PTEN siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPTEN siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29459
Gene Namephosphatase and tensin homolog
Quantity10 µM
Specieshuman
NCBI Full Gene Namephosphatase and tensin homolog
NCBI Gene Aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta, TEP1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) PTEN/AKT signaling pathway related to hTERT downregulation and telomere shortening induced in Toxoplasma GRA16-expressing colorectal cancer cellsBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieSeptember 1, 2022Seo SH, Shin JH, Ham DW, Shin EH.

(2) PTEN: A novel target for vitamin D in melanomaThe Journal of steroid biochemistry and molecular biologyApril 1, 2022Shariev A, Painter N, Reeve VE, Haass NK, Rybchyn MS, Ince FA, Mason RS, Dixon KM.

(3) MicroRNA-221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTENExperimental and therapeutic medicineOctober 1, 2021Zhang L, Bu Z, Shen J, Shang L, Chen Y, Zhang P, Wang Y.sc-36869; Santa Cruz Biotechnology, Inc.) or 100 nM miR-221 inhibitor + 0.2 µM PTEN-siRNA (cat. no. sc-29459; Santa Cruz Biotechnology, Inc.) using Lipofectamine 3000 reagent, according to the manufacturer's instructions.

(4) Osthole resensitizes CD133(+) hepatocellular carcinoma cells to cisplatin treatment via PTEN/AKT pathwayAgingJuly 16, 2020Ye J, Sun D, Yu Y, Yu J.

(5) PTEN and PHLPP crosstalk in cancer cells and in TGFβ-activated stem cellsBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJuly 1, 2020Ghalali A, Ye ZW, Högberg J, Stenius U.

(6) Protein phosphatase Mg(2+) /Mn(2+) dependent-1A and PTEN deregulation in renal fibrosis: Novel mechanisms and co-dependency of expressionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2020Tang J, Goldschmeding R, Samarakoon R, Higgins PJ.

(7) Differential Dependency of Human Pancreatic Cancer Cells on Targeting PTEN via PLK 1 ExpressionCancersJanuary 23, 2020Lee J, Lee J, Sim W, Kim JH.reagents (Invitrogen, Carlsbad, CA, USA), as previously reported [40]. Oligonucleotides specific for PTEN (sc-29459 and 5728-1) and PLK1 (sc-36277 and 5347-1) have been obtained from Santa Cruz Biotechnology (Santa Cruz,

(8) Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignanciesCell death & diseaseDecember 4, 2019Kapoor I, Li Y, Sharma A, Zhu H, Bodo J, Xu W, Hsi ED, Hill BT, Almasan A.

(9) SHCBP1 regulates apoptosis in lung cancer cells through phosphatase and tensin homologOncology lettersAugust 1, 2019Wang F, Li Y, Zhang Z, Wang J, Wang J.from Abbexa Ltd. (cat. no. abx933286) and PTEN siRNA from Santa Cruz Biotechnology, Inc. (cat. no. sc-29459) Shanghai GenePharma Co., Ltd. synthesized the negative control (NC) siRNA. The siRNA-NC sequence was

(10) Aberrant expression and mechanism of miR-130b-3p/phosphatase and tensin homolog in nephroblastoma in childrenExperimental and therapeutic medicineAugust 1, 2019Hu Y, Yan J.control-siRNA (cat. no. Sc-36869; Santa Cruz Biotechnology, Inc., Dallas, TX, USA), 2 µl PTEN-siRNA (cat. no. Sc-29459; Santa Cruz Biotechnology, Inc.), 100 nM miR-130b-3p inhibitor + 2 µl control-siRNA or 100 nM miR-130b-3p

(11) PTEN Inhibition Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury Through PTEN/E2F1/β-Catenin PathwayFrontiers in molecular neuroscienceJanuary 1, 2019Zhao D, Qin XP, Chen SF, Liao XY, Cheng J, Liu R, Lei Y, Zhang ZF, Wan Q.by Genechem (Shanghai, China, GOSE91553) as in our previous study (Chen et al., 2016). PTEN siRNA (sc-29459), E2F1 siRNA (sc-29297), and control siRNA (sc-44236) were purchased from Santa Cruz Biotechnology.

