Rock-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRock-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29473
Quantity10 µM
Gene NameRho-associated, coiled-coil containing protein kinase 1
Specieshuman
TypesiRNA/dsRNA
NCBI Full Gene NameRho associated coiled-coil containing protein kinase 1
NCBI Gene AliasesP160ROCK, ROCK-I

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Induction of adipocyte thermogenic program by Rho-associated coiled-coil containing kinase 2iScienceApril 17, 2026Haw-Chih Tai, Xiaoou Li, Christina J. Park, Altayeb Alshaikh, Brian Yu, Daiqing Chen, Phetcharat Chen, James K. Liaoinformation,N/A JNK1 siRNA (m),Santa Cruz Biotechnology,Cat# sc-29381 ROCK1 siRNA (h),Santa Cruz Biotechnology,Cat# sc-29473 ROCK2 siRNA (h),Santa Cruz Biotechnology,Cat#sc-29474 "Silencer Select Pre-Designed siRNA, mouse Foxo1",Thermo Fisher Scientific

(2) Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cellseLifeApril 19, 2023Julieta Martino, Sebastián Omar Siri, Nicolás Luis Calzetta, Natalia Soledad Paviolo, Cintia Garro, Maria F Pansa, Sofía Carbajosa, Aaron C Brown, José Luis Bocco, Israel Gloger, et al.manufacturer’s instructions. Unless otherwise stated, cells were transfected for a total of 48 hr. siROCK1 (#sc-29473 Santa Cruz Biotechnology) and siROCK2 (#sc-29474, Santa Cruz Biotechnology) were used at 100 nM. siEMI1

(3) Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cellsElifeApril 19, 2023Julieta Martino, Sebastián Omar Siri, Nicolás Luis Calzetta, Natalia Soledad Paviolo, Cintia Garro, Maria F Pansa, Sofía Carbajosa, Aaron C Brown, José Luis Bocco, Israel Gloger, et al.manufacturer’s instructions. Unless otherwise stated, cells were transfected for a total of 48 hr. siROCK1 (#sc-29473 Santa Cruz Biotechnology) and siROCK2 (#sc-29474, Santa Cruz Biotechnology) were used at 100 nM. siEMI1

(4) ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytesProceedings of the National Academy of Sciences of the United States of AmericaJanuary 17, 2023Tlili A, Pintard C, Hurtado-Nedelec M, Liu D, Marzaioli V, Thieblemont N, Dang PM, El-Benna J.penicillin/streptomycin. Cells were transfected with control (sc-37007) or ROCK2 siRNA (sc-29474) or ROCK1 (sc-29473) using reagents and protocol provided by Santa Cruz Biotechnology. After 48 h, the cells were washed

(5) The ROCK-ezrin signaling pathway mediates LPS-induced cytokine production in pulmonary alveolar epithelial cellsCell communication and signaling : CCSMay 12, 2022Ding N, Li P, Li H, Lei Y, Zhang Z.

(6) Numb inhibits migration and promotes proliferation of colon cancer cells via RhoA/ROCK signaling pathway repressionExperimental cell researchFebruary 15, 2022Yang Y, Li L, He H, Shi M, He L, Liang S, Qi J, Chen W.

(7) Roles of RAGE/ROCK1 Pathway in HMGB1-Induced Early Changes in Barrier Permeability of Human Pulmonary Microvascular Endothelial CellFrontiers in immunologyJanuary 1, 2021Zhao MJ, Jiang HR, Sun JW, Wang ZA, Hu B, Zhu CR, Yin XH, Chen MM, Ma XC, Zhao WD, et al.Phalloidin-iFluor 594 Conjugate was obtained from Absin Bioscience (Shanghai, China). ROCK1/2 siRNA (SC-29473/SC-29474), RAGE siRNA (SC-36374) and negative control siRNA were from Santa Cruz Biotechnology Co.,

(8) The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stromal /stem cells through interacting with the Notch1 proteinBMC cancerNovember 4, 2020Na T, Zhang K, Yuan BZ.

