PAI-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPAI-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36179
Gene Nameserpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Quantity10 µM
Specieshuman
NCBI Full Gene Nameserpin family E member 1
NCBI Gene AliasesPAI, PAI-1, PAI1, PLANH1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) G Protein-coupled Estrogen Receptor 1 (GPER1) Regulates Expression of SERPINE1/PAI-1 and Inhibits Tumorigenic Potential of Cervical Squamous Cell Carcinoma Cells In VitroCancer Genomics - ProteomicsJanuary 3, 2025LINEA RÖRIG, SOPHIA RUCKRIEGL, JULIA GALLWAS, CARSTEN GRÜNDKERMeanwhile, the transfection mix for a 6-well plate, consisting of 500 μl OptiMEM, 3 μl SERPINE1 siRNA (sc-36179, Santa Cruz Biotechnology, Dallas, TX, USA) or control siRNA (sc-37007, Santa Cruz Biotechnology) and

(2) Suppressing Expression of SERPINE1/PAI1 Through Activation of GPER1 Reduces Progression of Vulvar CarcinomaCancer Genomics - ProteomicsNovember 3, 2024TAMMY DOELKER, JULIA GALLWAS, CARSTEN GRÜNDKERfor 6 h in a transfection mix, consisting of 1 ml of OptiMEM mixed well with 4 μl of diluted siRNA (sc-36179) targeting the SERPINE1/PAI1 gene or siControl (sc-37007) and 4 μl of siRNA transfection reagent (sc-29528,

(3) PAI-1 Regulation of p53 Expression and Senescence in Type II Alveolar Epithelial CellsCellsAugust 5, 2023Rana T, Jiang C, Banerjee S, Yi N, Zmijewski JW, Liu G, Liu RM.containing 10% FBS and antibiotics. The cells were transfected with non-target siRNA or PAI-1 siRNA (SC36179; Santa Cruz, Dallas, TX, USA) for 24 h and then treated with bleomycin (5 mU/mL, 203401; Calbiochem,

(4) Aging, Plasminogen Activator Inhibitor 1, Brain Cell Senescence, and Alzheimer's DiseaseAging and diseaseApril 1, 2023Jiang CS, Rana T, Jin LW, Farr SA, Morley JE, Qin H, Liu G, Liu RM.Carlsbad, CA USA), were transfected with non-targeted (NT) siRNA or PAI-1 siRNA (Santa Cruz, SC-37007 and SC-36179) for 24 hours and then treated with 200 µM H2O2 in serum-free medium for 2 days. Alternatively, the

(5) CO-Induced TTP Activation Alleviates Cellular Senescence and Age-Dependent Hepatic Steatosis via Downregulation of PAI-1Aging and diseaseApril 1, 2023Park J, Chen Y, Kim J, Hwang E, Park GH, Yang CH, Ryter SW, Park JW, Chung HT, Joe Y.

(6) PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activityScientific reportsJuly 16, 2022Furuya H, Sasaki Y, Chen R, Peres R, Hokutan K, Murakami K, Kim N, Chan OTM, Pagano I, Dyrskjøt L, et al.transfection RT112 and UM-UC-3 cells were transfected with a pool of 3 synthesized commercial PAI-1 (sc-36179, Santa Cruz Biotechnology) (RT112KD-PAI1 and UM-UC-3KD-PAI1) or pool of 3 scrambled negative control

(7) Gasotransmitter CO Attenuates Bleomycin-Induced Fibroblast Senescence via Induction of Stress Granule FormationOxidative medicine and cellular longevityJanuary 1, 2021Chen Y, Jiang F, Kong G, Yuan S, Cao Y, Zhang Q, Wang Q, Liu L.China). 2.3. Transfection of siRNAs Small interfering RNA (siRNA) against human PA I-1 (siPAI-1, sc-36179) and negative control siRNA (scRNA, sc-37007) were purchased from Santa Cruz Biotechnology, Inc. (Santa

(8) ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in gliomaCell death & diseaseOctober 7, 2019Xi X, Liu N, Wang Q, Chu Y, Yin Z, Ding Y, Lu Y.

