ATG5 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemATG5 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-41445
Gene Nameautophagy-related 5 (yeast)
Quantity10 µM
Specieshuman
NCBI Full Gene Nameautophagy related 5
NCBI Gene AliasesAPG5, APG5-LIKE, APG5L, ASP, SCAR25, hAPG5
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Formyl Peptide Receptor-2-Suppressed Autophagy Promotes the Migration and Invasion of Human Glioblastoma Cells Through PI3K/Akt SignalingJ Neuroimmune PharmacolMarch 9, 2026Zhenzhao Luo, Deyong Kong, Guangjian Qi, Chao Zheng, Wushi Zhao, Zhongxin Lucorresponding control cell lines, were established. siRNAs targeting BECN1 (sc-29797; Santa Cruz, USA), ATG5 (sc-41445; Santa Cruz, USA), control siRNA (sc-37007; Santa Cruz, USA) or SQSTM1 (sc-29679; Santa Cruz, USA) were

(2) Notoginsenoside R1 mitigates UVB-induced skin sunburn injury through modulation of N4-acetylcytidine and autophagyChin MedDecember 18, 2025Shuyun Liang, Xiaokang Liu, Yuting Yang, Fangyuan Zhang, Xiaobo Sun, Tong Zhang, Dean Guo, Jiyu Gong, Zizhao Yangregulation. siRNA transfection The following siRNAs were used: siRNA-ATG7 (sc-41447), siRNA-ATG5 (sc-41445), siRNA-NAT10 (sc-62660), and negative control siRNA (sc-37007), all purchased from Santa Cruz Biotechnology.

(3) Atg5-deficient mesenchymal stem cells protect against non-alcoholic fatty liver by accelerating hepatocyte growth factor secretionCell communication and signaling : CCSDecember 3, 2024Zhang C, Ji J, Du X, Zhang L, Song Y, Wang Y, Jiang Y, Li K, Chang T.subsequent experimentation. The shRNA plasmids were purchased from Santa Cruz (sc-37111, sc-45924, sc-41445). Quantitative real-time PCR analysis The specified cells and tissues were washed, harvested, and

(4) Disruption of Autophagic Flux and Treatment with the PDPK1 Inhibitor GSK2334470 Synergistically Inhibit Renal Cell Carcinoma PathogenesisJournal of CancerJanuary 20, 2024Weimin Zhou, Ji Huang, Chuansheng Huang, Gongxian Wang, Xinhua Tutandem repeat profiling. siRNA-mediated gene silencing The siRNAs for targeted knockdown of ATG5 (Cat# sc-41445) and ATG7 (Cat# sc-41447) and the control siRNA (Cat# sc-44232) were purchased from Santa Cruz Biotechnology

(5) Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancerScience advancesApril 21, 2023Mukhopadhyay S, Encarnación-Rosado J, Lin EY, Sohn ASW, Zhang H, Mancias JD, Kimmelman AC.shGFP: 5′-TGCCCGACAACCACTACCTGA-3′-(TRCN0000072186). Small interfering RNA (siRNA) pools against ATG5 (sc-41445), LC3 (sc-43390), FTH (sc-40575), FTL (sc-40577), NCOA4 (sc-29719), SLC4A7 (sc-77885), and IL-6 (sc-39627)

(6) Conditional expression of endorepellin in the tumor vasculature attenuates breast cancer growth, angiogenesis and hyaluronan depositionMatrix biology : journal of the International Society for Matrix BiologyApril 1, 2023Chen CG, Kapoor A, Xie C, Moss A, Vadigepalli R, Ricard-Blum S, Iozzo RV.following siRNA was purchased from Santa Cruz Biotechnology and used at the designated amounts: ATG5 siRNA (sc-41445, 100 pM) and scramble control siRNA-A (sc-37007, 100 pM). Transient siRNA-mediated knockdown Transient

(7) Surfactin induces autophagy, apoptosis, and cell cycle arrest in human oral squamous cell carcinomaOral diseasesMarch 1, 2023Vo TTT, Wee Y, Cheng HC, Wu CZ, Chen YL, Tuan VP, Liu JF, Lin WN, Lee IT.

(8) TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesiclesPLoS pathogensAugust 1, 2022Sawaged S, Mota T, Piplani H, Thakur R, Lall D, McCabe E, Seo S, Sutterwala FS, Feuer R, Gottlieb RA, et al.at a concentration of 100 nM for the times indicated. ATG5 siRNA (human [Santa Cruz Biotechnology; sc-41445]), IFNAR siRNA (human [Santa Cruz Biotechnology; sc-35637]), GABARAPL1 siRNA (human [Santa Cruz Biotechnology;

(9) TGF-β1 induced autophagy in cancer associated fibroblasts during hypoxia contributes EMT and glycolysis via MCT4 upregulationExperimental cell researchAugust 1, 2022Jena BC, Das CK, Banerjee I, Bharadwaj D, Majumder R, Das S, Biswas A, Kundu M, Roy PK, Kundu CN, et al.

