MDM2 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) Gentian violet induces apoptosis and ferroptosis via modulating p53 and MDM2 in hepatocellular carcinomaAmerican journal of cancer researchJanuary 1, 2022Chen J, Zhao F, Yang H, Wen J, Tang Y, Wan F, Zhang X, Wu J.

(2) p21(WAF1/CIP1) promotes p53 protein degradation by facilitating p53-Wip1 and p53-Mdm2 interactionBiochemical and biophysical research communicationsMarch 5, 2021Lee J, Kim J, Kim EM, Kim U, Kang AR, Park JK, Um HD.

(3) Neddylation of PTEN regulates its nuclear import and promotes tumor developmentCell researchMarch 1, 2021Xie P, Peng Z, Chen Y, Li H, Du M, Tan Y, Zhang X, Lu Z, Cui CP, Liu CH, et al.

(5) TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2American journal of respiratory and critical care medicineNovember 1, 2020Fan Y, Gu X, Zhang J, Sinn K, Klepetko W, Wu N, Foris V, Solymosi P, Kwapiszewska G, Kuebler WM.

(8) MALAT1 Activates the P53 Signaling Pathway by Regulating MDM2 to Promote Ischemic StrokeCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyJanuary 1, 2018Zhang T, Wang H, Li Q, Fu J, Huang J, Zhao Y.

(10) Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3OncotargetMay 31, 2016Yang P, Chen W, Li X, Eilers G, He Q, Liu L, Wu Y, Wu Y, Yu W, Fletcher JA, et al.

(11) Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cellsOncotargetNovember 3, 2015Slabáková E, Kharaishvili G, Smějová M, Pernicová Z, Suchánková T, Remšík J, Lerch S, Straková N, Bouchal J, Král M, et al.

(13) XI-011 enhances cisplatin-induced apoptosis by functional restoration of p53 in head and neck cancerApoptosis : an international journal on programmed cell deathNovember 1, 2014Roh JL, Park JY, Kim EH.

(14) Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in miceGastroenterologyOctober 1, 2014Wang W, Qin JJ, Voruganti S, Wang MH, Sharma H, Patil S, Zhou J, Wang H, Mukhopadhyay D, Buolamwini JK, et al.

(17) TRIAD1 is negatively regulated by the MDM2 E3 ligaseOncology reportsNovember 1, 2012Bae S, Jung JH, An IS, Kim OY, Lee MJ, Lee JH, Park IC, Lee SJ, An S.

MDM2 shRNA Plasmid (h)