HDAC6 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHDAC6 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35544
Gene Namehistone deacetylase 6
Quantity10 µM
Specieshuman
NCBI Full Gene Namehistone deacetylase 6
NCBI Gene AliasesCPBHM, HD6, JM21, PPP1R90
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Tip60-HDAC8-SMURF2-mediated β-TrCP1 degradation is a key mechanism for hypoxia-induced cell death and tissue injuryCellular and Molecular Life SciencesDecember 27, 2025Sheng Li, Bo-Wen Zhang, Zi-Juan Wei, Yan Xi, Guo-An Zhang, Yue Zhang, De-Chi Kou, Xiao-Peng Song, Jing Huang, Ping Song, et al.(sc-41675), HDAC1 (sc-44208), HDAC2 (sc-29345), HDAC3 (sc-35538), HDAC4 (sc-35540), HDAC5 (sc-35542), HDAC6 (sc-35544), HDAC7 (sc-35546), HDAC8 (sc-35548), HDAC9 (sc-35550), HDAC10 (sc-72307) and HDAC11 (sc-106896) were

(2) Inhibition of HDAC6 alleviates cancer‑induced bone pain by reducing the activation of NLRP3 inflammasomeInternational Journal of Molecular MedicineNovember 17, 2023Yin-Di Hu, Zhao-Di Wang, Yuan-Fen Yue, Dai Li, Shu-Qing Zhen, Jie-Qiong Ding, Wei Meng, Hai-Li Zhu, Min Xie, Ling Liufrom Beyotime Institute of Biotechnology. The commercial products HDAC6 short interfering (si) RNA (sc-35544), siRNA Transfection Medium (sc-36868), siRNA Transfection Reagent (sc-29528) and control siRNA (sc-37007)

(3) HDAC6 promotes aggressive development of liver cancer by improving egfr mRNA stabilityNeoplasia (New York, N.Y.)January 1, 2023Dai HY, Chang LS, Yang SF, Wang SN, Su SJ, Yeh YT.at 37°C in an incubator with 5% CO2. The cells were transfected with 50 nM of siRNA targeting HDAC6 (sc-35544, Santa Cruz Biotechnology Inc., CA, USA), HDAC6-Flag (Addgene plasmid number #13823), dominant-negative

(4) Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2Scientific reportsMarch 13, 2020Bora-Singhal N, Mohankumar D, Saha B, Colin CM, Lee JY, Martin MW, Zheng X, Coppola D, Chellappan S.50 μm was counted as mentioned above. siRNA transfections The siRNAs for HDAC1 (sc-29343) HDAC6 (sc-35544) and HDAC11 (sc-106896) were purchased from Santa Cruz Biotechnologies. The siRNAs were transfected

(5) Histone deacetylase 6 reduction promotes aortic valve calcification via an endoplasmic reticulum stress-mediated osteogenic pathwayThe Journal of thoracic and cardiovascular surgeryAugust 1, 2019Fu Z, Li F, Jia L, Su S, Wang Y, Cai Z, Xiang M.

(6) The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate CancerMolecular cancer research : MCRJanuary 1, 2019Manca S, Frisbie CP, LaGrange CA, Casey CA, Riethoven JM, Petrosyan A.

(7) Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cellsLife sciencesNovember 15, 2018Yang F, Wang F, Liu Y, Wang S, Li X, Huang Y, Xia Y, Cao C.

(8) HDAC and Ku70 axis- an effective target for apoptosis induction by a new 2-cyano-3-oxo-1,9-dien glycyrrhetinic acid analogueCell death & diseaseMay 24, 2018Gong P, Li K, Li Y, Liu D, Zhao L, Jing Y.

(9) A potent hydroxamic acid-based, small-molecule inhibitor A452 preferentially inhibits HDAC6 activity and induces cytotoxicity toward cancer cells irrespective of p53 statusCarcinogenesisJanuary 12, 2018Ryu HW, Shin DH, Lee DH, Won HR, Kwon SH.

(10) EGF-Mediated Overexpression of Myc Attenuates miR-26b by Recruiting HDAC3 to Induce Epithelial-Mesenchymal Transition of Lens Epithelial CellsBioMed research internationalJanuary 1, 2018Dong N, Xu B, Xu J.

(11) The role of Runx2 in facilitating autophagy in metastatic breast cancer cellsJournal of cellular physiologyJanuary 1, 2018Tandon M, Othman AH, Ashok V, Stein GS, Pratap J.

(12) Histone deacetylase 6 inhibition counteracts the epithelial-mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosisOncotargetOctober 24, 2017Xu L, Liu N, Gu H, Wang H, Shi Y, Ma X, Ma S, Ni J, Tao M, Qiu A, et al.

(13) HDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cellsCancer lettersJuly 1, 2017Marampon F, Megiorni F, Camero S, Crescioli C, McDowell HP, Sferra R, Vetuschi A, Pompili S, Ventura L, De Felice F, et al.

(14) The possible prognostic role of histone deacetylase and transforming growth factor β/Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical studyEuropean journal of histochemistry : EJHMay 16, 2017Sferra R, Pompili S, Festuccia C, Marampon F, Gravina GL, Ventura L, Di Cesare E, Cicchinelli S, Gaudio E, Vetuschi A.GenBank. A pool of 3 target-specific 19-25 small interfering RNAs (siRNAs) were used to knock-down HDAC6 (sc- 35544, Santa Cruz Biotechnology, Ltd.) gene expression. Transfections were performed following Santa Cruz Biotechnology

(15) TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent MechanismCancer researchDecember 1, 2016New M, Sheikh S, Bekheet M, Olzscha H, Thezenas ML, Care MA, Fotheringham S, Tooze RM, Kessler B, La Thangue NB.

(16) Inhibition of HDAC6 Protein Enhances Bortezomib-induced Apoptosis in Head and Neck Squamous Cell Carcinoma (HNSCC) by Reducing AutophagyThe Journal of biological chemistryAugust 26, 2016Chang I, Wang CY.

(17) Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 functionAmerican journal of physiology. Lung cellular and molecular physiologyDecember 15, 2015Joshi AD, Barabutis N, Birmpas C, Dimitropoulou C, Thangjam G, Cherian-Shaw M, Dennison J, Catravas JD.selective HDAC6 inhibitor tubastatin were purchased from Selleck Chemicals. HDAC3 (sc-35538), HDAC6 (sc-35544), and control small-interfering RNA (siRNA, sc-37007) were purchased from Santa Cruz Biotechnology.

(18) Histone deacetylase 6 inhibits influenza A virus release by downregulating the trafficking of viral components to the plasma membrane via its substrate, acetylated microtubulesJournal of virologyOctober 1, 2014Husain M, Cheung CY.Predesigned small interfering RNA (siRNA) oligonucleotides targeting the HDAC6 gene (catalogue number sc-35544) and a nontargeting control (catalogue number sc37007) were purchased from Santa Cruz Biotechnology.

(19) Class I-specific histone deacetylase inhibitor MS-275 overrides TRAIL-resistance in melanoma cells by downregulating c-FLIPInternational immunopharmacologyAugust 1, 2014Venza I, Visalli M, Oteri R, Teti D, Venza M.

(20) Inhibition of HDAC6 deacetylase activity increases its binding with microtubules and suppresses microtubule dynamic instability in MCF-7 cellsThe Journal of biological chemistryAugust 2, 2013Asthana J, Kapoor S, Mohan R, Panda D.

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HDAC6 siRNA (h)

HDAC6 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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HDAC6 siRNA (h) from Santa Cruz Biotechnology, Inc.

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