PXR shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) PXR activation impairs hepatic glucose metabolism partly via inhibiting the HNF4α-GLUT2 pathwayActa pharmaceutica Sinica. BMay 1, 2022Liu P, Jiang L, Kong W, Xie Q, Li P, Liu X, Zhang J, Liu M, Wang Z, Zhu L, et al.

(2) A microbial metabolite remodels the gut-liver axis following bariatric surgeryCell host & microbeMarch 10, 2021Chaudhari SN, Luo JN, Harris DA, Aliakbarian H, Yao L, Paik D, Subramaniam R, Adhikari AA, Vernon AH, Kiliç A, et al.

(3) Xiaoaiping injection enhances paclitaxel efficacy in ovarian cancer via pregnane X receptor and its downstream moleculesJournal of ethnopharmacologyOctober 28, 2020Zhang XQ, Ding YW, Chen JJ, Xiao X, Zhang W, Zhou L, Kong QW, Shi MZ, Yang J, Jiang B, et al.

(6) Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel DiseaseFrontiers in pharmacologyJanuary 1, 2020Yu Z, Yue B, Ding L, Luo X, Ren Y, Zhang J, Mani S, Wang Z, Dou W.

(8) Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by RifampicinMolecular pharmacologyAugust 1, 2017Yan L, Wang Y, Liu J, Nie Y, Zhong XB, Kan Q, Zhang L.p300 (HSH004897LVRU6P) were provided by GeneCopoeia (Rockville, MD), and shRNA plasmid targeting PXR (sc-44057-SH) was provided by Santa Cruz Biotechnology (Dallas, TX). Cell Culture and Treatment. Human colon cancer

(12) Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicityPloS oneJanuary 1, 2015Rigalli JP, Ciriaci N, Arias A, Ceballos MP, Villanueva SS, Luquita MG, Mottino AD, Ghanem CI, Catania VA, Ruiz ML.

(13) Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathwayThe Journal of nutritional biochemistrySeptember 1, 2014Dou W, Zhang J, Li H, Kortagere S, Sun K, Ding L, Ren G, Wang Z, Mani S.

(14) Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathwayThe Journal of pharmacology and experimental therapeuticsJune 1, 2013Dou W, Zhang J, Zhang E, Sun A, Ding L, Chou G, Wang Z, Mani S.

(15) Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptorPLoS neglected tropical diseasesJanuary 1, 2012Rigalli JP, Perdomo VG, Luquita MG, Villanueva SS, Arias A, Theile D, Weiss J, Mottino AD, Ruiz ML, Catania VA.

(16) Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cellsToxicologyJuly 11, 2011Rigalli JP, Ruiz ML, Perdomo VG, Villanueva SS, Mottino AD, Catania VA.

PXR shRNA Plasmid (h)