Atm siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemAtm siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29761
Gene Nameataxia telangiectasia mutated
Quantity10 µM
Specieshuman
NCBI Full Gene NameATM serine/threonine kinase
NCBI Gene AliasesAT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Ataxia-Telangiectasia Mutated Is Involved in Autolysosome FormationBiomolecules & therapeuticsSeptember 1, 2023Hwang M, Jun DW, Song BR, Shim H, Lee CH, Kim S.fetal bovine serum (FBS; Corning) at 37°C in a humidified atmosphere with 5% CO2. siRNAs targeting ATM (sc-29761) and the negative control siRNA were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

(2) Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb1Drug and chemical toxicologyNovember 1, 2022Liu Y, Li J, Ding H, Ge D, Wang J, Xu C.

(3) Non-enzymatic function of WRN RECQL helicase regulates removal of topoisomerase-I-DNA covalent complexes and triggers NF-κB signaling in cancerAging cellJune 1, 2022Gupta P, Majumdar AG, Patro BS.

(4) Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiencyMolecular cellApril 1, 2021Lee JH, Ryu SW, Ender NA, Paull TT.

(5) Inhibition of non-homologous end joining of gamma ray-induced DNA double-strand breaks by cAMP signaling in lung cancer cellsScientific reportsSeptember 2, 2020Noh SE, Juhnn YS.

(6) PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancerScience advancesOctober 1, 2019Li Q, Hao Q, Cao W, Li J, Wu K, Elshimali Y, Zhu D, Chen QH, Chen G, Pollack JR, et al.

(7) Retrograde Regulation by the Viral Protein Kinase Epigenetically Sustains the Epstein-Barr Virus Latency-to-Lytic Switch To Augment Virus ProductionJournal of virologySeptember 1, 2019Li X, Kozlov SV, El-Guindy A, Bhaduri-McIntosh S.siRNAs targeting human ATM transcripts and scrambled siRNA were purchased from Santa Cruz Biotechnology (sc-29761). A previously validated siRNA targeting BGLF4 transcript (25) was synthesized by Dharmacon. HH514-16

(8) Interleukin 6-triggered ataxia-telangiectasia mutated kinase activation facilitates epithelial-to-mesenchymal transition in lung cancer by upregulating vimentin expressionExperimental cell researchAugust 15, 2019Jiang YN, Ni XY, Yan HQ, Shi L, Lu NN, Wang YN, Li Q, Gao FG.

(9) Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcriptionNucleic acids researchJuly 26, 2019Velichko AK, Petrova NV, Luzhin AV, Strelkova OS, Ovsyannikova N, Kireev II, Petrova NV, Razin SV, Kantidze OL.manufacturer's instructions. The cells were transfected with 200 nM ATM siRNA (Santa Cruz Biotechnology, #sc-29761), 50 nM ATR siRNA (Santa Cruz Biotechnology, # sc-29763), 100 nM DNA-PKcs (PRKDC; Santa Cruz Biotechnology,

(10) MiR-203a-3p regulates the biological behaviors of ovarian cancer cells through mediating the Akt/GSK-3β/Snail signaling pathway by targeting ATMJournal of ovarian researchJuly 5, 2019Liu HY, Zhang YY, Zhu BL, Feng FZ, Zhang HT, Yan H, Zhou B.

(11) PARP inhibition induces Akt-mediated cytoprotective effects through the formation of a mitochondria-targeted phospho-ATM-NEMO-Akt-mTOR signalosomeBiochemical pharmacologyApril 1, 2019Tapodi A, Bognar Z, Szabo C, Gallyas F, Sumegi B, Hocsak E.

(12) Cell type-dependent bimodal p53 activation engenders a dynamic mechanism of chemoresistanceScience advancesDecember 1, 2018Yang R, Huang B, Zhu Y, Li Y, Liu F, Shi J.[School of Biomedical Sciences, University of Hong Kong (40)], and siATM-2 (used at 60 nM in U-2 OS; #sc-29761, Santa Cruz Biotechnology). Dharmacon On-Target plus siControl (#D-001810-01) was used as a nontargeting

(13) Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacityScience signalingJuly 10, 2018Zhang Y, Lee JH, Paull TT, Gehrke S, D'Alessandro A, Dou Q, Gladyshev VN, Schroeder EA, Steyl SK, Christian BE, et al.

(14) ATM directs DNA damage responses and proteostasis via genetically separable pathwaysScience signalingJanuary 9, 2018Lee JH, Mand MR, Kao CH, Zhou Y, Ryu SW, Richards AL, Coon JJ, Paull TT.

(15) ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?CarcinogenesisDecember 7, 2017Zheng H, Högberg J, Stenius U.

(16) Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cellsPLoS pathogensMarch 1, 2017Li X, Burton EM, Bhaduri-McIntosh S.transcripts and scrambled/non-targeting siRNA were purchased from Santa Cruz Biotechnology (sc-38550, sc-29761 and sc-37007) and Dharmacon (D-001206-13-05 and M-005046-01) and reconstituted with nuclease free water.

(17) Distinct biological effects of low-dose radiation on normal and cancerous human lung cells are mediated by ATM signalingOncotargetNovember 1, 2016Yang G, Yu D, Li W, Zhao Y, Wen X, Liang X, Zhang X, Zhou L, Hu J, Niu C, et al.early change of mitochondrial membrane potential. siRNA transfection The sequence of human ATM siRNA (sc-29761) and control siRNA (sc-37007) were from Santa Cruz Biotechnology. HBE and A549 cells were seeded in

(18) Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cellsCancer biology & therapyNovember 1, 2016Rahal ON, Fatfat M, Hankache C, Osman B, Khalife H, Machaca K, Muhtasib HG.

(19) Ataxia-telangiectasia mutated activation mediates tumor necrosis factor-alpha induced MMP-13 up-regulation and metastasis in lung cancer cellsOncotargetSeptember 20, 2016Yan HQ, Zhang D, Shi YY, You X, Shi L, Li Q, Gao FG.controls were purchased from Santa Cruz Biotechnology. They are TNF-α siRNA (sc-37216), ATM siRNA (sc-29761), NFκB p65 siRNA (sc-29410), hMMP3 siRNA (sc-29399), hMMP9 siRNA (sc-29400), hMMP13 siRNA (sc-41559) and

(20) MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancerCancer immunology, immunotherapy : CIIMay 1, 2016Okita R, Yukawa T, Nojima Y, Maeda A, Saisho S, Shimizu K, Nakata M.

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Atm siRNA (h)

Atm siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Atm siRNA (h) from Santa Cruz Biotechnology, Inc.

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