G9a siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemG9a siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-43777
Gene Nameeuchromatic histone-lysine N-methyltransferase 2
Quantity10 µM
TypesiRNA/dsRNA
NCBI Gene AliasesBAT8, C6orf30, G9A, GAT8, KMT1C, NG36
NCBI Full Gene Nameeuchromatic histone lysine methyltransferase 2
Specieshuman

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cellsActa pharmacologica SinicaMarch 1, 2022Kim TW.

(2) BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cellsInvestigational new drugsJune 1, 2021Li Q, Wang L, Ji D, Bao X, Tan G, Liang X, Deng P, Pi H, Lu Y, Chen C, et al.

(3) EHMT2 epigenetically suppresses Wnt signaling and is a potential target in embryonal rhabdomyosarcomaeLifeNovember 30, 2020Pal A, Leung JY, Ang GCK, Rao VK, Pignata L, Lim HJ, Hebrard M, Chang KT, Lee VK, Guccione E, et al.

(4) Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory SignalingArteriosclerosis, thrombosis, and vascular biologyNovember 1, 2019Harman JL, Dobnikar L, Chappell J, Stokell BG, Dalby A, Foote K, Finigan A, Freire-Pritchett P, Taylor AL, Worssam MD, et al.passage 4. VSMCs were treated with UNC0638 (UNC; 1 μM Tocris), small interfering RNA targeting G9A (sc-43777, Santa Cruz), control small interfering RNA (sc-37007, Santa Cruz), SP600125 (10 μM, Abcam), human recombinant

(5) Trans-suppression of host CDH3 and LOXL4 genes during Cryptosporidium parvum infection involves nuclear delivery of parasite Cdg7_FLc_1000 RNAInternational journal for parasitologyMay 1, 2018Ming Z, Gong AY, Wang Y, Zhang XT, Li M, Li Y, Pang J, Dong S, Strauss-Soukup JK, Chen XM.

(6) Targeting EHMT2 reverses EGFR-TKI resistance in NSCLC by epigenetically regulating the PTEN/AKT signaling pathwayCell death & diseaseJanuary 26, 2018Wang L, Dong X, Ren Y, Luo J, Liu P, Su D, Yang X.

(7) Methyltransferase G9a promotes cervical cancer angiogenesis and decreases patient survivalOncotargetSeptember 22, 2017Chen RJ, Shun CT, Yen ML, Chou CH, Lin MC.Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). The targeted siRNA for G9a and control siRNA were sc-43777 and sc-37007, respectively. Cervical cancer cell lines were transfected with siRNA using the siRNA Transfection

(8) Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9aToxicology and applied pharmacologyAugust 1, 2016Zhang X, Wu J, Choiniere J, Yang Z, Huang Y, Bennett J, Wang L.group), 48h 10 µM BRD4770 (BRD group) and 10 µM BRD4770 plus 1.0 µM NaAsO2 (BRD + As group). G9a siRNA (sc-43777) was purchased from Santa Cruz. Mouse study and treatment Wild-type C57BL/6 mice were purchased from

(9) Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κBOncotargetJune 28, 2016Park SE, Yi HJ, Suh N, Park YY, Koh JY, Jeong SY, Cho DH, Kim CS, Hwang JJ.overexpression of EHMT2, and transfection Control non-targeting siRNA (sc-37007) and EHMT2 siRNA (sc-43777) were obtained from Santa Cruz. The pcDNA3 (empty vector, MOCK) and pcDNA3-Flag-EHMT2 (FLAG-EHMT2) constructs

(10) H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil ChemoresistanceJournal of immunology (Baltimore, Md. : 1950)August 15, 2015Paschall AV, Yang D, Lu C, Choi JH, Li X, Liu F, Figueroa M, Oberlies NH, Pearce C, Bollag WB, et al.G9a-, SUV39H1-, and SUV39H2-specific siRNAs were obtained from Santa Cruz Biotechnology (catalog nos. sc-43777, sc-38463, and sc106822). SW620-5FU-R cells were transfected as described above. Cells were then analyzed

(11) Leptin-STAT3-G9a Signaling Promotes Obesity-Mediated Breast Cancer ProgressionCancer researchJune 1, 2015Chang CC, Wu MJ, Yang JY, Camarillo IG, Chang CJ.

(12) The visualization of large organized chromatin domains enriched in the H3K9me2 mark within a single chromosome in a single cellEpigeneticsNovember 1, 2014Chen X, Yammine S, Shi C, Tark-Dame M, Göndör A, Ohlsson R.

(13) Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatmentPloS oneJanuary 1, 2014Loh SW, Ng WL, Yeo KS, Lim YY, Ea CK.

(14) BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species productionAutophagyDecember 1, 2013Kim Y, Kim YS, Kim DE, Lee JS, Song JH, Kim HG, Cho DH, Jeong SY, Jin DH, Jang SJ, et al.

(15) Suppression and recovery of BRCA1-mediated transcription by HP1γ via modulation of promoter occupancyNucleic acids researchDecember 1, 2012Choi JD, Park MA, Lee JS.the siRNAs for RIZ1, SETDB1, G9a, G9a-like protein-1 (GLP-1) and the control (sc-106513, sc-45659, sc-43777, sc-62261 and sc-37007, respectively; Santa Cruz Biotechnology, Santa Cruz, CA, USA). Pull-down analysis His–HP1γ

(16) Neurotrophin-mediated degradation of histone methyltransferase by S-nitrosylation cascade regulates neuronal differentiationProceedings of the National Academy of Sciences of the United States of AmericaDecember 13, 2011Sen N, Snyder SH.

(17) Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locusPloS oneOctober 29, 2010Li Q, Wang X, Lu Z, Zhang B, Guan Z, Liu Z, Zhong Q, Gu L, Zhou J, Zhu B, et al.assay The knockdown of Suv39h2 (sc-106822; Santa Cruz) and Suv39h1 (sc-38463; Santa Cruz) and G9a (sc-43777; Santa Cruz) was accomplished with siRNA duplex transiently. Scramble siRNA (5′-uucuc cgaac guguc acgu-3′)

(18) The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repressionNucleic acids researchJanuary 1, 2010Yang YJ, Han JW, Youn HD, Cho EJ.

(19) The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin toleranceThe Journal of biological chemistryOctober 9, 2009Chen X, El Gazzar M, Yoza BK, McCall CE.

(20) G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin toleranceThe Journal of biological chemistryNovember 21, 2008El Gazzar M, Yoza BK, Chen X, Hu J, Hawkins GA, McCall CE.

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G9a siRNA (h)

G9a siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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G9a siRNA (h) from Santa Cruz Biotechnology, Inc.

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