PERK siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPERK siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36214
Gene Nameeukaryotic translation initiation factor 2-alpha kinase 3
Quantity10 µM
Speciesmouse
NCBI Full Gene Nameeukaryotic translation initiation factor 2 alpha kinase 3
NCBI Gene AliasesPek, Perk
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The TWEAK/Fn14 signaling mediates skeletal muscle wasting during cancer cachexiaiScienceJuly 18, 2025Meiricris Tomaz da Silva, Anirban Roy, Anh Tuan Vuong, Aniket S. Joshi, Cristeena Josphien, Meghana V. Trivedi, Sajedah M. Hindi, Vihang A. Narkar, Ashok Kumar,Santa Cruz Biotechnology,sc-37007 Fn14 siRNA (m),Santa Cruz Biotechnology,sc-145209 PERK siRNA (m),Santa Cruz Biotechnology,Sc-36214 ,, Software and algorithms,Software and algorithms,Software and algorithms ,, ImageJ software,NIH,N/A NIS Elements

(2) Macrophage Reprogramming via the Modulation of Unfolded Protein Response with siRNA-Loaded Magnetic Nanoparticles in a TAM-like Experimental ModelPharmaceuticsJune 12, 2023D'Urso A, Oltolina F, Borsotti C, Prat M, Colangelo D, Follenzi A.(Bioscience). 2.7. Gene Silencing Efficiency of PERK Protein via PDA-MNPs/siPERK siPERK duplex (Cat. sc-36214, Santa Cruz Biotechnology) was purchased as a solution of three specific siRNAs. PEMs seeded in a 6-well

(3) Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn miceNature communicationsJuly 27, 2022Weber AA, Yang X, Mennillo E, Ding J, Watrous JD, Jain M, Chen S, Karin M, Tukey RH.After 72 h, hepatocytes were collected for Q-RT-PCR and WB. siRNA specific for mouse PERK (Santa Cruz, sc-36214) and control (Santa Cruz, sc-37007) were purchased at Santa Cruz Biotechnology. Four hours after primary

(4) PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleenThe Journal of experimental medicineApril 4, 2022Liu M, Wu C, Luo S, Hua Q, Chen HT, Weng Y, Xu J, Lin H, Wang L, Li J, et al.ATF4 siRNAs (Assay ID: MSS202232, MSS202233, MSS202234; Thermo Fisher Scientific), or PERK siRNAs (sc-36214; Santa Cruz) or without transfection (negative control). Electrophoretic transfection was performed

(5) PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathwayRedox biologyApril 1, 2022Lee DH, Park JS, Lee YS, Bae SH.and 50%–70% humidity. To the depletion of PERK in mice, PERK siRNA (20 nM, Santa Cruz Biotechnology; sc-36214) was injected through the tail vein along with the Invivofectamine 3.0 reagent (Thermo Fisher Scientific,

(6) Schweinfurthin induces ICD without ER stress and caspase activationOncoimmunologyJanuary 1, 2022Zhang R, Neighbors JD, Schell TD, Hohl RJ.

(7) Up-regulation of thioredoxin system by puerarin inhibits lipid uptake in macrophagesFree radical biology & medicineJanuary 1, 2021Li W, Xu X, Dong D, Lei T, Ou H.

(8) STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stressBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieMay 1, 2020Zhang Y, Chen W, Wang Y.

(9) Aberrant ER Stress Induced Neuronal-IFNβ Elicits White Matter Injury Due to Microglial Activation and T-Cell Infiltration after TBIThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 8, 2020Sen T, Saha P, Gupta R, Foley LM, Jiang T, Abakumova OS, Hitchens TK, Sen N.

(10) FGF21 induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathwayFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMay 1, 2018Joe Y, Kim S, Kim HJ, Park J, Chen Y, Park HJ, Jekal SJ, Ryter SW, Kim UH, Chung HT.interfering RNA transfection Small interfering RNAs (siRNAs) against mouse Fgf21 (sc-39485) and Perk (sc-36214) were purchased from Santa Cruz Biotechnology, and negative control siRNA (scRNA; AM4611) was purchased

(11) Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagyNature communicationsNovember 24, 2017Li W, Zhu J, Dou J, She H, Tao K, Xu H, Yang Q, Mao Z.(cat#sc-37007), IRE1 (cat#sc-40706), MKK3 (cat#sc-35908), MKK4 (cat#sc-35910), MKK6 (cat#sc-35914), and PERK (cat#sc-36214) were purchased from Santa Cruz. Cell culture SN4741 cells (a gift from Dr. Jin H. Son, Cornell University

(12) Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathwayFree radical biology & medicineSeptember 1, 2017Kim HJ, Joe Y, Kim SK, Park SU, Park J, Chen Y, Kim J, Ryu J, Cho GJ, Surh YJ, et al.

(13) Tunicamycin aggravates endoplasmic reticulum stress and airway inflammation via PERK-ATF4-CHOP signaling in a murine model of neutrophilic asthmaThe Journal of asthma : official journal of the Association for the Care of AsthmaMarch 1, 2017Guo Q, Li H, Liu J, Xu L, Yang L, Sun Z, Zhou B.

(14) Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent mannerCell cycle (Georgetown, Tex.)January 1, 2015Li H, Zhou B, Liu J, Li F, Li Y, Kang X, Sun H, Wu S.

(15) Involvement of the osteoinductive factors, Tmem119 and BMP-2, and the ER stress response PERK-eIF2α-ATF4 pathway in the commitment of myoblastic into osteoblastic cellsCalcified tissue internationalApril 1, 2014Tanaka K, Kaji H, Yamaguchi T, Kanazawa I, Canaff L, Hendy GN, Sugimoto T.

(16) Advanced glycation end products suppress osteoblastic differentiation of stromal cells by activating endoplasmic reticulum stressBiochemical and biophysical research communicationsAugust 30, 2013Tanaka K, Yamaguchi T, Kaji H, Kanazawa I, Sugimoto T.

(17) Pharmacological modulation of the retinal unfolded protein response in Bardet-Biedl syndrome reduces apoptosis and preserves light detection abilityThe Journal of biological chemistryOctober 26, 2012Mockel A, Obringer C, Hakvoort TB, Seeliger M, Lamers WH, Stoetzel C, Dollfus H, Marion V.

(18) Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent mannerPloS oneJanuary 1, 2012Yang Y, Li XJ, Chen Z, Zhu XX, Wang J, Zhang LB, Qiang L, Ma YJ, Li ZY, Guo QL, et al.nuclear. Small interfering RNA (siRNA) knockdown studies As described before [11], siRNA for PERK (sc-36214), DNA-PKcs (sc-35200) or p22 (sc-142330) was purchased from Santa Cruz Biotechnology (Santa Cruz, CA).

(19) Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cellsOncogeneJune 3, 2010Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B.

(20) Mechanical stimulation suppresses phosphorylation of eIF2alpha and PERK-mediated responses to stress to the endoplasmic reticulumFEBS lettersFebruary 19, 2010Hirasawa H, Jiang C, Zhang P, Yang FC, Yokota H.

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PERK siRNA (m)

PERK siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PERK siRNA (m) from Santa Cruz Biotechnology, Inc.

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