Ref-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRef-1 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29470
Gene NameAPEX nuclease (multifunctional DNA repair enzyme) 1
Quantity10 µM
Specieshuman
NCBI Full Gene Nameapurinic/apyrimidinic endodeoxyribonuclease 1
NCBI Gene AliasesAPE, APE1, APEN, APEX, APX, HAP1, REF1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Enhancing the antitumor efficacy using a combination of FGFR4 Inhibitor (H3B-6527) and oxaliplatin in gastric cancerNeoplasiaJanuary 1, 2026Nadeem Bhat, Mohammed Soutto, Zheng Chen, Marwah Al-Mathkour, Silvia Giordano, Mohammed Chwihne, Melanie Genoula, Farah Ballout, Shoumin Zhu, Oliver G McDonald, et al.NC, USA). Transfection Scrambled siRNA was purchased from Santa Cruz Biotechnology (CA, USA; Cat. #sc-29470). FGFR4 siRNAs was obtained from ThermoFisher Scientific (Cat. #4390825). For transient FGFR4 knockdown,

(2) Targeting SMAD3 improves response to oxaliplatin in esophageal adenocarcinoma models by impeding DNA repairClin Cancer ResMay 15, 2024Farah Ballout, Heng Lu, Nadeem Bhat, Lei Chen, Dunfa Peng, Zheng Chen, Steven Chen, Xiaodian Sun, Silvia Giordano, Simona Corso, et al.lentivirus infection Scrambled siRNA was purchased from Santa Cruz Biotechnology (RRID:SCR_008987, CA, USA; sc-29470). SMAD3 siRNAs were obtained from Dharmacon (L-020067–00-0005; Lafayette, CO, USA) and Thermo Fisher

(3) APE-1/Ref-1 Inhibition Blocks Malignant Pleural Mesothelioma Cell Proliferation and Migration: Crosstalk between Oxidative Stress and Epithelial Mesenchymal Transition (EMT) in Driving Carcinogenesis and MetastasisInternational journal of molecular sciencesAugust 8, 2023Ramundo V, Zanirato G, Palazzo ML, Riganti C, Aldieri E.below. 4.3. siRNA Ref-1 siRNA targeting Ref-1 (siRef-1) was purchased by Santa Cruz Biotecnology (sc-29470; Santa Cruz Biotechnology, Santa Cruz, CA, USA). The cells were seeded into 6-well plates at a density

(4) APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett's-associated esophageal adenocarcinomasJournal of experimental & clinical cancer research : CRSeptember 1, 2022Ballout F, Lu H, Chen L, Sriramajayam K, Que J, Meng Z, Wang TC, Giordano S, Zaika A, McDonald O, et al.Biologicals (NBP1-49,581, Centennial, CO, USA). Transfection and lentivirus infection Scrambled si-RNA (sc-29470) was purchased from Santa Cruz Biotechnology. APE1 si-RNA (L-010237–00-0005) was obtained from Dharmacon

(5) Downregulation of APE1 potentiates breast cancer cells to olaparib by inhibiting PARP-1 expressionBreast cancer research and treatmentJuly 1, 2019Ma X, Dang C, Min W, Diao Y, Hui W, Wang X, Dai Z, Wang X, Kang H.

(6) Exposure of Barrett's and esophageal adenocarcinoma cells to bile acids activates EGFR-STAT3 signaling axis via induction of APE1OncogeneNovember 1, 2018Bhat AA, Lu H, Soutto M, Capobianco A, Rai P, Zaika A, El-Rifai W.VectorBuilder Inc. (Santa Clara, CA, USA) and then used to transduce OE33 and CPB cells. Control siRNA (sc-29470) and APE1 siRNA (sc-29470) were obtained from Santa Cruz Biotechnology. 3D organotypic cultures of

(7) GFRA1 promotes cisplatin-induced chemoresistance in osteosarcoma by inducing autophagyAutophagyJanuary 2, 2017Kim M, Jung JY, Choi S, Lee H, Morales LD, Koh JT, Kim SH, Choi YD, Choi C, Slaga TJ, et al.

(8) APE1/REF-1 down-regulation enhances the cytotoxic effects of temozolomide in a resistant glioblastoma cell lineMutation research. Genetic toxicology and environmental mutagenesisNovember 1, 2015Montaldi AP, Godoy PR, Sakamoto-Hojo ET.

(9) Inhibition of ref-1 stimulates the production of reactive oxygen species and induces differentiation in adult cardiac stem cellsAntioxidants & redox signalingMarch 1, 2009Gurusamy N, Mukherjee S, Lekli I, Bearzi C, Bardelli S, Das DK.

(10) Intracellular signaling pathways regulating radioresistance of human prostate carcinoma cellsProteomicsNovember 1, 2008Skvortsova I, Skvortsov S, Stasyk T, Raju U, Popper BA, Schiestl B, von Guggenberg E, Neher A, Bonn GK, Huber LA, et al.

(11) APEX1 regulation of aldosterone synthase gene transcription is disrupted by a common polymorphism in humansCirculation researchJanuary 1, 0001"McManus F, Sands W, Diver L, MacKenzie SM, Fraser R, Davies E, Connell JM."II (1⫻10⫺7M). For siRNA experiments, cells were transfected with siRNA targeted to APEX1/Ref1 (human ref1, sc-29470, Santa Cruz, CA) or with a scrambled control siRNA (control A, sc-37007, Santa Cruz). Each experiment

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Ref-1 siRNA (h)

Ref-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Ref-1 siRNA (h) from Santa Cruz Biotechnology, Inc.

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