Calpain 2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCalpain 2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-41459
Gene Namecalpain 2
Quantity10 µM
Specieshuman
NCBI Full Gene Namecalpain 2
NCBI Gene AliasesCANP2, CANPL2, CANPml, mCANP
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Calpain-2 facilitates infection of the intracellular bacteria Listeria monocytogenes and invasion intestinal immune barrier by impairing nitric oxide homeostasisJournal of Advanced ResearchMay 1, 2026Bo Yao, Jingru Wang, Dingyu Hou, Weiming Liu, Chenke Xie, Kaiyuan Shi, Wenyi Han, Xiaofeng Miao, Jun Chen, Zhihui Cai, et al.with L. monocytogenes at a MOI of 20 or transfected with CAPN2-specific small interfering RNA (siRNA; sc-41459, Santa Cruz Biotechnology) for the indicated time periods. Subsequently, cells were fixed with 4 % paraformaldehyde

(2) Neuroprotective Effects of Calpain Inhibition in Parkinson’s Disease: Insights from Cellular and Murine ModelsCellsAugust 24, 2025Vandana Zaman, Amy Gathings, Kelsey P. Drasites, Donald C. Shields, Narendra L. Banik, Azizul HaqueCells Commercially available Santa Cruz reagents (Calpain-1 siRNA cat# sc-29885, and Calpain-2 siRNA, cat# sc-41459, Santa Cruz Biotechnology, San Diego, CA, USA) were used to knock down calpain-1 and calpain-2. For

(3) Calpain activity is negatively regulated by a KCTD7-Cullin-3 complex via non-degradative ubiquitinationCell discoveryMarch 24, 2023Sharma J, Mulherkar S, Chen UI, Xiong Y, Bajaj L, Cho BK, Goo YA, Leung HE, Tolias KF, Sardiello M.obtained from Santa-Cruz; KCTD7 (#sc-89656), Cullin-3 (#sc-35130), Calpain 1 (#sc-29885), and Calpain 2 (#sc-41459), Calpain reg. (#sc-29887). ON-TARGETplus Non-targeting Pool of siRNAs was purchased from Dharmacon

(4) hnRNPK-regulated LINC00263 promotes malignant phenotypes through miR-147a/CAPN2Cell death & diseaseMarch 17, 2021Lee WJ, Shin CH, Ji H, Jeong SD, Park MS, Won HH, Pandey PR, Tsitsipatis D, Gorospe M, Kim HH.shown in Supplementary Table 1). CAPN2-targeting siRNA was purchased from Santa Cruz Biotechnology (sc-41459: Santa Cruz, CA). Precursor miR-147a (pre-miR-147a: PM10020) and antisense miR-147a (anti-miR-147a:

(5) Calpain-2 participates in the process of calpain-1 inactivationBioscience reportsNovember 27, 2020Shinkai-Ouchi F, Shindo M, Doi N, Hata S, Ono Y.(Thermo Fischer Scientific) and subsequently cultured for 48 h. The siRNAs for CAPN1 (sc-29885), CAPN2 (sc-41459) and non-targeting siRNA (Control siRNA-A, sc-37007) were purchased from Santa Cruz Biotechnology [28–30].

(6) Anti-chlamydial activities of cell-permeable hydrophobic dipeptide-containing derivativesJournal of infection and chemotherapy : official journal of the Japan Society of ChemotherapyDecember 1, 2019Itoh R, Soejima T, Hiromatsu K.

(7) Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen speciesJournal of cellular physiologyAugust 1, 2019Lee CW, Chi MC, Chang TM, Liu JF.

(8) Use of a Mouse Model and Human Umbilical Vein Endothelial Cells to Investigate the Effect of Arsenic Exposure on Vascular Endothelial Function and the Associated Role of CalpainsEnvironmental health perspectivesJuly 1, 2019Cai Z, Zhang Y, Zhang Y, Miao X, Li S, Yang H, Ling Q, Hoffmann PR, Huang Z.were seeded in 6-well plates and transfected with CAPN-1 siRNA (sc-29885; Santa Cruz), CAPN2 siRNA (sc-41459; Santa Cruz), CAST siRNA (sc-29885; Santa Cruz), or control siRNA (sc-37007; Santa Cruz) using TransITsiQUEST

(9) Exploiting Honokiol-induced ER stress CHOP activation inhibits the growth and metastasis of melanoma by suppressing the MITF and β-catenin pathwaysCancer lettersFebruary 1, 2019Chiu CS, Tsai CH, Hsieh MS, Tsai SC, Jan YJ, Lin WY, Lai DW, Wu SM, Hsing HY, Arbiser JL, et al.

(10) Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transitionMolecular oncologyApril 1, 2015Liu SH, Lee WJ, Lai DW, Wu SM, Liu CY, Tien HR, Chiu CS, Peng YC, Jan YJ, Chao TH, et al.

(11) Hyperthermia induces apoptosis through endoplasmic reticulum and reactive oxygen species in human osteosarcoma cellsInternational journal of molecular sciencesSeptember 29, 2014Hou CH, Lin FL, Hou SM, Liu JF.

(12) Calpain 1 and -2 play opposite roles in cord formation of lymphatic endothelial cells via eNOS regulationHuman cellJune 1, 2012Prangsaengtong O, Senda K, Doki Y, Park JY, Jo M, Sakurai H, Shibahara N, Saiki I, Koizumi K.

(13) Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu micePloS oneJanuary 1, 2012Liu SH, Wang KB, Lan KH, Lee WJ, Pan HC, Wu SM, Peng YC, Chen YC, Shen CC, Cheng HC, et al.control were used and purchased from Santa Cruz Biotechnology (SHP-1 siRNA, sc-29478; Calpain II siRNA, sc-41459; Control siRNA, sc-37007). Immunohistochemistry The expressions of SHP-1 and p-STAT-3 proteins in

(14) Arsenic induces cell apoptosis in cultured osteoblasts through endoplasmic reticulum stressToxicology and applied pharmacologyDecember 1, 2009Tang CH, Chiu YC, Huang CF, Chen YW, Chen PC.

(15) Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growthPloS oneOctober 31, 2007Sheu ML, Liu SH, Lan KH.calpain-I, catalog no. sc-29885, a pool of 3 target-specific 20–25 nt siRNAs; calpain-II, catalog no. sc-41459, a target-specific 20–25 nt siRNA. The control siRNA (catalog no. sc-37007) is a non-targeting 20–25

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Calpain 2 siRNA (h)

Calpain 2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Calpain 2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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