DNA-PKCS siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDNA-PKCS siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35200
Gene Nameprotein kinase, DNA activated, catalytic polypeptide
Quantity10 µM
Specieshuman
NCBI Full Gene Nameprotein kinase, DNA-activated, catalytic subunit
NCBI Gene AliasesDNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) DNA-PKcs promotes therapy resistance and metastatic recurrence in neuroblastomaCancer LettersMay 28, 2026Mahnaz Norouzi, Subin Kim, Beibei Zhu, Chi Wang, Natalie Wu, Katherine Somers, Eddy Shih-Hsin Yang, B. Mark Mark Evers, Eric J. Rellinger, Piotr Rychahoutransductions and stable knockdown (shRNA transfection). Lentiviral plasmids encoding shRNA PRKDC (SC-35200) and non-target control (NTC) shRNA were obtained from Santa Cruz Biotechnology (Santa Cruz, CA). BE(2)-C

(2) DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTROncotargetFebruary 18, 2020Zicari S, Sharma AL, Sahu G, Dubrovsky L, Sun L, Yue H, Jada T, Ochem A, Simon G, Bukrinsky M, et al.

(3) The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor networkCell cycle (Georgetown, Tex.)November 1, 2019Wang B, Li D, Yao Y, Heyns M, Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Bronson RT, Metz GAS, Kovalchuk O, et al.

(4) NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA RepairCell reportsFebruary 19, 2019Munnur D, Somers J, Skalka G, Weston R, Jukes-Jones R, Bhogadia M, Dominguez C, Cain K, Ahel I, Malewicz M.

(5) Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis inductionPloS oneJanuary 1, 2019Choi C, Son A, Lee GH, Shin SW, Park S, Ahn SH, Chung Y, Yu JI, Park HC.confluence in 10-cm dishes a day before transfection. The control siRNAs (sc-37007) and DNA-PKcs siRNAs (sc-35200) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) and diluted to 10 nM of the final

(6) DHX9 regulates production of hepatitis B virus-derived circular RNA and viral protein levelsOncotargetApril 20, 2018Sekiba K, Otsuka M, Ohno M, Kishikawa T, Yamagami M, Suzuki T, Ishibashi R, Seimiya T, Tanaka E, Koike K.

(7) AZD9291 Increases Sensitivity to Radiation in PC-9-IR Cells by Delaying DNA Damage Repair after Irradiation and Inducing ApoptosisRadiation researchMarch 1, 2018Wu S, Zhu L, Tu L, Chen S, Huang H, Zhang J, Ma S, Zhang S.

(8) DNA-Pk(CS) expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgeryHead & neckFebruary 1, 2017Weaver AN, Cooper TS, Wei S, Carroll WR, Rosenthal EL, Yang ES.

(9) Identification of DNA-PKcs as a primary resistance factor of salinomycin in osteosarcoma cellsOncotargetNovember 29, 2016Zhen YF, Li ST, Zhu YR, Wang XD, Zhou XZ, Zhu LQ.

(10) Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 ExpressionJournal of immunology (Baltimore, Md. : 1950)November 15, 2016Pignoloni B, Fionda C, Dell'Oste V, Luganini A, Cippitelli M, Zingoni A, Landolfo S, Gribaudo G, Santoni A, Cerboni C.pool (siCtrl) were purchased from Dharmacon (Thermo Fisher Scientific). siRNA specific for DNA-PKCS (sc-35200) (siDNA-PK) was from Santa Cruz Biotechnology. HFFs (70–80% confluence) were transfected with 100–200

(11) Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cellsCancer biology & therapyNovember 1, 2016Rahal ON, Fatfat M, Hankache C, Osman B, Khalife H, Machaca K, Muhtasib HG.

(12) CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-κB pathway in multidrug-resistant glioblastoma cells in vitroOncogeneJanuary 14, 2016Xi G, Hayes E, Lewis R, Ichi S, Mania-Farnell B, Shim K, Takao T, Allender E, Mayanil CS, Tomita T.instructions. PSC-833 (sc361298), a speciﬁc MDR1 inhibitor; AKT inhibitor IV (sc-203809); siDNA-PKcs (sc-35200), siNF-κB/p65 (sc-29410), their scrambled controls, and associated transfection reagents were purchased

(13) DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600Biochemical and biophysical research communicationsOctober 23, 2015Wu L, Zhang J, Wu H, Han E.

(14) Mechanism of heat stress-induced cellular senescence elucidates the exclusive vulnerability of early S-phase cells to mild genotoxic stressNucleic acids researchJuly 27, 2015Velichko AK, Petrova NV, Razin SV, Kantidze OL.

(15) Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapyOncotargetJune 10, 2015Lamb R, Fiorillo M, Chadwick A, Ozsvari B, Reeves KJ, Smith DL, Clarke RB, Howell SJ, Cappello AR, Martinez-Outschoorn UE, et al.

(16) DNA-PKcs deficiency inhibits glioblastoma cell-derived angiogenesis after ionizing radiationJournal of cellular physiologyMay 1, 2015Liu Y, Zhang L, Liu Y, Sun C, Zhang H, Miao G, Di CX, Zhou X, Zhou R, Wang Z.

(17) Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutationOncotargetMarch 20, 2015Zhang S, Zheng X, Huang H, Wu K, Wang B, Chen X, Ma S.

(18) DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4⁺ T-cell function without causing severe combined immunodeficiencyThe Journal of allergy and clinical immunologyFebruary 1, 2015Ghonim MA, Pyakurel K, Ju J, Rodriguez PC, Lammi MR, Davis C, Abughazleh MQ, Mansy MS, Naura AS, Boulares AH.

(19) DNA-PKcs plays role in cancer metastasis through regulation of secreted proteins involved in migration and invasionCell cycle (Georgetown, Tex.)January 1, 2015Kotula E, Berthault N, Agrario C, Lienafa MC, Simon A, Dingli F, Loew D, Sibut V, Saule S, Dutreix M.

(20) DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathwayMolecular and cellular biochemistryJanuary 1, 2015Fang Y, Chai Z, Wang D, Kuang T, Wu W, Lou W.

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DNA-PKCS siRNA (h)

DNA-PKCS siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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DNA-PKCS siRNA (h) from Santa Cruz Biotechnology, Inc.

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