GR siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemGR siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35505
Gene Namenuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Quantity10 µM
Specieshuman
NCBI Full Gene Namenuclear receptor subfamily 3 group C member 1
NCBI Gene AliasesGCCR, GCR, GCRST, GR, GRL
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The Glucocorticoid Receptor Inhibits NRF2-Mediated Expression of SLC7A11Free Radical Biology and MedicineDecember 16, 2025Sarah E. Lacher, Jennifer Krznarich, Daniel C. Levings, Salil Saurav Pathak, Miles Pufall, Yi-Mei Yang, Matthew Slatterynegative control siRNA (siRNA-A, sc37007, Santa Cruz Biotechnology, Santa Cruz, CA) or GR (NR3C1) siRNA (sc35505, Santa Cruz Biotechnology, Santa Cruz, CA). Cells were transfected using Lipofectamine RNAiMAX Transfection Reagent

(2) A TBX2-driven signaling switch from androgen receptor to glucocorticoid receptor confers therapeutic resistance in prostate cancerOncogeneDecember 20, 2024Sayanika Dutta, Hamed Khedmatgozar, Girijesh Kumar Patel, Daniel Latour, Jonathan Welsh, Mainak Mustafi, Antonina Mitrofanova, Manisha Tripathi, Srinivas Nandanaconcentration. The si-RNA mediated knockdown of GR was performed using human si-GR construct (SCBT # sc35505) and control si-RNA (sc37007) was purchased from Santa Cruz Biotechnology (TX, USA). The si-RNA transfection

(3) Skin Anti-Inflammatory Potential with Reduced Side Effects of Novel Glucocorticoid Receptor AgonistsInternational journal of molecular sciencesDecember 23, 2023Flori E, Mosca S, Kovacs D, Briganti S, Ottaviani M, Mastrofrancesco A, Truglio M, Picardo M.Boster Biological Technology Co. (Pleasanton, CA, USA). Non-specific siRNA (sc-37007) and GR siRNA (sc-35505) were from Santa Cruz Biotechnology (Dallas, TX, USA). The Amaxa® human keratinocyte Nucleofector kit

(4) Alpha-1-antitrypsin binds to the glucocorticoid receptor with anti-inflammatory and anti-mycobacterial significance in macrophagesThe Journal of ImmunologyNovember 1, 2022Xiyuan Bai, An Bai, Michele Tomasicchio, James R. Hagman, Ashley M. Buckle, Arnav Gupta, Vineela Kadiyala, Shaun Bevers, Karina A. Serban, Kevin Kim, et al.Israel. Cy3 goat anti-rabbit IgG (H+L) A10520 was purchased from Life Technologies Inc. GRa-siRNA (sc-35505) was purchased from Santa Cruz Biotechnologies (Dallas, TX). Macrophage culture Human THP-1 cells

(5) Profound Effects of Dexamethasone on the Immunological State, Synthesis and Secretion Capacity of Human Testicular Peritubular CellsCellsOctober 9, 2022Stepanov YK, Speidel JD, Herrmann C, Schmid N, Behr R, Köhn FM, Stöckl JB, Pickl U, Trottmann M, Fröhlich T, et al.as previously described [34]. Transfection was achieved using predesigned 10 nmol/L GR-siRNA (GR, #sc-35505, Santa Cruz Biotechnology, Dallas, TX, USA) or non-template (NT) control siRNA (10 nmol/L) with Lipofectamine

(6) Glucocorticoids increase the risk of preterm premature rupture of membranes possibly by inducing ITGA8 gene expression in the amnionPlacentaOctober 1, 2022Okazaki Y, Taniguchi K, Miyamoto Y, Kinoshita S, Nakabayashi K, Kaneko K, Hamada H, Satoh T, Murashima A, Hata K.

(7) Aldosterone Suppresses Endothelial Mitochondria through Mineralocorticoid Receptor/Mitochondrial Reactive Oxygen Species PathwayBiomedicinesMay 12, 2022Peng SY, Tsai CH, Wu XM, Huang HH, Chen ZW, Lee BC, Chang YY, Pan CT, Wu VC, Chou CH, et al.dissolved in double-distilled water (ddH2O). 2.3. Small Interfering (si)RNA and Reagents GR siRNA (sc-35505), MR siRNA (sc-38836), and its scramble (Scr) control (sc-37007) were purchased from Santa Cruz Biotech

(8) Overexpression of glucocorticoid receptor promotes the poor progression and induces cisplatin resistance through p38 MAP kinase in cervical cancer patientsAmerican journal of cancer researchJanuary 1, 2022Han GH, Yun H, Kim J, Chung JY, Kim JH, Cho H.

