Bim siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemBim siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29802
Gene NameBCL2-like 11 (apoptosis facilitator)
Quantity10 µM
Specieshuman
NCBI Full Gene NameBCL2 like 11
NCBI Gene AliasesBAM, BIM, BOD
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitorsCell death discoveryFebruary 4, 2023Qiu Y, Li Y, Chai M, Hua H, Wang R, Waxman S, Jing Y.Cell Signaling Technology, Inc. (Beverly, MA); and siRNAs for AXL (sc-29769), MCL1 (sc-35877) and BIM (sc-29802) were obtained from Santa Cruz Biotechnology (San Diego, CA). Cell lines MOLM-13 cells (with FLT3-ITD

(2) Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimeticsNature communicationsOctober 2, 2022Fraser CS, Spetz JKE, Qin X, Presser A, Choiniere J, Li C, Yu S, Blevins F, Hata AN, Miller JW, et al.separate 300 µL Opti-MEM Medium: Noxa, Bim, and control siRNA (Santa Cruz Biotechnologies, sc-37305, sc-29802, and sc-37007). The diluted siRNA solutions were then added to the diluted Lipofectamine solutions at

(3) Artesunate improves venetoclax plus cytarabine AML cell targeting by regulating the Noxa/Bim/Mcl-1/p-Chk1 axisCell death & diseaseApril 20, 2022Zhang J, Wang Y, Yin C, Gong P, Zhang Z, Zhao L, Waxman S, Jing Y.Noxa were obtained from Abcam, Inc. Bak (Ab-1) was obtained from Merck Millipore. NOXA(sc-37305), BIM(sc-29802), MCL1(sc-35877)siRNA, and a control siRNA were purchased from Santa Cruz Biotechnology, Inc. NOXA(s10708),

(4) Akt inhibitor augments anti-proliferative efficacy of a dual mTORC1/2 inhibitor by FOXO3a activation in p53 mutated hepatocarcinoma cellsCell death & diseaseNovember 10, 2021Patra T, Meyer K, Ray RB, Kanda T, Ray R.

(5) Severe cellular stress activates apoptosis independently of p53 in osteosarcomaCell death discoveryOctober 4, 2021Ho CJ, Ko HJ, Liao TS, Zheng XR, Chou PH, Wang LT, Lin RW, Chen CH, Wang C.knockdown by RNAi U2OS cells were grown up to 60% confluence. Bim siRNA (Santa Cruz Biotechnology, sc-29802, Dallas, TX, USA) or control siRNA (Santa Cruz Biotechnology, sc-37007) was pre-incubated in 500 μl

(6) MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting BimMolecular medicine reportsNovember 1, 2020Zhao Z, Zheng J, Ye Y, Zhao K, Wang R, Wang R.(siRNA) (cat no. sc-36869; Santa Cruz Biotechnology, Inc.), miR-25-3p inhibitor + Bim-siRNA (cat no. sc-29802; Santa Cruz Biotechnology, Inc.), miR-25-3p mimic (sense, 5′-CAUUGCACUUGUCUCGGUCUGA-3′ and anti-sense,

(7) Aspirin Induced Glioma Apoptosis through Noxa UpregulationInternational journal of molecular sciencesJune 13, 2020Chang CY, Pan PH, Li JR, Ou YC, Wang JD, Liao SL, Chen WY, Wang WY, Chen CJ.

(8) Dual targeting of BCL2 and MCL1 rescues myeloma cells resistant to BCL2 and MCL1 inhibitors associated with the formation of BAX/BAK hetero-complexesCell death & diseaseMay 5, 2020Seiller C, Maiga S, Touzeau C, Bellanger C, Kervoëlen C, Descamps G, Maillet L, Moreau P, Pellat-Deceunynck C, Gomez-Bougie P, et al.

