ATG5 siRNA (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemATG5 siRNA (m)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-41446
Gene Nameautophagy-related 5 (yeast)
Quantity10 µM
Speciesmouse
NCBI Full Gene Nameautophagy related 5
NCBI Gene Aliases2010107M05Rik, 3110067M24Rik, Apg5l, Atg5l, Paddy
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) SIRT5‐Mediated Desuccinylation of RAB7A Protects Against Cadmium‐Induced Alzheimer's Disease‐Like Pathology by Restoring Autophagic FluxAdvanced ScienceAugust 1, 2024Ping Deng, Tengfei Fan, Peng Gao, Yongchun Peng, Min Li, Jingdian Li, Mingke Qin, Rongrong Hao, Liting Wang, Min Li, et al.Transfection ATG5 was knocked down in Neura‐2a cells using small interfering RNAs (siRNAs) (Santa Cruz, sc‐41446, USA) transfected with Lipofectamine RNAiMAX (Thermo Fisher, 13 778 075, USA).[ 80 ] A scrambled sequence

(2) TRIM45 aggravates microglia pyroptosis via Atg5/NLRP3 axis in septic encephalopathyJournal of NeuroinflammationNovember 30, 2023Xuliang Huang, Changzhou Ye, Xinyu Zhao, Yao Tong, Wen Lin, Qingqing Huang, Yuhao Zheng, Junlu Wang, Anqi Zhang, Yunchang MoTRIM45 were purchased from Hanbio Biotechnology (Shanghai, China). Small interfering RNAs against Atg5 (sc-41446, Santa Cruz) were purchased from Santa Cruz Biotechnology. Flag-Atg5, HA-TRIM45, HA-Ub, HA-Ub-K48 and

(3) Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivoMilitary Medical ResearchFebruary 14, 2022He Y, Dong XH, Zhu Q, Xu YL, Chen ML, Liu Z.that the results from different groups were comparable, respectively. siRNA assay siRNAs for ATG5 (sc-41446) and PGRMC1 (sc-76112) were purchased from Santa Cruz Biotechnology along with control siRNA (sc-44230).

(4) A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradationiScienceNovember 19, 2021Li S, Zhang L, Zhang G, Shangguan G, Hou X, Duan W, Xi Y, Xu N, Zhang B, Dong J, et al.

(5) Dihydroartemisinin alleviates hepatic fibrosis through inducing ferroptosis in hepatic stellate cellsBioFactors (Oxford, England)September 1, 2021Zhang Z, Wang X, Wang Z, Zhang Z, Cao Y, Wei Z, Shao J, Chen A, Zhang F, Zheng S.

(6) Defining a pharmacological inhibitor fingerprint for oxytosis/ferroptosisFree Radical Biology and MedicineAugust 1, 2021David Soriano-Castell, Antonio Currais, Pamela Mahertransfection, HT22 cells were plated in 60 mm dishes at 5 x 105 cells/dish and 20 pmol ATG5 siRNA (#sc-41446 mouse; #sc41445- human) or HIF1α siRNA (#sc-35562) from Santa Cruz Biotechnology or control siRNA (#1027280)

(7) KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicityAutophagyApril 1, 2021Liu M, Pi H, Xi Y, Wang L, Tian L, Chen M, Xie J, Deng P, Zhang T, Zhou C, et al.

(8) Inositol-requiring enzyme 1α links palmitate-induced mTOR activation and lipotoxicity in hepatocytesAmerican journal of physiology. Cell physiologyDecember 1, 2020Chen Y, Griffiths A, Wang J, Zhang T, Song Q, Song Z.

(9) Heme Induces BECN1/ATG5-Mediated Autophagic Cell Death via ER Stress in NeuronsNeurotoxicity researchDecember 1, 2020Yang Z, Zhou C, Shi H, Zhang N, Tang B, Ji N.

(10) Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infectionNature communicationsJuly 15, 2020Sivangala Thandi R, Radhakrishnan RK, Tripathi D, Paidipally P, Azad AK, Schlesinger LS, Samten B, Mulik S, Vankayalapati R.

(11) Rapid and persistent loss of TXNIP in HT22 neuronal cells under carbonyl and hyperosmotic stressNeurochemistry internationalJanuary 1, 2020Dafre AL, Schmitz AE, Maher P.

(12) The Autophagy Regulator p62 Controls PTEN-Dependent CiliogenesisFrontiers in cell and developmental biologyJanuary 1, 2020Mun H, Lee EJ, Park M, Oh GT, Park JH.-UUG AGC AAU UCA CGU UCA UTT-30 , ST pharm and sc37007, Santa Cruz Biotechnology) or siRNA targeting Atg5 (sc-41446), PTEN (sc-36326), and SQSTM1 (sc-29828) using Liopfectamine RNAiMAX Reagent (Invitrogen) according

(13) Gintonin stimulates autophagic flux in primary cortical astrocytesJournal of ginseng researchJanuary 1, 2020Rahman MA, Hwang H, Nah SY, Rhim H.

(14) GRASP55 and UPR Control Interleukin-1β Aggregation and SecretionDevelopmental cellApril 8, 2019Chiritoiu M, Brouwers N, Turacchio G, Pirozzi M, Malhotra V.

(15) Autophagy Precedes Apoptosis in Angiotensin II-Induced Podocyte InjuryCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2019Seong SB, Ha DS, Min SY, Ha TS.

(16) Hyperosmotic Stress Initiates AMPK-Independent Autophagy and AMPK- and Autophagy-Independent Depletion of Thioredoxin 1 and Glyoxalase 2 in HT22 Nerve CellsOxidative medicine and cellular longevityJanuary 1, 2019Dafre AL, Schmitz AE, Maher P.HT22 cells were plated in 60 mm dishes at 5 × 105 cells/dish. For transfection, 166 pmol ATG5 siRNA (#sc-41446) or control siRNA (#sc-37007), all from Santa Cruz Biotechnology (Santa Cruz, CA) was used along with

(17) Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregatesScientific reportsJuly 3, 2018Phadwal K, Kurian D, Salamat MKF, MacRae VE, Diack AB, Manson JC.treatment. For Atg5 siRNA studies 8 μl of both the Atg5 and control SiRNA mouse (Santa Cruz biotech, sc-41446, sc-37007) were used for transfection. ‘On-bead’ tryptic digestion and LC MS identification of proteins Washed

(18) TAX1BP1 overexpression attenuates cardiac dysfunction and remodeling in STZ-induced diabetic cardiomyopathy in mice by regulating autophagyBiochimica et biophysica acta. Molecular basis of diseaseMay 1, 2018Xiao Y, Wu QQ, Duan MX, Liu C, Yuan Y, Yang Z, Liao HH, Fan D, Tang QZ.

(19) Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent AutophagyFrontiers in immunologyJanuary 1, 2018Zhou S, Gu J, Liu R, Wei S, Wang Q, Shen H, Dai Y, Zhou H, Zhang F, Lu L.

(20) Notch3/VEGF-A axis is involved in TAT-mediated proliferation of pulmonary artery smooth muscle cells: Implications for HIV-associated PAHCell death discoveryJanuary 1, 2018Guo ML, Kook YH, Shannon CE, Buch S.(University of British Columbia, Vancouver, Canada) and control Notch3 siRNA (sc-29798), RBPJ siRNA (sc-41446), and scrambled siRNA (sc-37007) were from Santa Cruz Biotechnology. Human pulmonary artery smooth muscle cell

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ATG5 siRNA (m)

ATG5 siRNA (m) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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ATG5 siRNA (m) from Santa Cruz Biotechnology, Inc.

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