(9) Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial FissionCardiovascular drugs and therapyOctober 1, 2020Lu ZY, Qi J, Yang B, Cao HL, Wang RY, Wang X, Chi RF, Guo CL, Yang ZM, Liu HM, et al.

(10) Rock inhibition promotes Na(V)1.5 sodium channel-dependent SW620 colon cancer cell invasivenessScientific reportsAugust 7, 2020Poisson L, Lopez-Charcas O, Chadet S, Bon E, Lemoine R, Brisson L, Ouaissi M, Baron C, Besson P, Roger S, et al.

(11) Engineering blood outgrowth endothelial cells to optimize endothelial nitric oxide synthase and extracellular matrix production for coating of blood contacting surfacesActa biomaterialiaJune 1, 2020Yuan Y, Khan S, Stewart DJ, Courtman DW.

(12) ROCK1 promotes migration and invasion of non‑small‑cell lung cancer cells through the PTEN/PI3K/FAK pathwayInternational journal of oncologyOctober 1, 2019Hu C, Zhou H, Liu Y, Huang J, Liu W, Zhang Q, Tang Q, Sheng F, Li G, Zhang R.

(13) Oxygen-Glucose Deprivation/Reoxygenation Induces Human Brain Microvascular Endothelial Cell Hyperpermeability Via VE-Cadherin Internalization: Roles of RhoA/ROCK2Journal of molecular neuroscience : MNSeptember 1, 2019Chen J, Sun L, Ding GB, Chen L, Jiang L, Wang J, Wu J.

(14) ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial CellsInternational journal of molecular sciencesMarch 16, 2019Takeda Y, Matoba K, Kawanami D, Nagai Y, Akamine T, Ishizawa S, Kanazawa Y, Yokota T, Utsunomiya K.(Santa Cruz, CA, USA). Predesigned human small interfering RNA (siRNA) duplexes against ROCK1 (Cat# sc-29473), ROCK2 (Cat# sc-29474), MCP-1 (Cat# sc-43914), E-selectin (Cat# sc-29296) and control siRNA (Cat# sc-37007)

(15) Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cellsPloS oneJanuary 1, 2019Deng JT, Bhaidani S, Sutherland C, MacDonald JA, Walsh MP.in detail [33]. Human ROCK1 siRNA, purchased from Santa Cruz Biotechnology (Santa Cruz, CA; cat. no. sc29473), consists of three target-specific siRNAs (19–25 nucleotides). Human ZIPK siRNA, purchased from Ambion/Thermo Fisher Scientific

(16) Rho kinase inhibition maintains intestinal and vascular barrier function by upregulation of occludin in experimental necrotizing enterocolitisAmerican journal of physiology. Gastrointestinal and liver physiologyOctober 1, 2018Grothaus JS, Ares G, Yuan C, Wood DR, Hunter CJ.

(17) Unraveling endothelin-1 induced hypercontractility of human pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertensionPloS oneJanuary 1, 2018Wilson JL, Warburton R, Taylor L, Toksoz D, Hill N, Polgar P.

(18) miR-142-5p Improves Neural Differentiation and Proliferation of Adipose-Derived Stem CellsCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Yang L, Wang ZF, Wu H, Wang W.

(19) F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signallingNature communicationsJanuary 27, 2016Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, van Unen J, Pitter B, Huveneers S, Goedhart J, et al.concentration 50 nM), ICAM-1 sc-29354 (50 nM), PECAM-1 sc-29445 (50 nM), LARG sc-41800 (50 nM), Rock-1 (sc-29473) (50 nM), Rock-2b (sc-29474) (50 nM),and scrambled non-silencing siRNA were purchased from (Santa Cruz Biotechnology

(20) MiR-124 Promote Neurogenic Transdifferentiation of Adipose Derived Mesenchymal Stromal Cells Partly through RhoA/ROCK1, but Not ROCK2 Signaling PathwayPloS oneJanuary 1, 2016Wang Y, Wang D, Guo D.

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Rock-1 siRNA (h)

Rock-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Rock-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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