(9) MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11Experimental and therapeutic medicineApril 1, 2020Zhang H, Xue S, Feng Y, Shen J, Zhao J.interfering (si)RNA (cat. no. sc‑36869; Santa Cruz Biotechnology, Inc.), 0.2 µM Bcl‑2L11‑siRNA (cat. no. sc‑29802; Santa Cruz Biotechnology, Inc.), 100 nM miR‑24‑3p inhibitor + 1 µM control‑siRNA, or 100 nM miR‑24‑3p

(10) Exosome miR-155 Derived from Gastric Carcinoma Promotes Angiogenesis by Targeting the c-MYB/VEGF Axis of Endothelial CellsMolecular therapy. Nucleic acidsMarch 6, 2020Deng T, Zhang H, Yang H, Wang H, Bai M, Sun W, Wang X, Si Y, Ning T, Zhang L, et al.(100 pmol) of miRNA mimics, inhibitors, small interfering RNAs (siRNAs) (Santa Cruz Biotechnology, sc-29802), or scrambled negative control RNA were used. The cells were harvested 24 h after transfection for

(11) MicroRNA-101-3p suppresses proliferation and migration in hepatocellular carcinoma by targeting the HGF/c-Met pathwayInvestigational new drugsFebruary 1, 2020Liu Y, Tan J, Ou S, Chen J, Chen L.

(12) Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignanciesCell death & diseaseDecember 4, 2019Kapoor I, Li Y, Sharma A, Zhu H, Bodo J, Xu W, Hsi ED, Hill BT, Almasan A.

(13) RETRACTED: miR-135b Delivered by Gastric Tumor Exosomes Inhibits FOXO1 Expression in Endothelial Cells and Promotes AngiogenesisMolecular therapy : the journal of the American Society of Gene TherapyOctober 2, 2019Bai M, Li J, Yang H, Zhang H, Zhou Z, Deng T, Zhu K, Ning T, Fan Q, Ying G, et al.

(14) Genipin Enhances the Therapeutic Effects of Oxaliplatin by Upregulating BIM in Colorectal CancerMolecular cancer therapeuticsApril 1, 2019Kim BR, Jeong YA, Jo MJ, Park SH, Na YJ, Kim JL, Jeong S, Yun HK, Kang S, Lee DH, et al.

(15) Dendrobine targeting JNK stress signaling to sensitize chemotoxicity of cisplatin against non-small cell lung cancer cells in vitro and in vivoPhytomedicine : international journal of phytotherapy and phytopharmacologyFebruary 1, 2019Song TH, Chen XX, Lee CK, Sze SC, Feng YB, Yang ZJ, Chen HY, Li ST, Zhang LY, Wei G, et al.

(16) LINC00261 functions as a competing endogenous RNA to regulate BCL2L11 expression by sponging miR-132-3p in endometriosisAmerican journal of translational researchJanuary 1, 2019Wang H, Sha L, Huang L, Yang S, Zhou Q, Luo X, Shi B.

(17) The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genesClinical epigeneticsNovember 8, 2018Alvarez MC, Maso V, Torello CO, Ferro KP, Saad STO.

(18) Inhibition of the NEDD8 conjugation pathway induces calcium-dependent compensatory activation of the pro-survival MEK/ERK pathway in acute lymphoblastic leukemiaOncotargetJanuary 19, 2018Zheng S, Leclerc GM, Li B, Swords RT, Barredo JC.

(19) Betulinic acid derivative B10 inhibits glioma cell proliferation through suppression of SIRT1, acetylation of FOXO3a and upregulation of Bim/PUMABiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieAugust 1, 2017Huo L, Bai X, Wang Y, Wang M.

(20) Cell-derived microvesicles mediate the delivery of miR-29a/c to suppress angiogenesis in gastric carcinomaCancer lettersJune 1, 2016Zhang H, Bai M, Deng T, Liu R, Wang X, Qu Y, Duan J, Zhang L, Ning T, Ge S, et al.

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Bim siRNA (h)

Bim siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Bim siRNA (h) from Santa Cruz Biotechnology, Inc.

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