(9) Rac-GTPase promotes fibrotic TGF-β1 signaling and chronic kidney disease via EGFR, p53, and Hippo/YAP/TAZ pathwaysFASEB journal : official publication of the Federation of American Societies for Experimental BiologySeptember 1, 2019Patel S, Tang J, Overstreet JM, Anorga S, Lian F, Arnouk A, Goldschmeding R, Higgins PJ, Samarakoon R.

(10) Di-(2-Ethylhexyl) Phthalate Promotes Release of Tissue Factor-Bearing Microparticles From Macrophages via the TGFβ1/Smad/PAI-1 Signaling PathwayThe American journal of the medical sciencesJune 1, 2019Yamaguchi R, Sakamoto A, Yamaguchi R, Haraguchi M, Narahara S, Sugiuchi H, Katoh T, Yamaguchi Y.

(11) TM5441, a plasminogen activator inhibitor-1 inhibitor, protects against high fat diet-induced non-alcoholic fatty liver diseaseOncotargetOctober 27, 2017Lee SM, Dorotea D, Jung I, Nakabayashi T, Miyata T, Ha H.confluence, cells were seeded in 6-well plates with medium containing 20 nM PAI-1 siRNA (Santa Cruz, sc36179) or non-target siRNA (Bioneer, Daejeon, Republic of Korea) and LipofectaminTM RNAiMAX (Invitrogen, Carlsbad,

(12) Reduced monocyte adhesion to aortae of diabetic plasminogen activator inhibitor-1 knockout miceInflammation research : official journal of the European Histamine Research Society ... [et al.]September 1, 2017Zhao R, Le K, Moghadasian MH, Shen GX.

(13) Regulatory effects of estetrol on the endothelial plasminogen pathway and endothelial cell migrationMaturitasMay 1, 2017Montt-Guevara MM, Palla G, Spina S, Bernacchi G, Cecchi E, Campelo AE, Shortrede JE, Canu A, Simoncini T.

(14) Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repairFASEB journal : official publication of the Federation of American Societies for Experimental BiologyOctober 1, 2016Samarakoon R, Rehfuss A, Khakoo NS, Falke LL, Dobberfuhl AD, Helo S, Overstreet JM, Goldschmeding R, Higgins PJ.

(15) Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 ExpressionClinical cancer research : an official journal of the American Association for Cancer ResearchJuly 15, 2016Yu XM, Jaskula-Sztul R, Georgen MR, Aburjania Z, Somnay YR, Leverson G, Sippel RS, Lloyd RV, Johnson BP, Chen H.

(16) Gemigliptin, a dipeptidyl peptidase-4 inhibitor, inhibits retinal pericyte injury in db/db mice and retinal neovascularization in mice with ischemic retinopathyBiochimica et biophysica actaDecember 1, 2015Jung E, Kim J, Kim CS, Kim SH, Cho MH.

(17) Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responsesThe Journal of pathologyAugust 1, 2015Samarakoon R, Helo S, Dobberfuhl AD, Khakoo NS, Falke L, Overstreet JM, Goldschmeding R, Higgins PJ.

(18) Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosisExperimental gerontologyJanuary 1, 2015Huang WT, Akhter H, Jiang C, MacEwen M, Ding Q, Antony V, Thannickal VJ, Liu RM.cells/well. After reaching 60–80% confluence, cells were transfected with either PAI-1 siRNA (Santa Cruz, sc36179) or Non-target siRNA (Santa Cruz, control siRNA-A) according to the protocol provided by the manufacturer.

(19) Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting CapacityPloS oneJanuary 1, 2015Tasev D, van Wijhe MH, Weijers EM, van Hinsbergh VW, Koolwijk P.and prepared according to manufacturer’s instructions. Pool of target-specific siRNAs against PAI-1 (sc-36179) was purchased from Santa Cruz Biotechnologies, USA. ON-TARGETplus Non-targeting Pool siRNA (cat.no.

(20) Involvement of fibrinolytic regulators in adhesion of monocytes to vascular endothelial cells induced by glycated LDL and to aorta from diabetic miceJournal of leukocyte biologyJune 1, 2014Zhao R, Ren S, Moghadasain MH, Rempel JD, Shen GX.

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PAI-1 siRNA (h)

PAI-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PAI-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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