CXCR-4 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCXCR-4 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35422
Gene Namechemokine (C-X-C motif) receptor 4
Quantity10 µM
Speciesmouse
NCBI Full Gene Namechemokine (C-X-C motif) receptor 4
NCBI Gene AliasesCD184, CXC-R4, CXCR-4, Cmkar4, LESTR, PB-CKR, PBSF/SDF-1, Sdf1r, b2b220Clo
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injuryNeural Regeneration ResearchMay 1, 2025Mou Gao, Qin Dong, Dan Zou, Zhijun Yang, Lili Guo, Ruxiang Xu2. Loss-of-function study To knock down CXCR4 expression in iNSCs, we transfected iNSCs with CXCR4-specific siRNA (sc-35422, Santa Cruz Biotechnology, Santa Cruz, CA, USA) or control siRNA (sc-37007, Santa Cruz Biotechnology),

(2) Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injuryNeural Regen ResJune 26, 2024Mou Gao, Qin Dong, Dan Zou, Zhijun Yang, Lili Guo, Ruxiang Xu2. Loss-of-function study To knock down CXCR4 expression in iNSCs, we transfected iNSCs with CXCR4-specific siRNA (sc-35422, Santa Cruz Biotechnology, Santa Cruz, CA, USA) or control siRNA (sc-37007, Santa Cruz Biotechnology),

(3) Bone marrow hematopoiesis drives multiple sclerosis progressionCellJune 23, 2022Shi K, Li H, Chang T, He W, Kong Y, Qi C, Li R, Huang H, Zhu Z, Zheng P, et al.

(4) Duhuo Jisheng Decoction inhibits SDF-1-induced inflammation and matrix degradation in human degenerative nucleus pulposus cells in vitro through the CXCR4/NF-κB pathwayActa pharmacologica SinicaJune 1, 2018Liu ZC, Wang ZL, Huang CY, Fu ZJ, Liu Y, Wei ZC, Liu SG, Ma C, Shen JL, Duan DD.according to the manufacturer's protocol (Santa Cruz Biotechnology, Inc, Dallas, TX, USA; cat. no. Sc-35422). After transfection with 50 nmol/L CXCR4-siRNA for 72 h, the cultured cells were treated with or without

(5) Functional engineered mesenchymal stem cells with fibronectin-gold composite coated catheters for vascular tissue regenerationNanomedicine : nanotechnology, biology, and medicineApril 1, 2018Chen YW, Hsieh SC, Yang YC, Hsu SH, Kung ML, Lin PY, Hsieh HH, Lin CH, Tang CM, Hung HS.

(6) C-X-C Chemokine Receptor Type 4 Plays a Crucial Role in Mediating Oxidative Stress-Induced Podocyte InjuryAntioxidants & redox signalingAugust 20, 2017Mo H, Wu Q, Miao J, Luo C, Hong X, Wang Y, Tang L, Hou FF, Liu Y, Zhou L.transfected with flag-tagged CXCR4 expression vector (pCMV-CXCR4) or control and CXCR4-specific siRNA (sc-35422; Santa Cruz Biotechnology) as indicated by using Lipofectamine 2000 reagent (Invitrogen). Statistical

(7) Induced neural stem cells modulate microglia activation states via CXCL12/CXCR4 signalingBrain, behavior, and immunityJanuary 1, 2017Gao M, Dong Q, Yao H, Zhang Y, Yang Y, Dang Y, Zhang H, Yang Z, Xu M, Xu R.

(8) SDF‑1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF‑κB pathwayMolecular medicine reportsJuly 1, 2016Liu Z, Ma C, Shen J, Wang D, Hao J, Hu Z.interfering RNA (siRNA) targeting CXCR4 (Santa Cruz Biotechnology, Inc., Dallas, TX, USA; cat. no. sc-35422) according to the manufacturer's protocol using PepMute siRNA Transfection Reagent (SignaGen Laboratories,

(9) Tumor necrosis factor–related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotypeMol. Biol. CellSeptember 15, 2015Jing Gao, Dongsheng Wang, Dan Liu, Min Liu, Yehua Ge, Minghong Jiang, Yanxin Liu, Dexian Zhenginhibitors (GenePharma, Shanghai, China) were transfected to act as matched controls. HDAC1 siRNA (sc-35422, Santa Cruz Biotechnology, Santa Cruz, CA) and NF-κB p65 siRNA (sc-37007, Santa Cruz Biotechnology)

(10) Tumor necrosis factor–related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotypeMolecular Biology of the CellSeptember 15, 2015Jing Gao, Dongsheng Wang, Dan Liu, Min Liu, Yehua Ge, Minghong Jiang, Yanxin Liu, Dexian Zhenginhibitors (GenePharma, Shanghai, China) were transfected to act as matched controls. HDAC1 siRNA (sc-35422, Santa Cruz Biotechnology, Santa Cruz, CA) and NF-κB p65 siRNA (sc-37007, Santa Cruz Biotechnology)

(11) Stromal cell-derived factor-1 receptor CXCR4-overexpressing bone marrow mesenchymal stem cells accelerate wound healing by migrating into skin injury areasCellular reprogrammingJune 1, 2013Yang D, Sun S, Wang Z, Zhu P, Yang Z, Zhang B.

(12) The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesisClinical cancer research : an official journal of the American Association for Cancer ResearchOctober 1, 2012Zhuo W, Jia L, Song N, Lu XA, Ding Y, Wang X, Song X, Fu Y, Luo Y.

(13) Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathwayMolecular and cellular biologyAugust 1, 2012Asano S, Kitatani K, Taniguchi M, Hashimoto M, Zama K, Mitsutake S, Igarashi Y, Takeya H, Kigawa J, Hayashi A, et al.METHODS Antibodies and reagents. AMD3100 octahydrochloride hydrate (sc252367), fusin small interfering RNA (siRNA; sc-35422), and antibodies specific to extracellular signal-regulated kinase 2 (ERK2; C-14), actin (I-19; sc1616)

(14) Mesenchymal stromal cells may enhance metastasis of neuroblastoma via SDF-1/CXCR4 and SDF-1/CXCR7 signalingCancer lettersDecember 15, 2011Ma M, Ye JY, Deng R, Dee CM, Chan GC.

(15) CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2American journal of physiology. Lung cellular and molecular physiologyJanuary 1, 0001"Ghosh MC, Makena PS, Gorantla V, Sinclair SE, Waters CM."

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CXCR-4 siRNA (m)

CXCR-4 siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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CXCR-4 siRNA (m) from Santa Cruz Biotechnology, Inc.

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