Smad4 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSmad4 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29484
Gene NameSMAD family member 4
Quantity10 µM
Specieshuman
NCBI Full Gene NameSMAD family member 4
NCBI Gene AliasesDPC4, JIP, MADH4, MYHRS
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) SMAD4 Expression in Renal Cell Carcinomas Correlates With a Stem-Cell Phenotype and Poor Clinical OutcomesFrontiers in oncologyJanuary 1, 2021Rasti A, Madjd Z, Saeednejad Zanjani L, Babashah S, Abolhasani M, Asgari M, Mehrazma M.regions of the tumor; tissue sections were then incubated overnight at 4°C with the anti-SMAD4 antibody (sc-29484, Santa Cruz Biotechnology) using a 1:100 dilution. After being washed 3 times in Tris-buffered saline

(2) TRIM28/TIF1β and Fli-1 negatively regulate peroxynitrite generation via DUOX2 to decrease the shedding of membrane-bound fractalkine in human macrophages after exposure to substance PCytokineOctober 1, 2020Yamaguchi R, Haraguchi M, Yamaguchi R, Sakamoto A, Narahara S, Sugiuchi H, Yamaguchi Y.

(3) AZD3759 induces apoptosis in hepatoma cells by activating a p53-SMAD4 positive feedback loopBiochemical and biophysical research communicationsFebruary 5, 2019Chao D, Pang L, Shi Y, Wang W, Liu K.

(4) SMAD4 Somatic Mutations in Head and Neck Carcinoma Are Associated With Tumor ProgressionFrontiers in oncologyJanuary 1, 2019Lin LH, Chang KW, Cheng HW, Liu CJ.

(5) TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascadeExperimental & molecular medicineDecember 6, 2018Han Z, Kang D, Joo Y, Lee J, Oh GH, Choi S, Ko S, Je S, Choi HJ, Song JJ.

(6) ESE‑1 suppresses the growth, invasion and migration of human NSCLC cells and tumor formation in vivoOncology reportsSeptember 1, 2018Lou Z, Lee BS, Ha T, Xu Y, Kim HJ, Kim CH, Lee SH.(cat. no. SC‑376055), VEGF (cat. no. SC‑507), Smad4 (cat. no. SC‑7966), and siRNA for Smad4 (cat. no. SC‑29484) were purchased from Santa Cruz Biotechnology (Dallas, TX, USA). Anti‑V5 (cat. no. 46‑0708) was purchased

(7) miR‑3147 serves as an oncomiR in vulvar squamous cell cancer via Smad4 suppressionMolecular medicine reportsMay 1, 2018Yang XH, Guo F.

(8) Downregulation of miR‑19a‑3p promotes invasion, migration and bone metastasis via activating TGF‑β signaling in prostate cancerOncology reportsJanuary 1, 2018Wa Q, Li L, Lin H, Peng X, Ren D, Huang Y, He P, Huang S.GeneChem (Shanghai, China). Anti-miR-19a-3p, small interfering RNA (siRNA) for SMAD2 (sc-37238) and SMAD4 (sc-29484) knockdown (50 nmol/l) were obtained from Santa Cruz (Dallas, TX, USA). The sequence of anti-miR-19a-3p

(9) Astragaloside IV synergizes with ferulic acid to suppress hepatic stellate cells activation in vitroFree radical researchFebruary 1, 2017Dong H, Guo H, Liang Y, Wang X, Niu Y.

(10) Estrogen Modulates Bone Morphogenetic Protein-Induced Sclerostin Expression Through the Wnt Signaling PathwayTissue engineering. Part AJuly 1, 2015Kim RY, Yang HJ, Song YM, Kim IS, Hwang SJ.

(11) Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathwaysCancer lettersMay 1, 2015Chatterjee A, Mukhopadhyay S, Tung K, Patel D, Foster DA.control scrambled siRNA (Dharmacon), siRNAs targeted against S6K (sc-36165), eIF4E (sc-35284), Smad4 (sc-29484) and Rb (sc-29468) (Santa Cruz Biotechnology) were purchased. Lipofectamine RNAiMax (Invitrogen, 56532)

(12) Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cellsBiochimica et biophysica actaMay 1, 2015Wünsche C, Koch A, Goldschmeding R, Schwalm S, Meyer Zu Heringdorf D, Huwiler A, Pfeilschifter J.

(13) SND1 Acts Downstream of TGFβ1 and Upstream of Smurf1 to Promote Breast Cancer MetastasisCancer researchApril 1, 2015Yu L, Liu X, Cui K, Di Y, Xin L, Sun X, Zhang W, Yang X, Wei M, Yao Z, et al.

(14) MEK inhibition prevents tumour-shed transforming growth factor-β-induced T-regulatory cell augmentation in tumour milieuImmunologyApril 1, 2015Hossain DM, Panda AK, Chakrabarty S, Bhattacharjee P, Kajal K, Mohanty S, Sarkar I, Sarkar DK, Kar SK, Sa G.

(15) Galangin suppresses HepG2 cell proliferation by activating the TGF-β receptor/Smad pathwayToxicologyDecember 4, 2014Wang Y, Wu J, Lin B, Li X, Zhang H, Ding H, Chen X, Lan L, Luo H.

(16) Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitroInternational journal of molecular medicineAugust 1, 2014Jin L, Zhao J, Jing W, Yan S, Wang X, Xiao C, Ma B.5′-UGAGAACUGAAUUCCAUGGGUU-3′, 5′-AACCCAUGGAAUUCAGUUCUCA-3′ and 5′-UUGUACUACACAAAAGUACUG-3′. Smad4 siRNA (Smad4 siRNA: sc-29484; control siRNA: sc-37007) was purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). When the

(17) Hepcidin is directly regulated by insulin and plays an important role in iron overload in streptozotocin-induced diabetic ratsDiabetesMay 1, 2014Wang H, Li H, Jiang X, Shi W, Shen Z, Li M.STAT3 silence, cells were transfected with SMAD4 and STAT3 small interfering RNA (siRNA) products (sc-29484 and sc-29493; Santa Cruz Biotechnology) that generally consist of pools of three to ﬁve target-speciﬁc

(18) BxPC3 pancreatic cancer cells express a truncated Smad4 protein upon PI3K and mTOR inhibitionOncology lettersApril 1, 2014Legendre O, Sookdeo A, Foster DA.

(19) Wnt/β-catenin signaling pathway may regulate the expression of angiogenic growth factors in hepatocellular carcinomaOncology lettersApril 1, 2014Qu B, Liu BR, DU YJ, Chen J, Cheng YQ, Xu W, Wang XH.

(20) Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transitionCell death & diseaseFebruary 6, 2014Chaudhry P, Fabi F, Singh M, Parent S, Leblanc V, Asselin E.