TERT siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTERT siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-36641
Gene Nametelomerase reverse transcriptase
Quantity10 µM
Specieshuman
NCBI Full Gene Nametelomerase reverse transcriptase
NCBI Gene AliasesCMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Inhibition of hTERT/telomerase/telomere mediates therapeutic efficacy of osimertinib in EGFR mutant lung cancerJournal of Experimental MedicineNovember 4, 2024Zhen Chen, Karin A. Vallega, Dongsheng Wang, Zihan Quan, Songqing Fan, Qiming Wang, Ticiana Leal, Suresh S. Ramalingam, Shi-Yong SunLiu (Ohio State University; Columbus, OH, USA). Gene knockdown using siRNA and shRNA hTERT siRNA (sc-36641), hTERT shRNA plasmid (sc-36641-SH), c-Myc siRNA (sc-29226), and c-Myc shRNA plasmid (sc-29226-SH) were

(2) hTERT-molecular targeted therapy of ovarian cancer cells via folate-functionalized PLGA nanoparticles co-loaded with MNPs/siRNA/wortmanninLife sciencesJuly 15, 2021Ghareghomi S, Ahmadian S, Zarghami N, Hemmati S.

(3) Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasivenessMolecular oncologyJuly 1, 2021Bernabé-García M, Martínez-Balsalobre E, García-Moreno D, García-Castillo J, Revilla-Nuin B, Blanco-Alcaina E, Mulero V, Alcaraz-Pérez F, Cayuela ML.were transfected with a ready‐to‐use siRNA for human TERT [TERT siRNA (h), Santa Cruz Biotechnology, #sc‐36641] or for human Patched 1 (PTCH1; PTCH1 siRNA (h), Santa Cruz Biotechnology, #sc‐91304), at a final concentration

(4) 6-Dithio-2'-deoxyguanosine analogs induce reactive oxygen species-mediated tumor cell apoptosis via bi-targeting thioredoxin 1 and telomeraseToxicology and applied pharmacologyAugust 15, 2020Zhang Y, Zhou J, Ye Q, Zeng K, Pan J, Chen L, Wang Y, Yang B, He Q, Gao J, et al.

(5) Camptothecin induces c-Myc- and Sp1-mediated hTERT expression in LNCaP cells: Involvement of reactive oxygen species and PI3K/AktFood and chemical toxicology : an international journal published for the British Industrial Biological Research AssociationMay 1, 2019Dilshara MG, Jayasooriya RGPT, Choi YH, Kim GY.

(6) Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancerNature communicationsFebruary 8, 2018Liu R, Zhang T, Zhu G, Xing M.western blotting images are shown in Supplementary Figs. 3−8. Transient TERT or MYC knockdown TERT siRNA (#sc-36641) and negative control siRNA (#sc-37007) were purchased from Santa Cruz Biotechnology. MYC esiRNA (#EHU021051)

(7) Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase ActivityScientific reportsMarch 3, 2017Cheung DH, Ho ST, Lau KF, Jin R, Wang YN, Kung HF, Huang JJ, Shaw PC.immunoprecipitation experiments with hTERT, PinX1 or NPM down-regulation, 80 pmole of hTERT siRNA (sc-36641, Santa Cruz, USA), PinX1 siRNA or NPM siRNA (On-Target Plus SmartPool, Dharmacon, USA) was transfected

(8) Telomerase activity in the occurrence and progression of oral squamous cell carcinomaJournal of oral scienceJanuary 1, 2015Miyazaki Y, Yoshida N, Nozaki T, Inoue H, Kikuchi K, Kusama K.

(9) Enhancement of adriamycin cytotoxicity by sodium butyrate involves hTERT downmodulation-mediated apoptosis in human uterine cancer cellsMolecular carcinogenesisJuly 1, 2014Yu M, Kong H, Zhao Y, Sun X, Zheng Z, Yang C, Zhu Y.

(10) miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivoExperimental cell researchJune 10, 2013Chakrabarti M, Banik NL, Ray SK.

(11) ES micro-environment enhances stemness and inhibits apoptosis in human limbal stem cells via the maintenance of telomerase activityPloS oneJanuary 1, 2013Liu Z, Wan P, Duan H, Zhou J, Tan B, Liu Y, Zhou Q, Zhou C, Huang Z, Tian B, et al.

(12) BRCA1 localization to the telomere and its loss from the telomere in response to DNA damageThe Journal of biological chemistryDecember 25, 2009Ballal RD, Saha T, Fan S, Haddad BR, Rosen EM.

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TERT siRNA (h)

TERT siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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TERT siRNA (h) from Santa Cruz Biotechnology, Inc.

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