(12) Involvement of Phosphatase and Tensin Homolog in Cyclin-Dependent Kinase 4/6 Inhibitor-Induced Blockade of GlioblastomaFrontiers in pharmacologyJanuary 1, 2019Liu S, Yuan D, Li Y, Qi Q, Guo B, Yang S, Zhou J, Xu L, Chen T, Yang C, et al.ERK (CA, Cat# 39194) (Robinson et al., 1998), and PTEN (#78776) were from Addgene. PTEN siRNA (Cat# sc-29459) and control siRNA (Cat# sc-36369) were purchased from Santa Cruz. All chemicals and reagents not described

(13) Doxorubicin resistance induces IL6 activation in the colon cancer cell line LS180Oncology lettersNovember 1, 2018Li XY, Liao XF, Wang HB, Zhang J.

(14) Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survivalOncogeneAugust 1, 2018Baker A, Wyatt D, Bocchetta M, Li J, Filipovic A, Green A, Peiffer DS, Fuqua S, Miele L, Albain KS, et al.(Cat. sc-36095, Santa Cruz), Notch-1 #2 (Cat. HSS107248, Dharmacon, Lafayette, CO), and/or PTEN (Cat. sc-29459, A, B, C, Santa Cruz) siRNA with RNAiMax (Cat. 13778150, Thermo Fisher, Waltham, MA) at a 1:1 ratio

(15) ERK 1/2 Activation Mediates the Neuroprotective Effect of BpV(pic) in Focal Cerebral Ischemia-Reperfusion InjuryNeurochemical researchJuly 1, 2018Liu R, Tang JC, Pan MX, Zhuang Y, Zhang Y, Liao HB, Zhao D, Lei Y, Lei RX, Wang S, et al.

(16) MicroRNA-130b targets PTEN to induce resistance to cisplatin in lung cancer cells by activating Wnt/β-catenin pathwayCell biochemistry and functionJune 1, 2018Zhang Q, Zhang B, Sun L, Yan Q, Zhang Y, Zhang Z, Su Y, Wang C.

(17) Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δEBioMedicineMay 1, 2018Zhou T, Luo M, Cai W, Zhou S, Feng D, Xu C, Wang H.

(18) The phosphoinositide 3-kinase pathway and glycogen synthase kinase-3 positively regulate the activity of metal-responsive transcription factor-1 in response to zinc ionsBiochemistry and cell biology = Biochimie et biologie cellulaireApril 30, 2018Andéol Y, Bonneau J, M Gagné L, Jacquet K, Rivest V, Huot MÉ, Séguin C.rapamycin, LY2090314, and CHIR99021 were purchased from Selleckchem (Houston, Texas, USA), whereas PTEN (sc-29459) and negative control (sc37007) siRNAs were from Santa Cruz Biotechnology, Inc. (Dallas, Tex.). All

(19) Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cellsOncotargetApril 13, 2018Kim EJ, Kang GJ, Kang JI, Boo HJ, Hyun JW, Koh YS, Chang WY, Kim YR, Kwon JM, Maeng YH, et al.visualized using an FV500 confocal microscope (Olympus, Tokyo, Japan). Gene silencing PTEN siRNA (sc-29459) and AKT1 siRNA (sc-29195) were purchased from Santa Cruz Biotechnology. SNU-C5/WT cells were transfected

(20) Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cellsThe ProstateApril 1, 2018Kimbrough-Allah MN, Millena AC, Khan SA.10759), and pcDNA3 GFP (plasmid #20738) were obtained from Addgene (Cambridge, MA). Human PTEN siRNA (sc-29459) and control non-silencing siRNA (sc-37007) were purchased from Santa Cruz Biotechnology (Dallas, TX).

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PTEN siRNA (h)

PTEN siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PTEN siRNA (h) from Santa Cruz Biotechnology, Inc.

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