Cox-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCox-2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29279
Gene Nameprostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprostaglandin-endoperoxide synthase 2
NCBI Gene AliasesCOX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathwayStem cell research & therapyApril 24, 2023Luan X, Chen P, Li Y, Yuan X, Miao L, Zhang P, Cao Q, Song X, Di G.conducted. Transfection of hADSCs with small interfering RNA (siRNA) hADSCs were transfected by COX-2 siRNA (sc-29279, Santa Cruz Biotechnology, CA, USA) combined with Lipofectamine 2000 (Invitrogen, Carlsbad, CA, USA),

(2) LncRNA RMRP aggravates LPS-induced HK-2 cell injury and AKI mice kidney injury by upregulating COX2 protein via targeting ELAVL1International immunopharmacologyMarch 1, 2023Xia H, Shanshan X, Sumeng L, Fang X, Tao Z, Cheng C.

(3) COX-2 strengthens the effects of acid and bile salts on human esophageal cells and Barrett esophageal cellsBMC molecular and cell biologyApril 12, 2022Jiangang S, Nayoung K, Hongfang W, Junda L, Li C, Xuefeng B, Mingsong L.

(4) Surfactin attenuates particulate matter-induced COX-2-dependent PGE(2) production in human gingival fibroblasts by inhibiting TLR2 and TLR4/MyD88/NADPH oxidase/ROS/PI3K/Akt/NF-κB signaling pathwayJournal of periodontal researchDecember 1, 2021Vo TTT, Wee Y, Chen YL, Cheng HC, Tuan VP, Lee IT.

(5) Enhanced expression of cyclooxygenase-2 related multi-drug resistance gene in melanoma and osteosarcoma cell lines by TSG-6 secreted from canine adipose-derived mesenchymal stem/stromal cellsVeterinary medicine and scienceMay 1, 2021Yang SJ, An JH, Park SM, Lee JH, Chae HK, Lee KM, Song WJ, Youn HY.purchased from Santa Cruz Biotechnology. D17 and the LMeC cell lines were transfected with siCOX‐2 (sc‐29279), while cADSCs were transfected with siTSG‐6 (sc‐39819). The control group was transfected with control

(6) COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated miceCancer lettersApril 1, 2021Gonçalves RM, Delgobo M, Agnes JP, das Neves RN, Falchetti M, Casagrande T, Garcia APV, Vieira TC, Somensi N, Bruxel MA, et al.

(7) Extracellular vesicles derived from DFO-preconditioned canine AT-MSCs reprogram macrophages into M2 phasePloS oneJanuary 1, 2021Park SM, An JH, Lee JH, Kim KB, Chae HK, Oh YI, Song WJ, Youn HY.confluency of cAT-MSC was approximately 40%, they were transfected with COX-2 siRNA or control siRNA (sc-29279 and sc-37007, respectively; Santa Cruz Biotechnology, Santa Cruz, CA, USA) for 48 h using Lipofectamine

(8) Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophyRedox biologyJanuary 1, 2021Chen H, Qian Z, Zhang S, Tang J, Fang L, Jiang F, Ge D, Chang J, Cao J, Yang L, et al.

(9) Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammationJCI insightJune 18, 2020Lee HJ, Ko JH, Kim HJ, Jeong HJ, Oh JY.

(10) Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue HomeostasisCell reportsMarch 17, 2020Ko JH, Kim HJ, Jeong HJ, Lee HJ, Oh JY.

(11) Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE(2) pathwayArthritis research & therapyJuly 8, 2019Peng A, Lu X, Huang J, He M, Xu J, Huang H, Chen Q.

(12) LincRNA Cox-2 Regulates Lipopolysaccharide-Induced Inflammatory Response of Human Peritoneal Mesothelial Cells via Modulating miR-21/NF-κB AxisMediators of inflammationJanuary 1, 2019Bian Y, Yang L, Zhang B, Li W, Wang S, Jiang S, Chen X, Li W, Zeng L.

(13) Tumor-associated macrophages induce invasion and poor prognosis in human gastric cancer in a cyclooxygenase-2/MMP9-dependent mannerAmerican journal of translational researchJanuary 1, 2019Xu J, Yu Y, He X, Niu N, Li X, Zhang R, Hu J, Ma J, Yu X, Sun Y, et al.

(14) Silibinin attenuates TGF‑β1‑induced migration and invasion via EMT suppression and is associated with COX‑2 downregulation in bladder transitional cell carcinomaOncology reportsDecember 1, 2018Li F, Sun Y, Jia J, Yang C, Tang X, Jin B, Wang K, Guo P, Ma Z, Chen Y, et al.Dilutions for primary and secondary antibodies were 1:1,000 and 1:3,000 respectively. COX‑2 siRNA (cat. no. sc‑29279) was from Santa Cruz Biotechnology, Inc. (Dallas, TX, USA) (20). Silibinin, MTT, proteinase and phosphatase

(15) Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic CancersMolecular cancer therapeuticsDecember 1, 2018Maust JD, Frankowski-McGregor CL, Bankhead A 3rd, Simeone DM, Sebolt-Leopold JS.

(16) The down-regulation of microRNA-137 contributes to the up-regulation of retinoblastoma cell proliferation and invasion by regulating COX-2/PGE2 signalingBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieOctober 1, 2018Zhang J, He J, Zhang L.

(17) Transactivation of PTGS2 by PAX5 signaling potentiates cisplatin resistance in muscle-invasive bladder cancer cellsBiochemical and biophysical research communicationsSeptember 18, 2018Dong BW, Zhang WB, Qi SM, Yan CY, Gao J.

(18) Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cellsCancer lettersJuly 1, 2018Zanotto-Filho A, Rajamanickam S, Loranc E, Masamsetti VP, Gorthi A, Romero JC, Tonapi S, Gonçalves RM, Reddick RL, Benavides R, et al.duplexes targeting human IL8 (sc-39631), CXCL2 (sc-43934), MMP1 (sc-41552), VEGFA (sc-29520) PTGS2/COX-2 (sc-29279) and scrambled siRNA-A (sc-37007) were purchased from Santa Cruz Biotechnology, and incubated at 20

(19) COX-2 Forms Regulatory Loop with YAP to Promote Proliferation and Tumorigenesis of Hepatocellular Carcinoma CellsNeoplasia (New York, N.Y.)April 1, 2018Xu G, Wang Y, Li W, Cao Y, Xu J, Hu Z, Hao Y, Hu L, Sun Y.

(20) COX-2-dependent and independent effects of COX-2 inhibitors and NSAIDs on proatherogenic changes in human monocytes/macrophagesJournal of investigative medicine : the official publication of the American Federation for Clinical ResearchMarch 1, 2017Voloshyna I, Kasselman LJ, Carsons SE, Littlefield MJ, Gomolin IH, De Leon J, Reiss AB.

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Cox-2 siRNA (h)

Cox-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Cox-2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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