BRCA2 siRNA (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemBRCA2 siRNA (h)
CompanySanta Cruz Biotechnology, Inc.
Price $293.00Supplier Page View Company Product Page
Catalog Numbersc-29825
Gene Namebreast cancer 2, early onset
Quantity10 µM
Specieshuman
NCBI Full Gene NameBRCA2 DNA repair associated
NCBI Gene AliasesBRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11
TypesiRNA/dsRNA

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The BRCA1 BRCT promotes antisense RNA production and double-stranded RNA formation to suppress ribosomal R-loopsProceedings of the National Academy of Sciences of the United States of AmericaDecember 13, 2022Chang CW, Singh AK, Li M, Guan L, Le N, Omabe K, Liang F, Liu Y.RNAPI, 1 µM CX5461 (Selectchem) was added to HEK293T cells for 4 h before harvesting. BRCA2 siRNA (sc-29825) was purchased from Santa Cruz. BRCA1 siRNA (#12519S) was purchased from Cell Signaling. siRNA was transfected

(2) Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1LNature communicationsNovember 1, 2022Zhu C, Iwase M, Li Z, Wang F, Quinet A, Vindigni A, Shao J.interfering RNAs targeting human BOD1L/FAM44A (#sc-88933), SMARCAL1 (#sc-63042), BRCA1 (#sc-29219), BRCA2 (#sc-29825), and FBH1/FBXO18 (#sc-90469) were purchased from Santa Cruz Biotechnology, Inc. Transfections and

(3) Targeting HR Repair as a Synthetic Lethal Approach to Increase DNA Damage Sensitivity by a RAD52 Inhibitor in BRCA2-Deficient Cancer CellsInternational journal of molecular sciencesApril 23, 2021Tseng WC, Chen CY, Chern CY, Wang CA, Lee WC, Chi YC, Cheng SF, Kuo YT, Chiu YC, Tseng ST, et al.BRCA2 Transfection For transient depletion of BRCA2 in MCF7 cells, we purchased siRNA against BRCA2 (sc-29825) and control (sc-37007) from Santa Cruz Biotech (CA, USA). For stable knockdown, we transfected MCF7 cells

(4) Inhibition of c-MET increases the antitumour activity of PARP inhibitors in gastric cancer modelsJournal of cellular and molecular medicineSeptember 1, 2020Koustas E, Karamouzis MV, Sarantis P, Schizas D, Papavassiliou AG.transfection experiments, we use siRNA for stable knockdown of c‐MET (sc‐35924), BRCA1 (sc‐29219) and BRCA2 (sc‐29825) and control (sc‐37007) from Santa Cruz Biotechnology and Lipofectamine 3000 (#L3000‐15 Invitrogen Corp.). 2.4

(5) FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell deathCell death & diseaseMay 22, 2018Im J, Lawrence J, Seelig D, Nho RS.fibroblasts (n = 4) were transfected with FoxM1, BRCA2, RAD51, or control siRNA (catalog No. SC-43769, SC-29825, SC-36361, SC-37007, Santa Cruz Biotechnology) using Lipofectamin RNAiMAX (Life technologies). For overexpression

(6) Preclinical rationale for combination of crizotinib with mitomycin C for the treatment of advanced colorectal cancerCancer biology & therapySeptember 2, 2017Lev A, Deihimi S, Shagisultanova E, Xiu J, Lulla AR, Dicker DT, El-Deiry WS.

(7) Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implicationsOncotargetDecember 29, 2015Park SH, Jang KY, Kim MJ, Yoon S, Jo Y, Kwon SM, Kim KM, Kwon KS, Kim CY, Woo HG.

(8) Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell deathApoptosis : an international journal on programmed cell deathSeptember 1, 2014Guaragnella N, Marra E, Galli A, Moro L, Giannattasio S.

(9) Interaction of FUS and HDAC1 regulates DNA damage response and repair in neuronsNature neuroscienceOctober 1, 2013Wang WY, Pan L, Su SC, Quinn EJ, Sasaki M, Jimenez JC, Mackenzie IR, Huang EJ, Tsai LH.and subcloning this into the Lv-CAG lentiviral vector. siRNAs siRNAs against FUS (sc-40563), BRCA2 (sc-29825) and LIG4 (sc-37394) were purchased from Santa Cruz biotech. These consisted of three to five 19–25

(10) Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignanciesHaematologicaSeptember 1, 2013Gaymes TJ, Mohamedali AM, Patterson M, Matto N, Smith A, Kulasekararaj A, Chelliah R, Curtin N, Farzaneh F, Shall S, et al.transfection (sc-35969, Santa Cruz) and ON-TARGETplus SMARTpool - Human BRCA2 (L003462-00-0005, Dharmacon) and sc-29825, Santa Cruz). Statistical analyses Two-tailed Student’s t-tests were conducted to compare viability

(11) RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1The Journal of biological chemistryNovember 23, 2012Muñoz MC, Laulier C, Gunn A, Cheng A, Robbiani DF, Nussenzweig A, Stark JM.

(12) Phytoestrogens regulate the expression of genes involved in different biological processes in BRCA2 knocked down MCF-7, MDA-MB-231 and MCF-10a cell linesOncology reportsMarch 1, 2010Bernard-Gallon DJ, Satih S, Chalabi N, Rabiau N, Bosviel R, Fontana L, Bignon YJ.and transfection and phytoestrogen treatment. BRCA2-specific siRNA were purchased from Santa Cruz Biotechnology (sc-29825). The siRNA sequences were 5'-CCA AGG AUG UUC UGU CAA Att-3', 5'-CAA GCU ACA UAU UGC AGA Att-3', and

(13) Expression analyses of nuclear receptor genes in breast cancer cell lines exposed to soy phytoestrogens after BRCA2 knockdown by TaqMan Low-Density Array (TLDA)Journal of molecular signalingMay 14, 2009Satih S, Savinel H, Rabiau N, Fontana L, Bignon YJ, Bernard-Gallon DJ.AGG AUG UUC UGU CAA Att-3', 5'-CAA GCU ACA UAU UGC AGA Att-3', and 5'-GAA ACG GAC UUG CUA UUU Att-3' (sc-29825, Santa Cruz Biotechnology). For siRNA treatments, 40–60% subconfluent proliferating cells were transfected

(14) Loss of BRCA2 promotes prostate cancer cell invasion through up-regulation of matrix metalloproteinase-9Cancer scienceMarch 1, 2008Moro L, Arbini AA, Yao JL, di Sant'Agnese PA, Marra E, Greco M.

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BRCA2 siRNA (h)

BRCA2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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BRCA2 siRNA (h) from Santa Cruz Biotechnology, Inc.

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