DRP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDRP1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-43732
Gene Namedynamin 1-like
Quantity10 µM
Specieshuman
NCBI Full Gene Namedynamin 1 like
NCBI Gene AliasesDLP1, DRP1, DVLP, DYMPLE, EMPF, EMPF1, HDYNIV, OPA5
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cellsCell Death DiscoveryFebruary 26, 2026Roberta Gonnella, Vincenzo Corrado, Giulio Francesco Scaffidi, Rossella Benedetti, Michele Di Crosta, Roberta Zarrella, Maria Saveria Gilardini Montani, Roberta Santarelli, Mara Cironemanufacturer’s instructions (Santa Cruz Biotechnology, Inc., Heidelberg, Germany, sc-29350, sc-35597, and sc-43732 respectively). PEL cells were seeded in six-wells culture plates at a concentration of 4 × 105/ml in

(2) Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian canceriScienceSeptember 15, 2023Ghosh D, Pakhira S, Ghosh DD, Roychoudhury S, Roy SS.

(3) DRP1 Inhibition Enhances Venetoclax-Induced Mitochondrial Apoptosis in TP53-Mutated Acute Myeloid Leukemia Cells through BAX/BAK ActivationCancersJanuary 25, 2023Jang JE, Hwang DY, Eom JI, Cheong JW, Jeung HK, Cho H, Chung H, Kim JS, Min YH.

(4) Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagyRedox biologyJune 1, 2022Jiang Y, Krantz S, Qin X, Li S, Gunasekara H, Kim YM, Zimnicka A, Bae M, Ma K, Toth PT, et al.

(5) Cardiomyocyte mitochondrial dynamic-related lncRNA 1 (CMDL-1) may serve as a potential therapeutic target in doxorubicin cardiotoxicityMolecular therapy. Nucleic acidsSeptember 3, 2021Aung LHH, Chen X, Cueva Jumbo JC, Li Z, Wang SY, Zhao C, Liu Z, Wang Y, Li P.

(6) Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signalingNature communicationsMay 12, 2021Kim YM, Krantz S, Jambusaria A, Toth PT, Moon HG, Gunarathna I, Park GY, Rehman J.Leuven, Belgium. We obtained siRNA for beta-catenin (sc-29209), Mfn2 (sc-43928), Mfn1 (sc-43927), Drp1 (sc-43732), Opa1(sc-106808) or control (sc-37007) from Santa Cruz Biotechnologies. Lentivirus production and

(7) Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activationJournal of ethnopharmacologyMay 10, 2021Qin W, Tong X, Liang R, Tang K, Wu X, Jia Y, Tan N.

(8) Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentationCellular and molecular life sciences : CMLSMay 1, 2021Prasad P, Ghosh S, Roy SS.

(9) Crohn's Disease Pathobiont Adherent-Invasive E coli Disrupts Epithelial Mitochondrial Networks With Implications for Gut PermeabilityCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Mancini NL, Rajeev S, Jayme TS, Wang A, Keita ÅV, Workentine ML, Hamed S, Söderholm JD, Lopes F, Shutt TE, et al.with E coli.21 siRNA Knock-Down of Drp1 Drp1 expression was knocked-down using siRNA (Drp1 siRNA, sc-43732; Santa Cruz Biotechnology, TX; control nontargeted siRNA, sc-37007; Santa Cruz Biotechnology) and Lipofectamine

(10) Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor MicroenvironmentDevelopmental cellOctober 26, 2020Bertolini I, Ghosh JC, Kossenkov AV, Mulugu S, Krishn SR, Vaira V, Qin J, Plow EF, Languino LR, Altieri DC.Santa Cruz Biotech) or Akt2 (sc-29197, Santa Cruz Biotech), MFN1 (sc-270320, Santa Cruz Biotech) and Drp1 (sc-43732, Santa Cruz Biotech). For gene silencing experiments, pooled or individual siRNA oligonucleotide sequences

(11) Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial FissionCardiovascular drugs and therapyOctober 1, 2020Lu ZY, Qi J, Yang B, Cao HL, Wang RY, Wang X, Chi RF, Guo CL, Yang ZM, Liu HM, et al.

(12) Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancerCancer lettersFebruary 28, 2020Lee YG, Nam Y, Shin KJ, Yoon S, Park WS, Joung JY, Seo JK, Jang J, Lee S, Nam D, et al.

(13) ROCK1 activation-mediated mitochondrial translocation of Drp1 and cofilin are required for arnidiol-induced mitochondrial fission and apoptosisJournal of experimental & clinical cancer research : CRFebruary 19, 2020Hu J, Zhang H, Li J, Jiang X, Zhang Y, Wu Q, Shen L, Shi J, Gao N.

(14) The Causal Role of Mitochondrial Dynamics in Regulating Innate Immunity in DiabetesFrontiers in endocrinologyJanuary 1, 2020Chang YH, Lin HY, Shen FC, Su YJ, Chuang JH, Lin TK, Liou CW, Lin CY, Weng SW, Wang PW.(Technologies, Inc., Rockville, MD, USA). For siRNA knockdown, interfering RNAs (sc-43927; sc-43928; sc-43732; sc-60643; Santa Cruz Biotechnology, Santa Cruz, CA) were delivered using Lipofectamine R 2000 (1367620,

(15) Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of MitofusinCell metabolismApril 2, 2019Wu MJ, Chen YS, Kim MR, Chang CC, Gampala S, Zhang Y, Wang Y, Chang CY, Yang JY, Chang CJ.

(16) Paris Saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-κB pathwayPharmacological researchJanuary 1, 2019Chen M, Ye K, Zhang B, Xin Q, Li P, Kong AN, Wen X, Yang J.

(17) Macrophage migration inhibitory factor regulates mitochondrial dynamics and cell growth of human cancer cell lines through CD74-NF-κB signalingThe Journal of biological chemistryDecember 21, 2018De R, Sarkar S, Mazumder S, Debsharma S, Siddiqui AA, Saha SJ, Banerjee C, Nag S, Saha D, Pramanik S, et al.

(18) Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cellsCell death discoveryDecember 1, 2018Hoque A, Sivakumaran P, Bond ST, Ling NXY, Kong AM, Scott JW, Bandara N, Hernández D, Liu GS, Wong RCB, et al.TeSR-E8 medium. For knockdown experiments, Drp1 (DNM1L) was silenced with 50 pmol of siRNA duplex (sc-43732; Santa Cruz Biotechnology, TX, USA). CK2α (CSNK2A1) and CK2α′ (CSNK2A2) were silenced with 50 pmol of

(19) Fragmentation level determines mitochondrial damage response and subsequently the fate of cancer cells exposed to carbon ionsRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and OncologyOctober 1, 2018Jin X, Zheng X, Li F, Liu B, Li H, Hirayama R, Li P, Liu X, Shen G, Li Q.

(20) The Causal Role of Mitochondrial Dynamics in Regulating Insulin Resistance in Diabetes: Link through Mitochondrial Reactive Oxygen SpeciesOxidative medicine and cellular longevityJanuary 1, 2018Lin HY, Weng SW, Chang YH, Su YJ, Chang CM, Tsai CJ, Shen FC, Chuang JH, Lin TK, Liou CW, et al.RG202046; RG202560; Origene Technologies, Inc., Rockville, MD, USA) and siRNA (sc-43927; sc-43928; sc-43732; sc-60643; Santa Cruz Biotechnology, Santa Cruz, CA) spanned 24 and 48 h, respectively. Mock control

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DRP1 siRNA (h)

DRP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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DRP1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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