(9) Glucocorticoid Receptor Regulates TNFSF11 Transcription by Binding to Glucocorticoid Responsive Element in TNFSF11 Proximal Promoter RegionInternational journal of molecular sciencesJanuary 21, 2021Lovšin N, Marc J.Sigma-Aldrich) were used for loading controls. 4.6. RNA Interference siRNAs for silencing of NR3C1 (sc-35505) and a negative control (sc-37007) were purchased from Santa Cruz Biotechnology, Dallas, TX, USA. Here,

(10) Description of a Novel Mechanism Possibly Explaining the Antiproliferative Properties of Glucocorticoids in Duchenne Muscular Dystrophy Fibroblasts Based on Glucocorticoid Receptor GR and NFAT5International journal of molecular sciencesDecember 3, 2020Herbelet S, De Paepe B, De Bleecker JL.influence of GC on NFAT5 was determined. GR silencing was performed as follows: 4 µL GR siRNA (h): sc-35505 (Santa Cruz Biotechnology,) was diluted in 2 mL serum free DMEM (=20 nM). The specificity of GR siRNA

(11) Antagonizing effect of icaritin on apoptosis and injury of hippocampal neurocytes induced by amyloid beta via GR/BDNF signaling pathwayJournal of receptor and signal transduction researchDecember 1, 2020Tang C, Liu X, Zhu H, Lu Q.

(12) Interleukin-6 plays a critical role in aldosterone-induced macrophage recruitment and infiltration in the myocardiumBiochimica et biophysica acta. Molecular basis of diseaseMarch 1, 2020Liao CW, Chou CH, Wu XM, Chen ZW, Chen YH, Chang YY, Wu VC, Rose-John S, Hung CS, Lin YH, et al.

(13) Glucocorticoid Receptor α Mediates Roflumilast's Ability to Restore Dexamethasone Sensitivity in COPDInternational journal of chronic obstructive pulmonary diseaseJanuary 1, 2020Reddy AT, Lakshmi SP, Banno A, Reddy RC.Sigma-Aldrich, St. Louis, MO, USA) and Roﬂ (15141; Cayman Chemical, Ann Arbor, MI, USA), GRα siRNA (SC35505; Santa Cruz Biotechnology, Santa Cruz, CA, USA) transfection, ELISA-based cytokine and chemokine measurement (DTA00D

(14) Role of glucocorticoid signaling in urothelial tumorigenesis: Inhibition by prednisone presumably through inducing glucocorticoid receptor transrepressionMolecular carcinogenesisDecember 1, 2019Ide H, Inoue S, Mizushima T, Kashiwagi E, Zheng Y, Miyamoto H.

(15) Upregulated long noncoding RNA LOC105375913 induces tubulointerstitial fibrosis in focal segmental glomerulosclerosisScientific reportsJanuary 24, 2019Han R, Hu S, Qin W, Shi J, Zeng C, Bao H, Liu Z.and added to cells. C/EBPβ siRNA (sc-44251), Elk-1 siRNA (sc-35290), ERα siRNA (sc-29305), GR siRNA (sc-35505), snail siRNA(sc-38398) and XBP-1s siRNA (sc-38627) were bought from Santa Cruz (Dallas, Texas, USA).

(16) Pseudopterosin Inhibits Proliferation and 3D Invasion in Triple-Negative Breast Cancer by Agonizing Glucocorticoid Receptor AlphaMolecules (Basel, Switzerland)August 10, 2018Sperlich J, Teusch N.determined using the software of IncuCyte® Zoom (Version 2016B). 4.3. Knockdown Studies GRα siRNA (siGRα) sc-35505 was purchased from Santa Cruz Biotechnology (Dallas, TX, USA). Silencer® Select Negative Control No. 2 siRNA

(17) IL-6 trans-signalling contributes to aldosterone-induced cardiac fibrosisCardiovascular researchApril 1, 2018Chou CH, Hung CS, Liao CW, Wei LH, Chen CW, Shun CT, Wen WF, Wan CH, Wu XM, Chang YY, et al.

(18) Combination of cationic dexamethasone derivative and STAT3 inhibitor (WP1066) for aggressive melanoma: a strategy for repurposing a phase I clinical trial drugMolecular and cellular biochemistryDecember 1, 2017Sau S, Mondal SK, Kashaw SK, Iyer AK, Banerjee R.

(19) The Marine Natural Product Pseudopterosin Blocks Cytokine Release of Triple-Negative Breast Cancer and Monocytic Leukemia Cells by Inhibiting NF-κB SignalingMarine drugsAugust 23, 2017Sperlich J, Kerr R, Teusch N.

(20) Prednisolone induces apoptosis in corneal epithelial cells through the intrinsic pathwayScientific reportsJune 23, 2017Ryu JS, Ko JH, Kim MK, Wee WR, Oh JY.at the concentration of 10−5 M. For GR knockdown, hCECs were transfected with siRNA for GR (Cat no. sc-35505, Santa Cruz Biotechnology, Santa Cruz, CA) or scrambled siRNA (Cat no. sc-37007, Santa Cruz Biotechnology)

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GR siRNA (h)

GR siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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GR siRNA (h) from Santa Cruz Biotechnology, Inc.

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