACAAGUA)

(12) Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansionMolecular and cellular biologyDecember 1, 2010Chen J, Luo Q, Yuan Y, Huang X, Cai W, Li C, Wei T, Zhang L, Yang M, Liu Q, et al.RNA (siRNA) duplexes of Pygo2 (sc-76303), MLL2 (sc75796), Ash2L (sc-43556), RbBP5 (sc-76373), GCN5 (sc-37946), TRRAP (sc-36746), and ADA3 (sc-78466) and a negative-control scrambled sequence (sc-37007) were purchased

(13) A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repairThe EMBO journalApril 21, 2010Lee HS, Park JH, Kim SJ, Kwon SJ, Kwon J.Cotransfection with BRG1 and hBrm siRNA was performed as described earlier (Park et al, 2006). siRNAs for GCN5 (sc-37946) and PCAF(sc-36198) were purchased from Santa Cruz. It is noted that transfection with BRG1 siRNA leads

(14) TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcriptionProceedings of the National Academy of Sciences of the United States of AmericaSeptember 18, 2007Kenneth NS, Ramsbottom BA, Gomez-Roman N, Marshall L, Cole PA, White RJ.

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GCN5 siRNA (h)

GCN5 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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GCN5 siRNA (h) from Santa Cruz Biotechnology, Inc.

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