SignalSilence ® AMPKalpha2 siRNA I from Cell Signaling Technology

Product Specs
ItemSignalSilence ® AMPKalpha2 siRNA I
CompanyCell Signaling Technology
Price $369.00 Inquire
Catalog Number6620S
Quantity300 µl
TargetAMPK-alpha2
NCBI Gene AliasesAMPK, AMPK2, AMPKa2, PRKAA
NCBI Full Gene Nameprotein kinase AMP-activated catalytic subunit alpha 2
Research AreaMetabolism
ReactivityH
ApplicationssiRNA
TypesiRNA

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) AMPK-mediated autophagy induction by bisdemethoxycurcumin attenuates senescence and amyloid pathology in 3xTg-AD miceAutophagy RepJune 10, 2026Parul Khajuria, Dilpreet Kour, Kuhu Sharma, Lakhvinder Singh, Razia Banoo, Diksha Manhas, P Ramajayan, Utpal Nandi, Sandip B. Bharate, Zabeer Ahmed, et al.(4409S), anti-rabbit IgG Alexa flour 488 (4412S), anti-rabbit IgG Alexa flour 555 (4413S) and siRNA PRKAA2(6620S) were purchased from Cell Signalling Technology. ULK1 (SC-33182), BECN1 (SC-48341), ATG5 (SC-133158),

(2) Bisdemethoxycurcumin mitigates Alzheimer disease pathology through autophagy-mediated reduction of senescence and amyloid betabioRxivMay 28, 2025Parul Khajuria, Dilpreet Kour, Kuhu Sharma, Lakhvinder Singh, Razia Banoo, Diksha Manhas, P. Ramajayan, Utpal Nandi, Sandip Bharate, Zabeer Ahmed, et al.(4409S), anti-rabbit IgG Alexa flour 488 (4412S), anti-rabbit IgG Alexa flour 555 (4413S) and siRNA PRKAA2(6620S) were purchased from Cell Signalling Technology. ULK1 (SC-33182), BECN1 (SC-48341), ATG5 (SC-133158),

(3) Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD miceFrontiers in pharmacologyJanuary 1, 2025Kour D, Khajuria P, Sharma K, Sharma A, Sharma A, Ali SM, Wazir P, Ramajayan P, Sawant SD, Nandi U, et al.2535S, #19), NLRP3 (Cell Signaling Technology, 15101S, #3), siRNA AMPK (Cell Signaling Technology, 6620S, #3), MTOR (Cell Signaling Technology, 2972S, #9), pMTOR (Cell Signaling Technology, 5536S, #9), pCAMKK2

(4) Fluvoxamine maleate alleviates amyloid-beta load and neuroinflammation in 5XFAD mice to ameliorate Alzheimer disease pathologyFrontiers in ImmunologyJuly 29, 2024Sukhleen Kaur, Kuhu Sharma, Ankita Sharma, Kamalpreet Kaur Sandha, Syed Mudassir Ali, Riyaz Ahmed, P. Ramajayan, Parvinder Pal Singh, Zabeer Ahmed, Ajay Kumar(Santa Cruz Biotechnology-SC-20011), HRP-linked anti-goat IgG (Santa Cruz Biotechnology-SC-2354), siRNA PRKAA2 (CST-6620S), GFAP (CST-80788S), IBA1 (CST-17198S), HRP-linked anti-rabbit IgG (CST-7074S), HRP-linked anti-mouse

(5) Structure–function characterization of two enzymes from novel subfamilies of manganese peroxidases secreted by the lignocellulose-degrading Agaricales fungi Agrocybe pediades and Cyathus striatusBiotechnology for Biofuels and BioproductsJune 1, 2024María Isabel Sánchez-Ruiz, Elena Santillana, Dolores Linde, Antonio Romero, Angel T. Martínez, Francisco Javier Ruiz-Dueñas14,40 ± 7 kcat (s−1),kcat (s−1),568 ± 55,265 ± 18 kcat/KM (s−1·mM−1),kcat/KM (s−1·mM−1),5650 ± 980,6620 ± 1270 ki (µM),ki (µM),(0.34 ± 0.06)·103,(1.47 ± 0.29)·103 t1/2 (min)b,500 eq,10,40 t1/2 (min),1000

(6) Pterostilbene suppresses oxidative stress and allergic airway inflammation through AMPK/Sirt1 and Nrf2/HO‐1 pathwaysImmunity, Inflammation and DiseaseDecember 1, 2021Chang Xu, Yilan Song, Zhiguang Wang, Jingzhi Jiang, Yihua Piao, Li Li, Shan Jin, Liangchang Li, Lianhua Zhu, Guanghai Yantransfection, 16HBE cells were transfected with siControl (#6568; Cell Signaling Technology), siAMPK (#6620; Cell Signaling Technology), siSirt1 (#12241; Cell Signaling Technology) and siNrf2 (#5285; Cell Signaling Technology

(7) Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling PathwayMedical Science MonitorApril 10, 2018Jiawen You, Jun Cheng, Bing Yu, Changhua Duan, Jinghua Peng(Catalog No. 12241) (Cell Signaling Technology) and the SignalSilence AMPKa2 siRNA II kit (Catalog No. 6620) (Cell Signaling Technology) were used to knockdown the expression of the SIRT1 and the AMPK gene expression, respectively.

(8) Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling PathwayMed. Sci. MonitApril 10, 2018Jiawen You, Jun Cheng, Bing Yu, Changhua Duan, Jinghua Peng(Catalog No. 12241) (Cell Signaling Technology) and the SignalSilence AMPKa2 siRNA II kit (Catalog No. 6620) (Cell Signaling Technology) were used to knockdown the expression of the SIRT1 and the AMPK gene expression, respectively.

(9) Butein induction of HO-1 by p38 MAPK/Nrf2 pathway in adipocytes attenuates high-fat diet induced adipose hypertrophy in miceEuropean journal of pharmacologyMarch 15, 2017Wang Z, Ka SO, Lee Y, Park BH, Bae EJ.

(10) "IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis"BMC cancerJanuary 1, 0001"Perimenis P, Galaris A, Voulgari A, Prassa M, Pintzas A."

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