Integrin α3 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIntegrin α3 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-35684
Gene Nameintegrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Quantity10 µM
Specieshuman
NCBI Full Gene Nameintegrin subunit alpha 3
NCBI Gene AliasesCD49C, FRP-2, GAP-B3, GAPB3, ILNEB, JEB7, MSK18, VCA-2, VL3A, VLA3a
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Phenotypic discovery and therapeutic evaluation of an ITGA3B1-targeting antibody-drug conjugate for bladder cancerSci AdvJanuary 1, 2026Junghyeon Lee, Hyeryeon Jung, Eunhee G. Kim, Jinsung Ahn, Michael C. Haffner, Peter S. Nelson, Kwang Pyo Kim, John K. Lee, Eugene C. Yi, Kristine M. Kim105) were seeded in six-well plates and incubated overnight. Target-specific siRNAs against ITGA3 (sc-35684) and ITGB1 (sc-35674), along with a nontargeting control siRNA (sc-37007), were obtained from Santa Cruz Biotechnology

(2) Control cell migration by engineering integrin ligand assemblyNature communicationsAugust 25, 2022Hu X, Roy SR, Jin C, Li G, Zhang Q, Asano N, Asahina S, Kajiwara T, Takahara A, Feng B, et al.

(3) Magnesium cationic cue enriched interfacial tissue microenvironment nurtures the osseointegration of gamma-irradiated allograft boneBioactive materialsApril 1, 2022Wang W, Shen J, Meng Y, Ye M, Lin S, Zhao Q, Wang L, Cheung KMC, Wu S, Zheng Y, et al.

(4) Targeting of the COX-2/PGE2 axis enhances the antitumor activity of T7 peptide in vitro and in vivoDrug deliveryDecember 1, 2021Yang J, Zhong J, Zhou M, Zhou Y, Xiu P, Liu F, Wang F, Li Z, Tang Y, Chen Y, et al.Human VEGF ELISA Kit was purchased from Abcam (Cambridge, UK). Integrin β3 siRNA (sc-29375), integrin α3 siRNA (sc-35684), COX-2 siRNA (sc-29729), negative control siRNA (NC siRNA, sc-37007), and siRNA transfection reagent

(5) Blockade of integrin α3 attenuates human pancreatic cancer via inhibition of EGFR signallingScientific reportsFebruary 26, 2019Lee J, Lee J, Choi C, Kim JH.Effectene reagent (Qiagen, Hilden, Germany) as described previously35. Oligonucleotides specific for ITGα3 (sc-35684 for #1 and SDH-1002 for #2) and scrambled control (sc-37007) were obtained from Santa Cruz Biotechnology

(6) Aspergillus fumigatus CalA binds to integrin α₅β₁ and mediates host cell invasionNature microbiologyNovember 14, 2016Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG.Santa Cruz Biotechnology), integrin α5 siRNA (sc-29372; Santa Cruz Biotechnology), α3 integrin siRNA (sc-35684; Santa Cruz Biotechnology), or random control siRNA (Qiagen) using Lipofectamine 2000 (Invitrogen).

(7) Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cellsOncotargetDecember 15, 2015Kim HIe, Lee HS, Kim TH, Lee JS, Lee ST, Lee SJ.A549 cells A549 cells were transfected with various siRNAs [PKAα cat siRNA (sc-36240), 80 nM; α3-integrin siRNA (sc-35684), 50 nM; c-Src siRNA (sc-29228), 50 nM; control siRNA (sc-37007), 50 nM] (Santa Cruz Biotechnology)

(8) Antagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathwayBloodDecember 6, 2012Kim SH, Cho YR, Kim HJ, Oh JS, Ahn EK, Ko HJ, Hwang BJ, Lee SJ, Cho Y, Kim YK, et al.Santa Cruz Biotechnology. hMVECs in gelatin-coated 100-mm dishes were transfected with siRNA (integrin ␣3 siRNA (sc-35684), 50nM; Shp-1 siRNA (sc29478), 50nM; Shp-2 siRNA (sc-36488), 50nM; control siRNA (sc-37007), 50nM) using

(9) TIMP-2 disrupts FGF-2-induced downstream signaling pathwaysMicrovascular researchNovember 1, 2008Seo DW, Kim SH, Eom SH, Yoon HJ, Cho YR, Kim PH, Kim YK, Han JW, Diaz T, Wei BY, et al.Subconfluent hMVECs in gelatin-coated 100 mm dishes were transfected with siRNA (integrin α3 siRNA (sc-35684): 50 nM; control siRNA (sc-37007): 50 nM) using Lipofectamine RNAiMAX (Invitrogen) and OPTI-MEM I reduced serum medium

(10) SIKVAV, a laminin alpha1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathwayThe American journal of pathologyJuly 1, 2007Freitas VM, Vilas-Boas VF, Pimenta DC, Loureiro V, Juliano MA, Carvalho MR, Pinheiro JJ, Camargo AC, Moriscot AS, Hoffman MP, et al.

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