(10) Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growthAutophagyJune 1, 2022Chen Y, Zhang Z, Henson ES, Cuddihy A, Haigh K, Wang R, Haigh JJ, Gibson SB.

(11) MAP kinase-dependent autophagy controls phorbol myristate acetate-induced macrophage differentiation of HL-60 leukemia cellsLife sciencesMay 15, 2022Mandic M, Misirkic Marjanovic M, Vucicevic L, Jovanovic M, Bosnjak M, Perovic V, Ristic B, Ciric D, Harhaji-Trajkovic L, Trajkovic V.

(12) FGF21 promotes migration and differentiation of epidermal cells during wound healing via SIRT1-dependent autophagyBritish journal of pharmacologyMarch 1, 2022Chen X, Tong G, Fan J, Shen Y, Wang N, Gong W, Hu Z, Zhu K, Li X, Jin L, et al.

(13) Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cellsActa pharmacologica SinicaMarch 1, 2022Kim TW.

(14) Galectin-9 restricts hepatitis B virus replication via p62/SQSTM1-mediated selective autophagy of viral core proteinsNature communicationsJanuary 27, 2022Miyakawa K, Nishi M, Ogawa M, Matsunaga S, Sugiyama M, Nishitsuji H, Kimura H, Ohnishi M, Watashi K, Shimotohno K, et al.

(15) Bortezomib alleviates antibody‐mediated rejection in kidney transplantation by facilitating Atg5 expressionJournal of Cellular and Molecular MedicineDecember 1, 2021Hong Cheng, Bin Xu, Lijie Zhang, Yi Wang, Ming Chen, Shuqiu Chenpre‐experiment, and finally confirmed the best concentration. Rat Atg5 siRNA‐lentivirus (Atg5 siRNA) (sc‐41445) were acquired from Santa Cruz Biotechnology. The antibodies used for Western blot (WB) (Atg5, Atg7

(16) PABPC4 Broadly Inhibits Coronavirus Replication by Degrading Nucleocapsid Protein through Selective AutophagyMicrobiology spectrumOctober 31, 2021Jiao Y, Kong N, Wang H, Sun D, Dong S, Chen X, Zheng H, Tong W, Yu H, Yu L, et al.and purchased from GenePharma (Shanghai, China), together with the control siRNA. Human ATG5 siRNA (SC-41445), human NDP52 siRNA (SC-93738), and human MARCH8 siRNA (SC-90432) were purchased from Santa Cruz Biotechnology.

(17) Dysregulation of Caveolin-1 Phosphorylation and Nuclear Translocation Is Associated with Senescence OnsetCellsOctober 28, 2021Goutas A, Outskouni Z, Papathanasiou I, Satra M, Koliakos G, Trachana V.transfected with 50pMol siRNA against Cav-1 (Qiagen, MD, USA) or combined with 25pMol siRNA against ATG5 (#SC-41445, Santa Cruz Biotechnology Inc, Dallas, TX, USA), as well as with negative control (#SC-37007, Santa Cruz Biotechnology Inc

(18) Autophagy promotes oncolysis of an adenovirus expressing apoptin in human bladder cancer modelsInvestigational new drugsAugust 1, 2021Shang C, Zhu YL, Li YQ, Song GJ, Ge CC, Lu J, Xiu ZR, Li WJ, Li SZ, Cong JN, et al.

(19) Defining a pharmacological inhibitor fingerprint for oxytosis/ferroptosisFree Radical Biology and MedicineAugust 1, 2021David Soriano-Castell, Antonio Currais, Pamela MaherHT22 cells were plated in 60 mm dishes at 5 x 105 cells/dish and 20 pmol ATG5 siRNA (#sc-41446 mouse; #sc41445- human) or HIF1α siRNA (#sc-35562) from Santa Cruz Biotechnology or control siRNA (#1027280) from Qiagen,

(20) Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21IUBMB lifeJuly 1, 2021Santarelli R, Pompili C, Gilardini Montani MS, Romeo MA, Gonnella R, D'Orazi G, Cirone M.Lipofectamine 2000 by transfecting 30 nmol of specific or scrambled (sc) siRNAs (Santa Cruz Biotechnology, sc‐41445 and sc‐37007, respectively), according to the manufacturer's instructions. Then cells were cultured

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ATG5 siRNA (h)

ATG5 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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ATG5 siRNA (h) from Santa Cruz Biotechnology, Inc.

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