gp91-phox siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
Itemgp91-phox siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35503
Gene Namecytochrome b-245, beta polypeptide
Quantity10 µM
Specieshuman
NCBI Full Gene Namecytochrome b-245 beta chain
NCBI Gene AliasesAMCBX2, CGD, CGDX, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin IIAntioxidants (Basel)April 22, 2024Michael Adu-Gyamfi, Claudia Goettsch, Julian Kamhieh-Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunssen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, et al.co-transfected control vectors. Transient transfections of HMECs with siRNAs targeting NOX1 (sc-43939), NOX2 (sc-35503), NOX4 (sc-41586), OCT1 (sc-42552), or a scrambled siRNA control (sc-37007) (all from Santa Cruz Biotechnology,

(2) Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidationCell reportsNovember 28, 2023Kang DH, Kim Y, Min S, Lee SY, Chung KY, Baek IJ, Kwon K, Jo H, Kang SW.al.10,https://doi.org/10.1016/j.molcel.2011.08.040. 5′- CCA ACG UGA UAU UCC UUG A −3′,, siRNA sequence for NOX2,Santa Cruz,Cat# sc-35503 5′- GAA CAG GCU AAG GAU ACU A −3′,, siRNA sequence for NOX4,Santa Cruz,Cat# sc-41586 5′- AAC GAA

(3) Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injuryAging (Albany NY)November 17, 2023Saisudha Koka, Sreenidhi Surineni, Gurinder Bir Singh, Krishna M. Boiniovernight with primary antibodies, including anti-gp91phox (1:200 dilution, Santa Cruz, USA, Cat # Sc35503) and anti-p47phox (1:200 dilution, Santa Cruz, USA, Cat # Sc376614) for mouse antibodies. To detect

(4) The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent mannerRedox biologyJune 1, 2022Tarafdar A, Wolska N, Krisp C, Schlüter H, Pula G.concentration of 0.2% v/v. For gene silencing with siRNA, HUVECs were transfected with NOX1 (#sc-43939), NOX2 (#sc-35503), NOX4 (#sc-41586), NOX5 (#sc-45486) or scrambled control (#sc-37007) siRNAs (Santa Cruz Biotechnology)

(5) IL-23 production in human macrophages is regulated negatively by tumor necrosis factor α-induced protein 3 and positively by specificity protein 1 after stimulation of the toll-like receptor 7/8 signaling pathwayHeliyonFebruary 1, 2022Yamaguchi R, Sakamoto A, Yamaguchi R, Haraguchi M, Narahara S, Sugiuchi H, Yamaguch Y.

(6) Xanthohumol Induces ROS through NADPH Oxidase, Causes Cell Cycle Arrest and ApoptosisOxidative medicine and cellular longevityJanuary 1, 2021Wang CM, Chen J, Zhao J, Hu SS, Zhang SQ, Mi XQ, Shi X, Cao XH, Li Z.confocal microscope (LeicaTCS SP8). 2.9. siRNA-Mediated gp91phox Gene Silencing siRNA against gp91phox (sc-35503), related RT-PCR Primer (sc-35503-PR), Control siRNA (sc-37007), and siRNA Reagent System (sc-45064)

(7) Hyperglycemia Induces Myocardial Dysfunction via Epigenetic Regulation of JunDCirculation researchOctober 23, 2020Hussain S, Khan AW, Akhmedov A, Suades R, Costantino S, Paneni F, Caidahl K, Mohammed SA, Hage C, Gkolfos C, et al.

(8) Corilagin ameliorates sleep deprivation-induced memory impairments by inhibiting NOX2 and activating Nrf2Brain research bulletinJuly 1, 2020Wang W, Yang L, Liu T, Ma Y, Huang S, He M, Wang J, Wen A, Ding Y.

(9) Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4Oxidative medicine and cellular longevityJanuary 1, 2020Huang Y, Li X, Zhang X, Tang J.inoculated in 6-well plates and transfected with 20 nM control siRNA or validated NOX2 siRNA (cat. no. sc-35503) or NOX4 siRNA (cat. no. sc-36149) from Santa Cruz Biotechnology, Inc., using RPMI 1640 media. Brieﬂy, 5

(10) Distinct Redox Signalling following Macrophage Activation Influences Profibrotic ActivityJournal of immunology researchJanuary 1, 2019Lewis CV, Vinh A, Diep H, Samuel CS, Drummond GR, Kemp-Harper BK.detection. A subset of macrophages were treated in the presence of 100 nM NOX2 siRNA (Santa-Cruz no. sc-35503) or missense siRNA Journal of Immunology Research (control siRNA-A; Santa-Cruz no. sc-37007). These

