Calpain 1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCalpain 1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29885
Gene Namecalpain 1, (mu/I) large subunit
Quantity10 µM
Specieshuman
NCBI Full Gene Namecalpain 1
NCBI Gene AliasesCANP, CANP1, CANPL1, SPG76, muCANP, muCL
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Neuroprotective Effects of Calpain Inhibition in Parkinson’s Disease: Insights from Cellular and Murine ModelsCellsAugust 24, 2025Vandana Zaman, Amy Gathings, Kelsey P. Drasites, Donald C. Shields, Narendra L. Banik, Azizul HaqueCalpain-2 in SV40 Human Microglia Cells Commercially available Santa Cruz reagents (Calpain-1 siRNA cat# sc-29885, and Calpain-2 siRNA, cat# sc-41459, Santa Cruz Biotechnology, San Diego, CA, USA) were used to knock

(2) Calpain activity is negatively regulated by a KCTD7-Cullin-3 complex via non-degradative ubiquitinationCell discoveryMarch 24, 2023Sharma J, Mulherkar S, Chen UI, Xiong Y, Bajaj L, Cho BK, Goo YA, Leung HE, Tolias KF, Sardiello M.Weller). siRNAs were obtained from Santa-Cruz; KCTD7 (#sc-89656), Cullin-3 (#sc-35130), Calpain 1 (#sc-29885), and Calpain 2 (#sc-41459), Calpain reg. (#sc-29887). ON-TARGETplus Non-targeting Pool of siRNAs was

(3) TRPC6 mediates high glucose-induced mitochondrial fission through activation of CDK5 in cultured human podocytesFrontiers in physiologyJanuary 1, 2022Yu H, Chen Y, Ma H, Wang Z, Zhang R, Jiao J.

(4) A Novel Topical Fluorescent Probe for Detection of GlioblastomaClinical cancer research : an official journal of the American Association for Cancer ResearchJuly 15, 2021Kitagawa Y, Tanaka S, Kamiya M, Kuriki Y, Yamamoto K, Shimizu T, Nejo T, Hana T, Matsuura R, Koike T, et al.

(5) Anti-chlamydial activities of cell-permeable hydrophobic dipeptide-containing derivativesJournal of infection and chemotherapy : official journal of the Japan Society of ChemotherapyDecember 1, 2019Itoh R, Soejima T, Hiromatsu K.

(6) Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variantThe Journal of biological chemistrySeptember 6, 2019Matos AM, Pinto FR, Barros P, Amaral MD, Pepperkok R, Matos P.

(7) Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen speciesJournal of cellular physiologyAugust 1, 2019Lee CW, Chi MC, Chang TM, Liu JF.

(8) Use of a Mouse Model and Human Umbilical Vein Endothelial Cells to Investigate the Effect of Arsenic Exposure on Vascular Endothelial Function and the Associated Role of CalpainsEnvironmental health perspectivesJuly 1, 2019Cai Z, Zhang Y, Zhang Y, Miao X, Li S, Yang H, Ling Q, Hoffmann PR, Huang Z.and siRNA HUVECs (2 × 105 per well) were seeded in 6-well plates and transfected with CAPN-1 siRNA (sc-29885; Santa Cruz), CAPN2 siRNA (sc-41459; Santa Cruz), CAST siRNA (sc-29885; Santa Cruz), or control siRNA

(9) Exploiting Honokiol-induced ER stress CHOP activation inhibits the growth and metastasis of melanoma by suppressing the MITF and β-catenin pathwaysCancer lettersFebruary 1, 2019Chiu CS, Tsai CH, Hsieh MS, Tsai SC, Jan YJ, Lin WY, Lai DW, Wu SM, Hsing HY, Arbiser JL, et al.

(10) Calpain-3-mediated regulation of the Na⁺-Ca²⁺ exchanger isoform 3Pflugers Archiv : European journal of physiologyFebruary 1, 2016Michel LY, Hoenderop JG, Bindels RJ.

(11) Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1Acta neuropathologica communicationsDecember 5, 2014Miners JS, Renfrew R, Swirski M, Love S.

(12) Hyperthermia induces apoptosis through endoplasmic reticulum and reactive oxygen species in human osteosarcoma cellsInternational journal of molecular sciencesSeptember 29, 2014Hou CH, Lin FL, Hou SM, Liu JF.

(13) Calpain 1 and -2 play opposite roles in cord formation of lymphatic endothelial cells via eNOS regulationHuman cellJune 1, 2012Prangsaengtong O, Senda K, Doki Y, Park JY, Jo M, Sakurai H, Shibahara N, Saiki I, Koizumi K.

(14) Arsenic induces cell apoptosis in cultured osteoblasts through endoplasmic reticulum stressToxicology and applied pharmacologyDecember 1, 2009Tang CH, Chiu YC, Huang CF, Chen YW, Chen PC.

(15) Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthaseJournal of cellular and molecular medicineSeptember 1, 2009Dong Y, Wu Y, Wu M, Wang S, Zhang J, Xie Z, Xu J, Song P, Wilson K, Zhao Z, et al.

(16) Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growthPloS oneOctober 31, 2007Sheu ML, Liu SH, Lan KH.(m-calpain) expressions in human cells were obtained from Santa Cruz Biotechnology: calpain-I, catalog no. sc-29885, a pool of 3 target-specific 20–25 nt siRNAs; calpain-II, catalog no. sc-41459, a target-specific 20–25

(17) The phosphorylation state of GluR1 subunits determines the susceptibility of AMPA receptors to calpain cleavageThe Journal of biological chemistryJune 1, 2007Yuen EY, Liu W, Yan Z.

(18) Calpain-2 participates in the process of calpain-1 inactivationBioscience reportsJanuary 1, 0001"Shinkai-Ouchi F, Shindo M, Doi N, Hata S, Ono Y."Lipofectamine RNAiMAX (Thermo Fischer Scientific) and subsequently cultured for 48 h. The siRNAs for CAPN1 (sc-29885), CAPN2 (sc-41459) and non-targeting siRNA (Control siRNA-A, sc-37007) were purchased from Santa Cruz Biotechnology

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Calpain 1 siRNA (h)

Calpain 1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Calpain 1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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