(11) Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent AngiogenesisAntioxidants & redox signalingJanuary 10, 2018Vara D, Watt JM, Fortunato TM, Mellor H, Burgess M, Wicks K, Mace K, Reeksting S, Lubben A, Wheeler-Jones CPD, et al.5 mM EDTA, 50 mM Tris, pH 7.4). siRNA-mediated gene silencing HUVECs were transfected with NOX2 (sc-35503), NOX4 (sc-41586), p65 NF-κB (sc-29410), p22phox (sc-36149), or scrambled control (sc-37007) siRNAs

(12) Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular functionRedox biologyOctober 1, 2017Mahmoud AM, Ali MM, Miranda ER, Mey JT, Blackburn BK, Haus JM, Phillips SA.

(13) Activation of NADPH oxidases leads to DNA damage in esophageal cellsScientific reportsAugust 30, 2017Bhardwaj V, Gokulan RC, Horvat A, Yermalitskaya L, Korolkova O, Washington KM, El-Rifai W, Dikalov SI, Zaika AI.used for downregulation of the following targets: NOX1 (HSS178286, ThermoFisher, Waltham, MA), NOX2 (sc-35503, Santa Cruz Biotechnology, Dallas, TX), PKCα (sc-36243, Santa Cruz Biotechnologies), PKCβ (s11095, ThermoFisher,

(14) ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesisAmerican journal of physiology. Cell physiologyJune 1, 2017Kim YM, Kim SJ, Tatsunami R, Yamamura H, Fukai T, Ushio-Fukai M.to 50% confluence in 100-mm dishes and transfected with 20 nM control siRNA or validated Nox2 siRNA (sc-35503) or p22phox siRNA (sc-36149) from Santa Cruz (43) using Oligofectamine, as we reported (40, 65). Cells

(15) Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cellsOncotargetApril 25, 2017Tsai MH, Liu JF, Chiang YC, Hu SC, Hsu LF, Lin YC, Lin ZC, Lee HC, Chen MC, Huang CL, et al.flow cytometer. Cell transfection of siRNAs The human p47phox siRNA (SC-29422), Nox2 siRNA (gp91phox, SC35503) and scrambled siRNA (SC-37007) were purchased from Santa Cruz Biotechnology (CA, USA). Transient transfections

(16) High oxidative stress adversely affects NFκB mediated induction of inducible nitric oxide synthase in human neutrophils: Implications in chronic myeloid leukemiaNitric oxide : biology and chemistryAugust 31, 2016Singh AK, Awasthi D, Dubey M, Nagarkoti S, Kumar A, Chandra T, Barthwal MK, Tripathi AK, Dikshit M.

(17) Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunctionScientific reportsJune 17, 2016Lee CW, Lin ZC, Hu SC, Chiang YC, Hsu LF, Lin YC, Lee IT, Tsai MH, Fang JY.Transient transfection with siRNAs SMARTpool RNA duplexes corresponding to human p47phox(SC-29422), Nox2 (gp91phox, SC35503) and scrambled siRNA (SC-37007) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA). JNK1/2

(18) Inhibition of Mitochondrial Fission and NOX2 Expression Prevent NLRP3 Inflammasome Activation in the Endothelium: The Role of Corosolic Acid Action in the Amelioration of Endothelial DysfunctionAntioxidants & redox signalingJune 1, 2016Li Y, Zhou ZH, Chen MH, Yang J, Leng J, Cao GS, Xin GZ, Liu LF, Kou JP, Liu BL, et al.

(19) Effects of NOX1 on fibroblastic changes of endothelial cells in radiation‑induced pulmonary fibrosisMolecular medicine reportsMay 1, 2016Choi SH, Kim M, Lee HJ, Kim EH, Kim CH, Lee YJ.

(20) SLAMF1 regulation of chemotaxis and autophagy determines CLL patient responseThe Journal of clinical investigationJanuary 1, 2016Bologna C, Buonincontri R, Serra S, Vaisitti T, Audrito V, Brusa D, Pagnani A, Coscia M, D'Arena G, Mereu E, et al.

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gp91-phox siRNA (h)

gp91-phox siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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gp91-phox siRNA (h) from Santa Cruz Biotechnology, Inc.

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